1
Edward L Sinofsky: Laser fusion of biological materials. Rare Earth Medical Lasers, Thomas J Engellenner, December 10, 1991: US05071417 (204 worldwide citation)

Apparatus and methods for laser fusion of biological structures are disclosed employing a laser for delivery of a beam of laser radiation to an anastomotic site, together with a reflectance sensor for measuring light reflected from the site and a controller for monitoring changes in the reflectance ...


2
Edward L Sinofsky: Endoscopic systems for photoreactive suturing of biological materials. Rare Earth Medical, Thomas J Lahive & Cockfield Engellenner, July 30, 1996: US05540677 (157 worldwide citation)

Methods and systems for endoscopic suturing of biological tissue are disclosed. Endoscopic instruments are described which serve to position a suture material at an anastomotic site and deliver laser radiation to the suture material to effect fusion. The suture material includes a structure adapted ...


3
Edward Lawrence Sinofsky: Infrared laser catheter system. Rare Earth Medical, Thomas J Lahive & Cockfield Engellenner, December 1, 1998: US05843073 (87 worldwide citation)

Laser energy produced by a laser operating in the mid-infrared region (approximately 2 micrometers) is delivered by an optical fiber in a catheter to a surgical site for biological tissue removal and repair. Disclosed laser sources which have an output wavelength in this region include: Holmium-dope ...


4
Edward L Sinofsky: Laser suturing of biological materials. Rare Earth Medical, Thomas J Lahive & Cockfield Engellenner, March 10, 1998: US05725522 (84 worldwide citation)

Methods and systems for endoscopic suturing of biological tissue are disclosed. Endoscopic instruments are described which serve to position a suture material at an anastomotic site and deliver laser radiation to the suture material to effect fusion. The suture material includes a structure adapted ...


5
Edward L Sinofsky: Photoreactive suturing of biological materials. Rare Earth Medical, Thomas J Engellenner, May 4, 1993: US05207670 (84 worldwide citation)

Materials and methods for photoreactive suturing of biological tissue are disclosed. The suture material includes a structure adapted for positioning at an anastomotic site and has at least a portion of the structure formed by a photoreactive crosslinking agent, such that upon irradiation of the str ...


6
Lincoln S Baxter, Norman Farr, Edward L Sinofsky: Phototherapy apparatus with integral stopper device. Rare Earth Medical, Thomas J Lahive & Cockfield Engellenner, July 1, 1997: US05643253 (77 worldwide citation)

Phototherapeutic instruments are disclosed having integral stopper devices which limit the penetration of an optical fiber during tissue penetrating phototherapy. In one preferred embodiment, a fluted outer sheath is disposed about an internal optical fiber. The fluted sheath is configured to expand ...


7
Edward L Sinofsky: Phototherapy methods and apparatus. Rare Earth Medical, Thomas J Lahive & Cockfield Engellenner, June 1, 1999: US05908415 (70 worldwide citation)

An optical transmissive fiber tip assembly having a radiation-scattering particles incorporated therein and a reflective end surface is disclosed for use in phototherapy. As radiation propagates through the fiber tip, a portion of the radiation is scattered in a cylindrical (or partially cylindrical ...


8
Edward L Sinofsky: Fiber optic spectroscopy. Rare Earth Medical, Thomas J Lahive & Cockfield Engellenner, June 30, 1998: US05773835 (61 worldwide citation)

Methods and devices for practicing fluorescence spectroscopy to detect abnormal or cancerous tissue employing an transparent fluoropolymer optical probe to irradiate a target region of biological material and measure the fluorescent response of the target tissue. Based on the spectral response of th ...


9
Edward L Sinofsky: Phototherapeutic apparatus with diffusive tip assembly. Rare Earth Medical, Thomas J Nutter McClennen & Fish Engellenner, September 7, 1999: US05947959 (50 worldwide citation)

Methods and devices are disclosed in which a dielectric structure is operatively coupled to phototherapeutic instrument to reflect light without substantial heating. The invention is particularly useful in light diffusive tip assemblies for phototherapy that have components which increase in tempera ...


10
Edward L Sinofsky: Loop diffusers for diffusion of optical radiation. Rare Earth Medical, Thomas J Lahive & Cockfield Engellenner, May 27, 1997: US05632767 (49 worldwide citation)

Methods and apparatus are disclosed for diffusing radiation from a optical fiber to provide a larger exposure area for phototherapy and to provide a substantially uniform energy distribution to a major portion of the exposure area. The invention is especially useful in constructing and implementing ...