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Lee Funk
Barry Craig Finzel, Lee A Funk, Robert Charles Kelly, Matthew T Reding, Nancy Anne Wicnienski: Inhibitors of HCV NS5B polymerase. Pharmacia & UpJohn Company, Jeffrey H Tidwell, Bryan C Zielinski, Peter C Richardson, August 16, 2005: US06930106 (2 worldwide citation)

The present invention provides compounds of Formula I, compositions and methods that are useful for treating viral infections and associated diseases, particularly HCV infections and associated diseases.


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Lee Funk
Fan Yang, Bo Zhang, Nancy Anne Wicnienski, Jeffrey Allen Pfefferkorn, Meredith L Greene, Ke Chen, Richard A Nugent, Matthew Todd Reding, Robert Charles Kelly, Mark A Mitchell, Lee A Funk, Richard Frederick Heier, Rebecca Merry Anderson: Inhibitors of HCV NS5B polymerase. Pharmacia & Upjohn Company, Agouron Pharmaceuticals, July 14, 2005: US20050154056-A1

The present invention relates to compounds, process for their synthesis, compositions and methods for the treatment and prevention of hepatitis C virus (HCV) infection. In particular, the present invention provides novel compounds, pharmaceutical compositions containing such compounds and methods fo ...


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George Baerveldt: Method and apparatus for inserting a glaucoma implant in an anterior and posterior segment of the eye. Pharmacia & Upjohn Company, Knobbe Martens Olson & Bear, April 18, 2000: US06050970 (214 worldwide citation)

A method of treating glaucoma in an eye utilizing an implant is disclosed. The implant comprises an elastomeric plate having first and second surfaces and an non-valved elastomeric drainage tube. The plate is positioned over a sclera of said eye beneath Tenon's capsule, such that a portion of the pl ...


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Shon R Pulley, James P Beck, Ruth E TenBrink, Jon S Jacobs: Macrocycles useful in the treatment of Alzheimers disease. Pharmacia & Upjohn Company, McDonnell Boehnen Hulbert & Berghoff, June 27, 2006: US07067507 (86 worldwide citation)

The present invention is macrocycles of the formula (X): for treating Alzheimer's disease and other similar diseases. These compounds include inhibitors of the beta-secretase enzyme for the treatment of Alzheimer's disease and other diseases characterized by deposition of A beta peptide in a mammal. ...


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Michael R Barbachyn, Steven J Brickner, Douglas K Hutchinson: Substituted oxazine and thiazine oxazolidinone antimicrobials. Pharmacia & Upjohn Company, Donald L Corneglio, Martha A Gammill, November 18, 1997: US05688792 (81 worldwide citation)

A compound of structural Formula I: ##STR1## or pharmaceutically acceptable salts thereof wherein: X is O, S, SO, SO.sub.2, SNR.sup.10 or S(O)NR.sup.10 ;


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Ake P Elhammer, Fred L Homa: Cloned DNA encoding a UDP-GalNAc: Polypeptide, N-acetylgalactosaminyltransferase. Pharmacia & Upjohn Company, Thomas A Wootton, James D Darnley Jr, August 1, 2000: US06096512 (58 worldwide citation)

The present invention relates to a method for the isolation and expression of a glycosyltransferase enzyme for use in the synthesis of oligosaccharide or polysaccharide structures on glycoproteins, glycolipids, or as free molecules. The gene coding for the enzyme N-acetylgalactosaminyltransferase an ...


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Wayne T Leblong: Convertible child-resistant blister package. Pharmacia & Upjohn Company, Flynn Thiel Boutell & Tanis P C, June 2, 1998: US05758774 (58 worldwide citation)

PIT WORLD INTELLECTUAL PROPERTY ORGANIZATION International Bureau INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY PCT) (51) International Patent Classification 6: (11) International Publication Number: WO 96/03329 B65D 75/3 Al B65D 75/34 Al (43) International Publication Date ...


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Robert C Kelly, Mark A Mitchell, Paul A Aristoff: CC-1065 analogs. Pharmacia & Upjohn Company, William G Jameson, April 14, 1998: US05739350 (44 worldwide citation)

This invention provides some new synthetically obtained compounds of formula I and II ##STR1## which are useful as chemical intermediates. Representative formula I or II compounds have also been shown to possess useful ranges of antitumor activity in standard laboratory animal tests.