1
Rolf Moser, Lukas Birrer: Thermal cycler. Roche Diagnostic Systems, George W Johnston, William H Epstein, John P Parise, August 18, 1998: US05795547 (129 worldwide citation)

An apparatus for automatic performance of temperature cycles in a number of test tubes in which each test tube is closed by a closure and contains a predetermined volume of a liquid reaction mixture. The apparatus includes a holder, a computer-controlled automatic control system, and a device for cy ...


2
Jurg Buhler, Siegfried Muller: Vessel holder for automated analyzer. Roche Diagnostic Systems, George W Johnston, William H Epstein, John P Parise, December 23, 1997: US05700429 (80 worldwide citation)

A vessel holder for receiving a number of vessels is useful in an automated analyzer. To increase the number of vessels which can be received in the analyzer and to simplify the device for reading bar code labels, the vessel holder has an elongate body manufactured in one piece and containing a sing ...


3
R Keith Galloway, Steven S Bachand, Stephen K Schultheis: Assaying device and container for in field analysis of a specimen and later shipment of the unadulterated specimen. Roche Diagnostic Systems, Walter A Hackler, April 4, 1995: US05403551 (74 worldwide citation)

An assaying device is provided for both collecting and analyzing a sample which includes a container and an opening for collecting the sample in a chamber for storing the sample. A cap is provided for sealing the container opening and at least one assay system is attached to the container for chemic ...


4
Walter Fassbind, Emanuele Japichino: Reaction container arrangement for use in a thermal cycler. Roche Diagnostic Systems, George W Johnston, William H Epstein, John P Parise, February 24, 1998: US05720406 (36 worldwide citation)

A throwaway arrangement of reaction containers each having the same shape and dimensions for bringing about temperature cycles in a liquid mixture contained within the reaction containers. Each reaction container having a first conical wall region, and a second cylindrical wall region which at one e ...


5
Deborah A Buonagurio, Mathew Longiaru: Construction and expression of synthetic genes encoding envelope epitopes of the human T cell leukemia virus type I. Roche Diagnostic Systems, George W Johnston, Dennis P Tramaloni, November 17, 1998: US05837818 (17 worldwide citation)

A synthetic gene which codes for at least one epitope from the immunodominant conserved region of HTLV-I env. gp 21 as well as hybrid genes utilizing the synthetic gene in conjunction with other epitopes from HTLV-Ienv. gp 46 and gp 21; the corresponding gene products, recombinant vectors containing ...


6
Joseph L Di Cesare, Steven M Rosen: Method of detecting organisms in a sample. The Perkin Elmer Corporation, Roche Diagnostic Systems, George W Rauchfuss Jr, Ohlandt Greeley Ruggiero & Perle L, May 11, 1999: US05902722 (17 worldwide citation)

The presence or absence of an organism in a sample is detected by isolating the organism from the sample by a suitable affinity matrix, releasing the organism from the affinity matrix, rupturing the cells of the organism to release total nucleic acid and hydrolyzing or digesting the total nucleic ac ...


7
Mitali Ghoshal, Kathryn Sarah Schwenzer, Robert Sundoro Wu: Quinidine immunoassay and reagents. Roche Diagnostic Systems, George W Johnston, Patricia S Rocha Tramaloni, Raina Semionow, April 21, 1998: US05741715 (9 worldwide citation)

Novel quinidine derivatives are provided which can be used in an improved immunoasssay for the detection of quinidine and quinidine metabolites.


8
Raymond Albert Hui, Steven Mark Rosen, Salvatore Joseph Salmone: Reagents for a cannabinoid immunoassay. Roche Diagnostic Systems, George W Johnston, Patricia S Rocha Tramaloni, October 6, 1998: US05817766 (9 worldwide citation)

Novel benzpyran derivatives and the use of these derivatives in producing novel anti-cannabinoid antibodies are disclosed. Also disclosed is the use of these antibodies as reagents in improved immunoassays for tetrahydrocannabinol metabolites in biological fluid samples.


9
Robert Sundoro Wu: Methods of making propoxphene derivatives. Roche Diagnostic Systems, George W Johnston, Dennis P Tramaloni, October 6, 1998: US05817529 (6 worldwide citation)

The present invention provides hapten derivatives that are useful for the preparation of antigenic, antibody and label reagents having superior performance characteristics for use in immunoassays for the detection of d-propoxyphene and d-nor-propoxyphene. In the present invention the propoxyphene nu ...


10
Joseph L Di Cesare, Steven M Rosen: Detection of low level hydrophobic analytes in environmental samples using agglutination reaction capillary slide test and apparatus therefor. The Perkin Elmer Corporation, Roche Diagnostic Systems, George W Rauchfuss Jr, April 6, 1999: US05891740 (4 worldwide citation)

Apparatus and method for detection of low levels of about 1 ppb of hydrophobic analyte in environmental samples using an enclosed permeable membrane enrichment device and agglutination reaction slide test apparatus.