1
Kath John Charles, Luzzio Michael Joseph: Pyrimidine derivates for the treatment of abnormal cell growth. Pfizer Products, Kath John Charles, Luzzio Michael Joseph, LUMB J Trevor, July 8, 2004: WO/2004/056786 (148 worldwide citation)

The invention relates to compounds of the formula (1) and to pharmaceutically acceptable salts, prodrugs and solvates thereof, wherein R1, R2, R3, R4, R5, n, A and B are as defined herein. The invention also relates to methods of treating abnormal cell growth in mammals by administering the compound ...


2
Hulin Bernard, Piotrowski David Walter: Proline derivatives and their use as dipeptidyl peptidase iv inhibitors. Pfizer Products, Hulin Bernard, Piotrowski David Walter, FULLER Grover F Jr, December 8, 2005: WO/2005/116014 (80 worldwide citation)

The invention provides compounds of formula (I), prodrugs and stereoisomers thereof, and the pharmaceutically acceptable salts of the compounds, prodrugs, and stereoisomers, wherein R1, R2, R3, HET, n, Q, X, Y, and Z are as described herein; compositions thereof; and uses thereof in treating diabeti ...


3
Changelian Paul Steven: Method of treatment of transplant rejection. Pfizer Products, Changelian Paul Steven, LUMB J Trevor, June 10, 2004: WO/2004/047843 (75 worldwide citation)

A method of treating or preventing chronic organ transplant rejection comprising administering a compound of the formula (I), wherein R?1¿, R?2¿ and R?3¿ are as defined above.


4
Douglas James Critcher, Nigel Derek Arthur Walshe, Christelle Lauret: N-(1-arylpyrazol-4L)sulfonamides and their use as parasiticides. Pfizer, Pfizer Products, Paul M Misiak, September 28, 2010: US07803832 (61 worldwide citation)

The invention relates to a sulfonamide compound of formula (I) or a pharmaceutically, veterinarily or agriculturally acceptable salt or solvate thereof, where the groups R1-R5 are described in the description, to compositions comprising such compounds, processes for their synthesis and their use as ...


5
Huang Liming, Liu Song, Lunney Elizabeth Ann, Planken Simon Paul: Substituted 2-amino-fused heterocyclic compounds. Pfizer Products, Huang Liming, Liu Song, Lunney Elizabeth Ann, Planken Simon Paul, FULLER Grover F Jr, November 8, 2007: WO/2007/125405 (59 worldwide citation)

The present invention relates to compounds of formula (I), or a pharmaceutically acceptable salt or solvate thereof, wherein: R1, R2, Z1, t, and ring A are as defined in the specification. The invention also relates to pharmaceutical compositions comprising the compounds of formula (I) and methods o ...


6
Wessel Matthew David, Chen Jinshan, Marx Matthew Arnold, Lagreca Susan Deborah: Pyrrolopyrimidine compounds useful in treatment of cancer. Pfizer Products, Wessel Matthew David, Chen Jinshan, Marx Matthew Arnold, Lagreca Susan Deborah, FULLER Grover F, May 26, 2005: WO/2005/047289 (56 worldwide citation)

The invention relates to compounds of the formula (1), or a pharmaceutically acceptable salt, prodrug or hydrates thereof, wherein X, L, R1, R2, R3 and R4 are as defined herein. The invention also relates to pharmaceutical compositions containing the compounds of formula (1) and to methods of treati ...


7
Changelian Paul Steven: Method of treatment of atherosclerosis. Pfizer Products, Changelian Paul Steven, FULLER Grover F Jr, June 9, 2005: WO/2005/051393 (47 worldwide citation)

A method of treating or preventing atherosclerosis comprising administering a compound of the formula (I) wherein R1, R2 and R3 are as defined above.


8
Reiter Lawrence Alan, Linde Ii Robert Gerald: Thrombopoietin receptor agonists. Pfizer Products, Reiter Lawrence Alan, Linde Ii Robert Gerald, FULLER Grover F Jr, March 30, 2006: WO/2006/033005 (47 worldwide citation)

A compound of the formula (I) useful as promoters of thrombopoiesis and megakaryocytopoiesis, wherein A, B, D, E, W, X, Y, Z, R1 and R2 are defined as above.


9
Changelian Paul Steven: Pyrrolo [2,3-d] pyrimidine compounds for treating transplant rejection. Pfizer Products, Changelian Paul Steven, FULLER Grover F Jr, July 7, 2005: WO/2005/060972 (46 worldwide citation)

A method of treating or preventing chronic organ transplant rejection comprising administering a compound of the formula (I) wherein R1, R2 and R3 are as defined above.


10
Chen Peng, Hong Yufeng, Humphries Paul Stuart, Johnson Jr Theodore Otto, Lafontaine Jennifer Anne, Liu Song, Lunney Elizabeht Ann: 4-pyrimidine-5-amino-pyrazole compounds. Pfizer Products, Chen Peng, Hong Yufeng, Humphries Paul Stuart, Johnson Jr Theodore Otto, Lafontaine Jennifer Anne, Liu Song, Lunney Elizabeht Ann, FULLER Grover F Jr, November 15, 2007: WO/2007/129195 (45 worldwide citation)

The present invention relates to compounds with the formula (I), or a pharmaceutically acceptable salt thereof, wherein: -Z- is -C- or -N-; and R1, R2, R3, R4 and R7 are as defined in the specification. The invention also relates to pharmaceutical compositions comprising the compounds of formula (I) ...