1
Burk Mark, Schilling Christophe H, Burgard Anthony, Trawick John D: Methods and organisms for utilizing synthesis gas or other gaseous carbon sources and methanol. Genomatica, Burk Mark, Schilling Christophe H, Burgard Anthony, Trawick John D, GAY David, July 30, 2009: WO/2009/094485 (56 worldwide citation)

The invention provides a non-naturally occurring microbial organism having an acetyl- CoA pathway and the capability of utilizing syngas or syngas and methanol. In one embodiment, the invention provides a non-naturally occurring microorganism, comprising one or more exogenous proteins conferring to ...


2
Schilling Christophe H: Systems and methods for constructing genomic-based phenotypic models. Genomatica, Schilling Christophe H, GAY David A, December 24, 2003: WO/2003/106998 (4 worldwide citation)

The invention provides a computer implemented process for constructing a scalable output network model for a bioparticle. The process includes computer implemented steps of: (a) accessing a database of network gene components including an annotated network set of open reading frames (ORFs) of a biop ...


3
Schilling Christophe H: Compositions and methods for bioelectricity production. Genomatica, Schilling Christophe H, GAY David A, September 21, 2006: WO/2006/099220 (1 worldwide citation)

The invention provides a microbial fuel cell having a dissimilatory metal-reducing microbe expressing exogenous or native ATPase subunits, the ATPase subunits assembling into an active ATP synthase and consuming ATP in a futile cycle. The dissimilatory metal-reducing microbe can include an organism ...


4
Park Sung M, Schilling Christophe H, Palsson Bernhard O: Compositions and methods for modeling bacillus subtilis metabolism. Genomatica, Park Sung M, Schilling Christophe H, Palsson Bernhard O, GAY David A, October 2, 2003: WO/2003/081207

The invention provides an in silico model for determining a Bacillus subtilis physiological function. The model includes a data structure relating a plurality of B. subtilis reactants to a plurality of B. subtilis reactions, a constraint set for the plurality of B. subtilis reactions, and commands f ...


5
Palsson Bernhard O, Famili Imandokht, Covert Markus W, Schilling Christophe H: Human metabolic models and methods. Genomatica, Palsson Bernhard O, Famili Imandokht, Covert Markus W, Schilling Christophe H, GAY David A, October 9, 2003: WO/2003/082214

The invention provides in silico models for determining the physiological function of human cells, including human skeletal muscle cells. The models include a data structure relating a plurality of Homo sapiens reactions, a constraint set for the plurality of Homo sapiens reactions, and commands for ...


6
Palsson Bernhard O, Covert Markus W, Schilling Christophe H: Models and methods for determining systemic properties of regulated reaction networks. The Regents Of The University Of California, Genomatica, Palsson Bernhard O, Covert Markus W, Schilling Christophe H, HAILE Lisa A, September 12, 2002: WO/2002/070730

The invention provides a model of a reaction network integrated with regulatory controls related to the reactions. A method is provided for determining a systemic property of a reaction network using a model of the invention. Also provided is a method for modeling changes that occur in a reaction ne ...


7
FAMILI Imandokht, BLACK Renata Usaite, SCHILLING Christophe H: MARQUEURS DE SÉLECTION ET PROCÉDÉS ASSOCIÉS, SELECTABLE MARKERS AND RELATED METHODS. GT LIFE SCIENCES, GENOMATICA, FAMILI Imandokht, BLACK Renata Usaite, SCHILLING Christophe H, GAY David A, March 1, 2012: WO/2012/027533

The invention relates to newly identified selectable marker systems, cells for use in a selectable marker system, and methods for using the selectable marker systems.