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Akira Terahara, Minoru Tanaka: ML-236B Derivatives and their preparation. Sankyo Company, Frishauf Holtz Goodman & Woodward, August 24, 1982: US04346227 (268 worldwide citation)

Compounds of formula (I): ##STR1## (wherein R represents a group of formula ##STR2## and the corresponding ring-closed lactones, salts (especially alkali metal salts) and esters (especially C.sub.1 -C.sub.5 alkyl esters) thereof may be prepared by subjecting ML-236B, or ML-236B carboxylic acid or a ...


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Takahashi Masaaki, Konno Tadamori, Sunamura Katsuyuki: Reaction-current measuring method by enzyme electrode. Sankyo, July 5, 2002: JP2002-189015 (158 worldwide citation)

PROBLEM TO BE SOLVED: To provide a reaction-current measuring method with measurement accuracy and satisfactory reproducibility, in which measuring time is shortened.SOLUTION: Through the use of a three-electrode-type enzyme electrode, constituted of a working electrode, a reference electrode, and a ...


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Rei Matsueda, Yuichiro Yabe, Mitsuo Yamazaki, Tatsuo Kokubu, Kunio Hiwada: Hypotensive peptides and their use. Sankyo Company, Frishauf Holtz Goodman & Woodward, October 22, 1985: US04548926 (130 worldwide citation)

Oligopeptides of formula (I) ##STR1## (wherein R.sup.1 CO-- is an acyl group. But is an isobutyl or sec-butyl group and X is a variety of organic groups) and salts and esters thereof have valuable renin inhibitory activity.


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Takao Yoshioka, Eiici Kitazawa, Tomoyuki Kurumada, Mitsuo Yamazaki, Kazou Hasegawa: Thiazolidine derivatives, their preparation and compositions containing them. Sankyo Company, Frishauf Holtz Goodman & Woodward, February 25, 1986: US04572912 (127 worldwide citation)

The compounds of formula (I): ##STR1## [in which: R.sup.1 and R.sup.2 are the same or different and each represents hydrogen or C.sub.1 -C.sub.5 alkyl;


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Atsushi Aoki, Rikiya Fukuda, Toshio Nakayabu, Keijiro Ishibashi, Chiyoko Takeichi, Mitsuo Ishida: Antibiotic substances. Sankyo Company, Flynn & Frishauf, April 13, 1976: US03950360 (118 worldwide citation)

New antibiotic substances are obtained by culturing a strain belonging to the genus Streptomyces and recovering said substances from the culture material. The new antibiotic substances possess insecticidal and acaracidal properties.


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Shouhachi Ugawa: Image display type game apparatus. Kabushiki Kaisha Sankyo, McDermott Will & Emery, November 17, 1998: US05836819 (111 worldwide citation)

In an image display type game machine in which a play field is displayed by an image display apparatus, there are provided on the play field a left reel, a middle reel, a right reel, representing a variable display, and a plurality of pockets into which a flipped ball can enter. Upon establishment o ...


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Takashi Shiokari, Seigo Ueda, Masayuki Iwata, Yukinori Kawahara: Composition containing a penem or carbapenem antibiotic and the use of the same. Sankyo Company, Frishauf Holtz Goodman & Woodward, July 12, 1988: US04757066 (100 worldwide citation)

Administration of an N-acylated amino acid in association with a penem or carbapenem antibiotic relieves or eliminates the renal problems associated with administration of the antibiotic alone. The amino acid derivative and antibiotic may be formulated together as a composition or administered separ ...


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Masakatsu Kaneko, Koji Morita, Takeshi Imanishi: Nucleoside and oligonucleotide analogues. Daiichi Sankyo Company, Mitsubishi Kagaku Foods Corporation, Frishauf Holtz Goodman & Chick P C, January 1, 2008: US07314923 (77 worldwide citation)

A probe for a gene or a primer for starting amplification comprising an oligonucleotide analogue comprising two or more nucleoside units, wherein at least one of the nucleoside units is a structure of the formula (2): wherein A represents a C1-C4 alkylene group, and B is an unsubstituted purin-9-yl ...



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