1
Jesus Miranda, Steven Sablotsky: Solubility parameter based drug delivery system and method for altering drug saturation concentration. Noven Pharmaceuticals, Foley & Lardner, August 12, 1997: US05656286 (286 worldwide citation)

A blend of at least two polymers, or at least one polymer and a soluble polyvinylpyrrolidone, in combination with a drug provides a pressure-sensitive adhesive composition for a transdermal drug delivery system in which the drug is delivered from the pressure-sensitive adhesive composition and throu ...


2
David P Kanios, Joseph A Gentile, Juan A Mantelle, Steven Sablotsky: Compositions and methods for topical administration of pharmaceutically active agents. Noven Pharmaceuticals, Foley & Lardner, February 17, 1998: US05719197 (219 worldwide citation)

Compositions for topical application comprising a therapeutically effective amount of a pharmaceutical agent(s), a pharmaceutically acceptable bioadhesive carrier, a solvent for the pharmaceutical agent(s) in the carrier and a clay, and methods of administering the pharmaceutical agents to a mammal ...


3
Juan Mantelle, David Houze, David Kanios: Bioadhesive compositions and methods for topical administration of active agents. Noven Pharmaceuticals, Foley & Lardner, May 13, 2003: US06562363 (181 worldwide citation)

Bioadhesive compositions in a flexible, finite form for topical application to skin or mucous membranes comprising a composition which results from an admixture of at least one PVP polymer, at least one bioadhesive, optionally a pharmaceutically acceptable solvent suitable for use with an active age ...


4
Juan A Mantelle: Compositions and methods for topical administration of pharmaceutically active agents. Noven Pharmaceuticals, Foley & Lardner, August 10, 1993: US05234957 (145 worldwide citation)

A composition for topical application comprising a therapeutically effective amount of a pharmaceutical agent(s), a flexible, finite, pharmaceutically acceptable, bioadhesive carrier, and a solvent for the pharmaceutical agent(s) in the carrier and a method of administering the pharmaceutical agent ...


5
David Kanios: Compositions and methods to effect the release profile in the transdermal administration of active agents. Noven Pharmaceuticals, Jay G Kolman Esq, October 28, 2003: US06638528 (143 worldwide citation)

Compositions and methods for the transdermal delivery of active agents up to a period of seven days or more at substantially a zero-order release rate comprising a pharmaceutically acceptable adhesive matrix and a polymeric plastic material that provides a release rate regulating effect on the activ ...


6
Jesus Miranda, Steven Sablotsky: Solubility parameter based drug delivery system and method for altering drug saturation concentration. Noven Pharmaceuticals, Foley & Lardner, February 15, 2000: US06024976 (142 worldwide citation)

A blend of at least two polymers, or at least one polymer and a soluble polyvinylpyrrolidone, in combination with a drug provides a pressure-sensitive adhesive composition for a transdermal drug delivery system in which the drug is delivered from the pressure-sensitive adhesive composition and throu ...


7
Jesus Miranda, Steven Sablotsky: Solubility parameter based drug delivery system and method for altering drug saturation concentration. Noven Pharmaceuticals, Foley & Lardner, December 12, 1995: US05474783 (142 worldwide citation)

The method of adjusting the saturation concentration of a drug in a transdermal composition for application to the dermis, which comprises mixing polymers having differing solubility parameters, so as to modulate the delivery of the drug. This results in the ability to achieve a predetermined permea ...


8
Jesus Miranda, Steven Sablotsky: Solubility parameter based drug delivery system and method for altering drug saturation concentration. Noven Pharmaceuticals, Foley & Lardner, September 28, 1999: US05958446 (124 worldwide citation)

The method of adjusting the saturation concentration of a drug in a transdermal composition for application to the dermis, which comprises mixing polymers having differing solubility parameters, so as to modulate the delivery of the drug. This results in the ability to achieve a predetermined permea ...


9
Juan A Mantelle: Compositions and methods for topical administration of pharmaceutically active agents. Noven Pharmaceuticals, Foley & Lardner, July 26, 1994: US05332576 (109 worldwide citation)

A composition for topical application comprising a therapeutically effective amount of a pharmaceutical agent(s), a flexible, finite, pharmaceutically acceptable, bioadhesive carrier, and a solvent for the pharmaceutical agent(s) in the carrier and a method of administering the pharmaceutical agent ...


10
Jesus Miranda, Steven Sablotsky: Solubility parameter based drug delivery system and method for altering drug saturation concentration. Noven Pharmaceuticals, Foley & Lardner, April 24, 2001: US06221383 (98 worldwide citation)

A blend of at least two polymers, or at least one polymer and a soluble polyvinylpyrrolidone, in combination with a drug provides a pressure-sensitive adhesive composition for a transdermal drug delivery system in which the drug is delivered from the pressure-sensitive adhesive composition and throu ...