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BUCKMAN Brad, NICHOLAS John B, SEREBRYANY Vladimir, SEIWERT Scott D: Nouveaux inhibiteurs de la réplication du virus de lhépatite c, Novel inhibitors of hepatitis c virus replication. Intermune, BUCKMAN Brad, NICHOLAS John B, SEREBRYANY Vladimir, SEIWERT Scott D, HART Daniel, November 24, 2011: WO/2011/146401 (36 worldwide citation)

The embodiments provide compounds of the general Formulae (VI), (VII), (VIII), (IX), (X), (XI), (XII), (XIII), (XIV), and (XV) as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments further provide treatment methods, including methods of treati ...


2
BUCKMAN Brad, NICHOLAS John B, SEREBRYANY Vladimir, SEIWERT Scott D: NOUVEAUX INHIBITEURS DE LA RÉPLICATION DU VIRUS DE LHÉPATITE C, NOVEL INHIBITORS OF HEPATITIS C VIRUS REPLICATION. INTERMUNE, BUCKMAN Brad, NICHOLAS John B, SEREBRYANY Vladimir, SEIWERT Scott D, MALLON Joseph J, June 28, 2012: WO/2012/087976 (16 worldwide citation)

The embodiments provide compounds of the general Formulae XV, XVI, XVII and XVIII as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments further provide treatment methods, including methods of treating a hepatitis C virus infection and methods ...


3
BUCKMAN Brad, SEREBRYANY Vladimir, NICHOLAS John B, SEIWERT Scott: PEPTIDES ANTIVIRAUX THÉRAPEUTIQUES, THERAPEUTIC ANTIVIRAL PEPTIDES. INTERMUNE, BUCKMAN Brad, SEREBRYANY Vladimir, NICHOLAS John B, SEIWERT Scott, ARNO Thomas R, April 12, 2012: WO/2012/047764 (11 worldwide citation)

The invention relates to compounds of Formula (I) (in which the variables are defined as herein) and compositions, including pharmaceutical compositions, thereof. The invention further provides treatment methods, including methods of treating a hepatitis C virus infection and methods of treating liv ...


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BUCKMAN Brad, NICHOLAS John B, SEREBRYANY Vladimir, SEIWERT Scott D: INHIBITEURS PROLINE SUBSTITUÉE DE RÉPLICATION DU VIRUS DE LHÉPATITE C, SUBSTITUTED PROLINE INHIBITORS OF HEPATITIS C VIRUS REPLICATION. INTERMUNE, BUCKMAN Brad, NICHOLAS John B, SEREBRYANY Vladimir, SEIWERT Scott D, MILLER Kimberly J, March 29, 2012: WO/2012/040242 (10 worldwide citation)

The embodiments provide compounds of the general Formulae I, la, II,IIa,III, IIIa, Illb, IV, IVa, IVb, V, Va, Vb, VI, VIa, VIb, and VIc, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments further provide treatment methods, including methods ...


5
BUCKMAN Brad, SEREBRYANY Vladimir, NICHOLAS John B, SEIWERT Scott: NOUVEAUX INHIBITEURS MACROCYCLIQUES DE LA RÉPLICATION DU VIRUS DE LHÉPATITE C, NOVEL MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS REPLICATION. INTERMUNE, BUCKMAN Brad, SEREBRYANY Vladimir, NICHOLAS John B, SEIWERT Scott, HART Daniel, April 26, 2012: WO/2012/054874 (9 worldwide citation)

The embodiments provide compounds of the general Formulae I, la, II, Ila, IIΙ, IIIa, IV, IVa, V, Va, VI and VIa, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments further provide treatment methods, including methods of treating a hepatitis ...


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BUCKMAN Brad, NICHOLAS John B, SEREBRYANY Vladimir, SEIWERT Scott D: NOUVEAUX INHIBITEURS DE LA RÉPLICATION DU VIRUS DE LHÉPATITE C, NOVEL INHIBITORS OF HEPATITIS C VIRUS REPLICATION. INTERMUNE, BUCKMAN Brad, NICHOLAS John B, SEREBRYANY Vladimir, SEIWERT Scott D, MILLER Kimberly J, March 22, 2012: WO/2012/037259 (9 worldwide citation)

The invention relates to macrocyclic compounds of Formula e I. (in which the variables are as defined herein) for use in the treatment of hepatitis C virus. Therapeutic methods, medicaments and dosage forms related thereto are also disclosed.


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BUCKMAN Brad O, NICHOLAS John B, EMAYAN Kumaraswamy, SEIWERT Scott D: [fr] ANTAGONISTES DES RÉCEPTEURS DACIDE LYSOPHOSPHATIDIQUE, [en] LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS. BUCKMAN Brad O, NICHOLAS John B, EMAYAN Kumaraswamy, SEIWERT Scott D, INTERMUNE, HART Daniel, February 21, 2013: WO/2013/025733 (1 worldwide citation)

[en] Compounds, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds to treat, prevent or diagnose diseases, disorders, or conditions associated with one or more of the lysophosphatidic acid receptors are provide ...