1
Paul J Galley, Ajay Thukral, Siva K Chittajallu, Stefan Weinert: Diabetes management system. Roche Diagnostics Corporation, Jill L Woodburn, April 8, 2003: US06544212 (718 worldwide citation)

A system is provided that enables glycemic control for a subject. The system includes an insulin delivery unit, a glucose sensor, and a control unit. The control unit includes a processor unit that receives glucose value readings from the glucose sensor, executes an algorithm that predicts a glucose ...


2
William F Crismore, Nigel A Surridge, Daniel R McMinn, Richard J Bodensteiner, Eric R Diebold, R Dale Delk, David W Burke, Jiaxiong Jason Ho, Robert Kitchel Earl, Brian A Heald: Electrochemical biosensor test strip. Roche Diagnostics Corporation, Richard T Roche Diagnostics Corporation Knauer, December 7, 1999: US05997817 (483 worldwide citation)

An electrochemical biosensor test strip with four new features. The test strip includes an indentation for tactile feel as to the location of the strips sample application port. The sample application port leads to a capillary test chamber, which includes a test reagent. The wet reagent includes fro ...


3
Matthias Essenpreis, Tejal A Desai, Mauro Ferrari, Derek J Hansford: Implantable analyte sensor. The Regents of the University of California, Roche Diagnostics Corporation, Brinks Hofer Gilson & Lione, June 11, 2002: US06405066 (351 worldwide citation)

An implantable analyte sensor includes a substrate, electrodes on the substrate, and a membrane on the electrodes. The membrane can comprise elemental silicon and has a glucose diffusion test result of at least 1 mg/dl in 330 min., and an albumin diffusion test result of at most 0.1 g/dl in 420 min.


4
Margret Pfeiffer, Udo Hoss: Determination of glucose concentration in tissue. Roche Diagnostics, Arent Fox Kintner & Kahn PLLC, July 18, 2000: US06091976 (324 worldwide citation)

A method for determining and monitoring tissue glucose concentration, wherein a perfusion solution is conveyed as a liquid column through a microdialysis probe implanted in the tissue and is moved to a test cell preferably arranged outside the patient's body, the volumetric flow of the perfusion sol ...


5
Hans Jurgen Kuhr, Herbert Argauer: Blood lancet system for withdrawing blood for diagnostic purposes. Roche Diagnostics, Richard T Knauer, Jill L Woodburn, June 25, 2002: US06409740 (324 worldwide citation)

Blood lancet for withdrawing blood for diagnostic purposes. It has a housing with an outlet opening for the tip of a lancet, and a lancet drive with a drive rotor driven in a sense of rotation by a drive spring. The drive rotor converts the relaxation movement of the drive spring to a pricking movem ...


6
Brit Kalatz, Udo Hoss: System for the extrapolation of glucose concentration. Roche Diagnostics, Jill L Woodburn, Richard T Knauer, Sujatha Subramaniam, August 2, 2005: US06925393 (315 worldwide citation)

A system for the extrapolation of a glucose concentration has a data input device for entering administered insulin doses and their times of administration, a data input device for entering the carbohydrates consumed or to be consumed, a unit for determining an actual glucose concentration at a poin ...


7
William F Crismore, Nigel A Surridge, Daniel R McMinn, Richard J Bodensteiner, Eric R Diebold, R Dale Delk, David W Burke, Jiaxiong Jason Ho, Robert Kitchel Earl, Brian A Heald: Electrochemical biosensor test strip. Roche Diagnostics Corporation, Brinks Hofer Gilson & Lione, August 7, 2001: US06270637 (313 worldwide citation)

An electrochemical biosensor test strip with four new features. The test strip includes an indentation for tactile feel as to the location of the strips sample application port. The sample application port leads to a capillary test chamber, which includes a test reagent. The wet reagent includes fro ...


8
Martin Gerber, Matthias Essenpreis, Wolfgang Petrich: Subcutaneous analyte sensor. Roche Diagnostics Operations, Sujatha Subramaniam, Roche Diagnostics Operations, October 4, 2005: US06952603 (307 worldwide citation)

Assembly and method for measuring the concentration of an analyte in a biological matrix. The assembly includes an implantable optical-sensing element that comprises a body, and a membrane mounted on the body in a manner such that the membrane and the body define a cavity. The membrane is permeable ...


9
Terry Allen Beaty, Lance Scott Kuhn, Vladimir Svetnik, David W Burke: Meter and method of using the meter for determining the concentration of a component of a fluid. Roche Diagnostics Corporation, Barnes & Thornburg, November 11, 2003: US06645368 (276 worldwide citation)

An apparatus and method for determining the concentration of a medically significant component of a biological fluid comprise providing a cell supporting a chemistry which reacts with the medically significant component. Placement of first and second terminals of the cell in contact with first and s ...


10
Hans Peter Haar, Gerhard Werner, Dirk Boecker, Armin Lambrecht, Joachim Kastner: Analytical device for in vivo analysis in the body of a patient. Roche Diagnostics, Jill L Woodburn, June 24, 2003: US06584335 (261 worldwide citation)

Analysis device for determining an analyte in vivo in the body of a patient, having a measuring probe with a hollow needle (