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Alegria Larry Andrew, Chong Wesley Kwan Mung, Chu Shaosong, Duvadie Rohit Kumar, Li Lin, Romines William Henry Iii, Yang Yi, Bleckman Ted Michael: N-heterocyclyl-substituted amino-thiazole derivatives as protein kinase inhibitors. Pfizer, Alegria Larry Andrew, Chong Wesley Kwan Mung, Chu Shaosong, Duvadie Rohit Kumar, Li Lin, Romines William Henry Iii, Yang Yi, Bleckman Ted Michael, LUMB J Trevor, September 2, 2004: WO/2004/074283 (28 worldwide citation)

Aminothiazole compounds with N-containing cycloalkyl at the 2-amino position which are represented by the Formula (I), or a pharmaceutically acceptable prodrug of said compound, or pharmaceutically acceptable salt of said compound, modulate and/or inhibit the cell proliferation and activity of prote ...


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Kania Robert Steven, Romines William Henry Iii, Cripps Stephan James, He Mingying, Lou Jihong, Zhou Ru: Indolyl-urea derivatives of thienopyridines useful as anti-angiogenic agents. Pfizer, Kania Robert Steven, Romines William Henry Iii, Cripps Stephan James, He Mingying, Lou Jihong, Zhou Ru, LUMB J Trevor, September 12, 2003: WO/2003/074529

The invention relates to compounds represented by the formula FI and to prodrugs thereof, pharmaceutically acceptable salts or solvates of said compounds or said prodrugs, wherein X, R1 and R11 are as defined herein. The invention also relates to pharmaceutical compositions containing the compounds ...


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Romines William Henry Iii, Kania Robert Steven, Lou Jihong, Collins Michael Raymond, Cripps Stephan James, He Mingying, Zhou Ru, Palmer Cynthia Louise, Deal Judith Gail: Benzofused heteroaryl amide derivatives of thienopyridines useful as therapeutic agents, pharmaceutical compositions including the same, and methods for their use. Pfizer, Romines William Henry Iii, Kania Robert Steven, Lou Jihong, Collins Michael Raymond, Cripps Stephan James, He Mingying, Zhou Ru, Palmer Cynthia Louise, Deal Judith Gail, LUMB J Trevor, December 24, 2003: WO/2003/106462

The invention relates to compounds represented by the formula I and to prodrugs or metabolites thereof, or pharmaceutically acceptable salts or solvates of said compounds, said prodrugs, and said metabolites, wherein Z, Y, R11 and R14, R15, R16, and R17 are as defined herein. The invention also rela ...


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Bleckman Ted Michael, Palmer Cynthia Louise, Romines William Henry Iii, Varney Michael David: Compounds useful as aicarft inhibitors. Agouron Pharmaceuticals, Bleckman Ted Michael, Palmer Cynthia Louise, Romines William Henry Iii, Varney Michael David, MANDRA Raymond R, March 16, 2000: WO/2000/013688

Coumpounds of the formula (I) (where R?1¿, R?2¿, and R?3¿ are as defined in the specification) are inhibitors of AICARFT. These compounds, as well as their pharmaceutically acceptable salts, solvates, prodrugs, and pharmaceutically active metabolites, are useful in pharmaceutical compositions for tr ...