1
Ruiyin Chu: Fusion products containing insoluble proteinaceous tag. Pierce Biotechnology, Quarles & Brady, September 2, 2003: US06613548 (11 worldwide citation)

A process is disclosed for the preparation of a recombinantly expressed fusion product comprised of a proteinaceous tag and a soluble protein of interest and the separation of the fusion product from the host cell in which it is expressed. The tag and in turn the fusion product is insoluble in the h ...


2
M Dean Savage, Laura L Sykaluk: Preparing monomeric metal ion chelator containing diacetyl glycine group linked to proteinaceous molecule. Pierce Biotechnology, December 30, 2003: US06670159 (9 worldwide citation)

A precursor for the construction of chelated metal conjugates which demonstrate improved assay performance and utility in minimizing non-specific binding while maintaining specificity for target molecules is disclosed. The precursor has tridentate functionality towards multivalent ions such as iron ...


3
Surbhi Desai, Mark Rickerd, Ineabel Horneij: Coated surfaces with high capacity for capturing target molecules. Pierce Biotechnology, October 28, 2003: US06638728 (6 worldwide citation)

New protein coated surfaces, which have a high capacity for capturing target molecules, thus yielding assays with enhanced sensitivity, are disclosed. Surfaces prepared according to the present invention contain a coating consisting essentially of streptavidin, avidin or “NeutrAvidin” in polymeric f ...


4
Paul J Haney, William Klungle: Dialysis device with air chamber. Pierce Biotechnology, Wood Herron & Evans, June 6, 2006: US07056440 (5 worldwide citation)

A device for the dialysis of a sample includes a hermetically sealed sample chamber formed by a gasket with dialysis membranes affixed to each side in facing relationship. The gasket is impermeable to the sample being dialyzed, but is penetrable and reusable such that a sample introduction mechanism ...


5
Greg Hermanson, John Charles Rogers, Joel Louette, Ryan Daniel Bomgarden, Bhavinkumar Patel: Absolute quantitation of proteins and protein modifications by mass spectrometry with multiplexed internal standards. Pierce Biotechnology, Thompson Hine, February 2, 2016: US09252003 (3 worldwide citation)

A method for absolute protein or peptide quantitation by mass spectroscopy. A sample containing a protein or peptide of interest is prepared for mass spectroscopy analysis. The sample is subjected to mass spectroscopy analysis at low resolution whereby a single additive mass spectroscopy peak is obt ...


6
Connie A Draveling: Pelletized chromatography media of agarose, dextran or acrylamide/azlactone copolymer. Pierce Biotechnology, Cahn & Samuels, March 23, 2004: US06709743 (3 worldwide citation)

A pellet composed of an aggregate of distinct beads of a chromatography media. The pellet is coherent and capable of being rapidly hydrated on addition of water to form a gel wherein said beads are swollen and substantially uniformly dispersed in the water phase.


7
HERMANSON Greg, CZERNEY Peter T, DESAI Surbhi, WENZEL Matthias S, DWORECKI Boguslawa, LEHMANN Frank G: COMPOSÉS FLUORESCENTS, FLUORESCENT COMPOUNDS. PIERCE BIOTECHNOLOGY, DYOMICS, HERMANSON Greg, CZERNEY Peter T, DESAI Surbhi, WENZEL Matthias S, DWORECKI Boguslawa, LEHMANN Frank G, LYMAN Beverly A, June 28, 2012: WO/2012/088007 (3 worldwide citation)

Compounds used as labels with properties comparable to known fluorescent compounds. The compounds can be conjugated to proteins and nucleic acids for biological imaging and analysis. Synthesis of the compounds, formation and use of the conjugated compounds, and specific non- limiting examples of eac ...


8
Kay Opperman, Barbara J Kaboord, Jean Samuel Schultz, Christopher L Etienne, Greg Hermanson: Modified nucleotides. Pierce Biotechnology, Thompson Hine, September 17, 2013: US08536323 (2 worldwide citation)

Modified nucleotides, and methods to modify nucleotides with a moiety or label, such as biotin, that permits their detection and results in a modified nucleotide, and methods of use of the modified nucleotide in quantitative and qualitative assays.


9
Caroline Clothier: Compositions and methods for utilizing mixed substrate solutions of luminols and dioxetanes. Pierce Biotechnology, February 8, 2005: US06852503 (2 worldwide citation)

A dual enzyme chemiluminescent substrate formulation useful for the independent or simultaneous analysis of the enzymes is disclosed, the formulation includes, as one substrate component, dihydrophthalazinedione, such as luminol or isoluminol, and a peroxide source and, as the other substrate compon ...


10
Babu Antharavally, Krishna Mallia: Pyrocatechol violet-metal protein assay. Pierce Biotechnology, August 12, 2009: EP2088434-A1 (2 worldwide citation)

A method for protein determination utilizing a pyrocatechol violet-metal complex, a composition used in the protein determination assay, and a kit.