1
Dennis M Treu, Jeffrey H Burbank, James M Brugger: Flow-through peritoneal dialysis systems and methods with on-line dialysis solution regeneration. NxStage Medical, Ryan Kromholz & Manion S C, July 3, 2001: US06254567 (251 worldwide citation)

Peritoneal dialysis is performed by circulating peritoneal dialysis solution through a peritoneal cavity by conveying peritoneal dialysis solution through an inlet branch into the peritoneal cavity and by withdrawing peritoneal dialysis solution through an outlet branch from the peritoneal cavity. P ...


2
Jeffrey H Burbank, James M Brugger, Dennis M Treu: Fluid processing systems and methods using extracorporeal fluid flow panels oriented within a cartridge. NxStage Medical, Proskauer Rose, June 17, 2003: US06579253 (165 worldwide citation)

A first flow path is defined within a first panel that forms a part of an extracorporeal fluid circuit. A second flow path is defined within a second panel that also forms a part of the extracorporeal fluid circuit. The first and second panels are oriented in a fluid processing cartridge for mountin ...


3
Jeffrey H Burbank, James M Brugger, Dennis M Treu: Fluid processing systems and methods using extracorporeal fluid flow panels oriented within a cartridge. NxStage Medical, Proskauer Rose, February 8, 2005: US06852090 (144 worldwide citation)

A first flow path is defined within a first panel that forms a part of an extracorporeal fluid circuit. A second flow path is defined within a second panel that also forms a part of the extracorporeal fluid circuit. The first and second panels are oriented in a fluid processing cartridge for mountin ...


4
James M Brugger, Jeffrey H Burbank, Dennis M Treu: Method and apparatus for leak detection in a fluid line. NxStage Medical, Proskauer Rose, June 3, 2003: US06572576 (142 worldwide citation)

One of the most significant safety concerns in the automation of extracorporeal blood treatments such as dialysis is the risk of blood leakage. Such systems draw blood at such a high rate that a loss of integrity in the blood circuit can be catastrophic. The most reliable leak detection method known ...


5
James M Brugger, Charles David Finch, Jeffrey H Burbank: Methods, systems, and kits for the extracorporeal processing of blood. NxStage Medical, Proskauer Rose, February 28, 2006: US07004924 (130 worldwide citation)

Methods, systems, and kits for extracorporeally circulating and processing blood are described. The systems include a pump, a processing unit, and blood drawn return lines for accessing a patient's vasculature. Blood flow through the return line is measured and pump speed controlled to maintain a de ...


6
Jeffrey H Burbank, Dennis M Treu, Barry N Fulkerson, Steven A White: Interactive systems and methods for supporting hemofiltration therapies. NxStage Medical, Proskauer Rose, January 6, 2004: US06673314 (126 worldwide citation)

A hemofiltration machine at a local treatment site is linked to a remote main data base server by a local transmitting/receiving device. The machine acts as a satellite of the main data base server. The machine performs specified therapy tasks while monitoring basic safety functions and providing th ...


7
Jeffrey H Burbank, James M Brugger, Dennis M Treu: Measurement of fluid pressure in a blood treatment device. Nxstage Medical, Proskauer Rose, December 12, 2006: US07147613 (122 worldwide citation)

A first flow path is defined within a first panel that forms a part of an extracorporeal fluid circuit. A second flow path is defined within a second panel that also forms a part of the extracorporeal fluid circuit. The first and second panels are oriented in a fluid processing cartridge for mountin ...


8
Martin Stillig, Jeffrey H Burbank, James M Brugger: Devices for potting a filter for blood processing. NxStage Medical, Proskauer Rose, March 9, 2004: US06702561 (117 worldwide citation)

A device for potting a filter is described. The device comprises a housing having a first hole in the first region communicating between the surface and the lumen, and a second hole in the second region communicating between the surface and the lumen. A ridge extends around the first hole and the se ...


9
James M Brugger, Jeffrey H Burbank, Dennis M Treu: Method for performing renal replacement therapy including producing sterile replacement fluid in a renal replacement therapy unit. NxStage Medical, Proskauer Rose, November 18, 2003: US06649063 (114 worldwide citation)

A method and device for renal replacement therapy is described that sterile-filters solution that can subsequently be used as a replacement fluid in the same unit. The devices and methods include a pump that can be reversed from its normal forward-pumping direction to sterilize a container of replac ...


10
Dennis M Treu, Jeffrey H Burbank, James Brugger, Charles D Finch, Robert Thomas: Synchronized volumetric fluid balancing systems and methods. NxStage Medical, Proskauer Rose, October 28, 2003: US06638478 (110 worldwide citation)

Systems and methods balance fluid in a fluid processing procedure during which an outgoing fluid is removed from an individual and an ingoing fluid is supplied to the individual. The systems and methods supply a volume of the outgoing fluid and a volume of the ingoing fluid into a volumetric chamber ...