1
Akira Terahara, Minoru Tanaka: ML-236B Derivatives and their preparation. Sankyo Company, Frishauf Holtz Goodman & Woodward, August 24, 1982: US04346227 (269 worldwide citation)

Compounds of formula (I): ##STR1## (wherein R represents a group of formula ##STR2## and the corresponding ring-closed lactones, salts (especially alkali metal salts) and esters (especially C.sub.1 -C.sub.5 alkyl esters) thereof may be prepared by subjecting ML-236B, or ML-236B carboxylic acid or a ...


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Rei Matsueda, Yuichiro Yabe, Mitsuo Yamazaki, Tatsuo Kokubu, Kunio Hiwada: Hypotensive peptides and their use. Sankyo Company, Frishauf Holtz Goodman & Woodward, October 22, 1985: US04548926 (130 worldwide citation)

Oligopeptides of formula (I) ##STR1## (wherein R.sup.1 CO-- is an acyl group. But is an isobutyl or sec-butyl group and X is a variety of organic groups) and salts and esters thereof have valuable renin inhibitory activity.


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Takao Yoshioka, Eiici Kitazawa, Tomoyuki Kurumada, Mitsuo Yamazaki, Kazou Hasegawa: Thiazolidine derivatives, their preparation and compositions containing them. Sankyo Company, Frishauf Holtz Goodman & Woodward, February 25, 1986: US04572912 (129 worldwide citation)

The compounds of formula (I): ##STR1## [in which: R.sup.1 and R.sup.2 are the same or different and each represents hydrogen or C.sub.1 -C.sub.5 alkyl;


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Atsushi Aoki, Rikiya Fukuda, Toshio Nakayabu, Keijiro Ishibashi, Chiyoko Takeichi, Mitsuo Ishida: Antibiotic substances. Sankyo Company, Flynn & Frishauf, April 13, 1976: US03950360 (118 worldwide citation)

New antibiotic substances are obtained by culturing a strain belonging to the genus Streptomyces and recovering said substances from the culture material. The new antibiotic substances possess insecticidal and acaracidal properties.


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Takashi Shiokari, Seigo Ueda, Masayuki Iwata, Yukinori Kawahara: Composition containing a penem or carbapenem antibiotic and the use of the same. Sankyo Company, Frishauf Holtz Goodman & Woodward, July 12, 1988: US04757066 (106 worldwide citation)

Administration of an N-acylated amino acid in association with a penem or carbapenem antibiotic relieves or eliminates the renal problems associated with administration of the antibiotic alone. The amino acid derivative and antibiotic may be formulated together as a composition or administered separ ...


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Masakatsu Kaneko, Koji Morita, Takeshi Imanishi: Nucleoside and oligonucleotide analogues. Daiichi Sankyo Company, Mitsubishi Kagaku Foods Corporation, Frishauf Holtz Goodman & Chick P C, January 1, 2008: US07314923 (88 worldwide citation)

A probe for a gene or a primer for starting amplification comprising an oligonucleotide analogue comprising two or more nucleoside units, wherein at least one of the nucleoside units is a structure of the formula (2): wherein A represents a C1-C4 alkylene group, and B is an unsubstituted purin-9-yl ...


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Masakatsu Kaneko, Koji Morita, Takeshi Imanishi: Nucleoside and oligonucleotide analogues. Daiichi Sankyo Company, Mitsubishi Kagaku Foods Corporation, Frishauf Holtz Goodman & Chick P C, February 26, 2008: US07335765 (77 worldwide citation)

A compound of the formula (1): wherein R1 and R2 are the same or different and represent a hydrogen atom, a hydroxyl protecting group, a phosphate group, or —P(R3)R4, wherein R3 and R4 are the same or different and represent a hydroxyl group, an amino group, an alkoxy group having from 1 to 4 carbon ...


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Matsui Katsuaki, Kurumada Tomoyuki, Ohta Noriyuki, Watanabe Ichiro, Murayama Keisuke, Morimura Syoji: Stabilization of synthetic polymers. Sankyo Company, August 15, 1972: US3684765 (73 worldwide citation)

A synthetic polymer composition is disclosed which is stabilized against photo- and thermal deterioration by incorporating in the composition an effective amount of a 4-aminopiperidine derivative.


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Kozo Kurihara, Masaru Murano: Cyclosporin formulations of mono or diglyceride fatty acid. Sankyo Company, Frishauf Holtz Goodman & Woodward, February 5, 1991: US04990337 (72 worldwide citation)

Cyclosporins are useful immunosuppressive, anti-fungal and antiphlogistic agents which are relatively insoluble in water and aqueous fluids (including body fluids). They may be rendered more soluble or dispersible in aqueous media by first dissolving them in at least one mono- or di- glyceride of a ...