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Davis Ward Ronda, Mook Robert Anthony Jr, Neeb Michael J, Salovich James M: Pyrimidine compounds. Smithkline Beecham Corporation, Davis Ward Ronda, Mook Robert Anthony Jr, Neeb Michael J, Salovich James M, LEVY David J, September 2, 2004: WO/2004/074244 (95 worldwide citation)

The present invention provides compounds of formula (I) : wherein all variables are as defined herein, pharmaceutical compositions containing the same, processes for preparing the same and their use as pharmaceutical agents.


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Mcelroy Andrew B, Brown Peter J, Drewry David H, Salovich James M, Schoenen Frank J: Aminobutanoic acid compounds having metalloprotease inhibiting properties. Glaxo, Mcelroy Andrew B, Brown Peter J, Drewry David H, Salovich James M, Schoenen Frank J, LEVY David J, January 6, 1994: WO/1994/000119

Aminobutanoic acids of formula (I) where R?1¿-R?5¿ are a variety of substituents, novel intermediates, a pharmaceutical composition for treating inflammatory diseases, demyelinating diseases, and tumor metastasis, methods for such treatment and processes for preparing compounds of formula (I).