1
Ramsey J Michael: Apparatus and method for performing microfluidic manipulations for chemical analysis and synthesis. Lockheed Martin Energy Systems, Ramsey J Michael, SMIRMAN Preston H, February 15, 1996: WO/1996/004547 (6 worldwide citation)

A microchip loboratory system (10) and method provide fluidic manipulations for a variety of applications, including sample injection for microchip chemical separations. The microchip is fabricated using standard photolithographic procedures and chemical wet etching, with the substrate and cover pla ...


2
Ramsey J Michael, Jacobson Stephen C: Microfluidic devices for the controlled manipulation of small volumes. Ut Battelle, Ramsey J Michael, Jacobson Stephen C, sPACE Vincent T, February 22, 2001: WO/2001/012327

A method for conducting a broad range of biochemical analyses or manipulations on a series of nano- to subnanoliter reaction volumes and an apparatus for carrying out the same are disclosed. The method and apparatus are implemented on a fluidic microchip to provide high serial throughput. The method ...


3
Jacobson Stephen C, Ramsey J Michael: Microfluidic circuit designs for performing electrokinetic manipulations that reduce the number of voltage sources and fluid reservoirs. Ut Battelle, Jacobson Stephen C, Ramsey J Michael, PACE Vincent T, June 22, 2000: WO/2000/036390

A microfabricated device and method for proportioning and mixing electokinetically manipulated biological or chemical materials is disclosed. The microfabricated device (5) mixes a plurality of materials in volumetric proportions controlled by the electrical resistances of tributary reagent channels ...


4
Jacobson Stephen C, Ramsey J Michael: A microfluidic device and method for focusing, segmenting, and dispensing of a fluid stream. Ut Battelle, Jacobson Stephen C, Ramsey J Michael, sPACE Vincent T, July 19, 2001: WO/2001/051918

A microfluidic device for forming and/or dispensing minute volume segments of a material is described. In accordance with one aspect of the present invention, a microfluidic device and method is provided for spatially confining the material in a focusing element. The device is also capable of segmen ...


5
Jacobson Stephen C, Ramsey J Michael: A microfabricated device and method for multiplexed electrokinetic focusing of fluid streams and a transport cytometry method using same. Ut Battelle, Jacobson Stephen C, Ramsey J Michael, PACE Vincent T, December 23, 1999: WO/1999/066318

One embodiment of the present invention provides a microchip (10) adapted for the simultaneous spatial confinement of electrokinetically driven fluidic material streams on the microchip. The microchip includes a focusing chamber (22) formed in the surface of the microchip and in fluid communication ...