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Robert E Fischell, David R Fischell, Adrian R M Upton: System for treatment of neurological disorders. NeuroPace, January 18, 2000: US06016449 (574 worldwide citation)

Disclosed is a multiple electrode, closed-loop, responsive system for the treatment of certain neurological diseases such as epilepsy, migraine headaches and Parkinson's disease. Brain electrodes would be placed in close proximity to the brain or deep within brain tissue. When a neurological event s ...


2
Bruce Kirkpatrick, Benjamin D Pless: System and method for adaptive brain stimulation. NeuroPace, November 12, 2002: US06480743 (417 worldwide citation)

An implantable neurostimulator adapted to provide adaptive electrical brain stimulation includes a detection subsystem for isolating an electrographic signal characteristic and a stimulation system for applying an adaptive stimulation signal based at least in part upon the electrographic signal char ...


3
Robert E Fischell, David R Fischell, Adrian R M Upton: Responsive implantable system for the treatment of neurological disorders. NeuroPace, October 17, 2000: US06134474 (335 worldwide citation)

Disclosed is a multiple electrode, closed-loop, responsive system for the treatment of certain neurological diseases such as epilepsy, migraine headaches and Parkinson's disease. Brain electrodes would be placed in close proximity to the brain or deep within brain tissue. When a neurological event s ...


4
Benjamin D Pless, Robert E Fischell, David R Fischell: System and method for controlling epileptic seizures with spatially separated detection and stimulation electrodes. NeuroPace, July 22, 2003: US06597954 (321 worldwide citation)

A system and method for controlling epilepsy and other neurological disorders by providing electrical stimulation to a patient's brain in response to detected neurological conditions. An implantable device includes a stimulation subsystem coupled to a stimulation electrode to provide responsive ...


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Robert E Fischell, David R Fischell, Adrian R M Upton: Means and method for the treatment of neurological disorders. NeuroPace, October 3, 2000: US06128538 (292 worldwide citation)

Disclosed is a multiple electrode, closed-loop, responsive system for the treatment of certain neurological diseases such as epilepsy, migraine headaches and Parkinson's disease. Brain electrodes would be placed in close proximity to the brain or deep within brain tissue. When a neurological event s ...


7
Benjamin D Pless: Multimodal neurostimulator and process of using it. Neuropace, Morrison & Foerster, October 15, 2002: US06466822 (278 worldwide citation)

This is directed to an implantable multimodal neurostimulator having improved efficacy in treating epilepsy and other neurological disorders and to processes of using that neurostimulator. The neurostimulator itself generally has two modes of electrical stimulation: the first involves delivering a n ...


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Robert E Fischell, David R Fischell, Adrian R M Upton: Data recording methods for an implantable device. NeuroPace, March 19, 2002: US06360122 (275 worldwide citation)

Disclosed is a multiple electrode, closed-loop, responsive system for the treatment of certain neurological diseases such as epilepsy, migraine headaches and Parkinson's disease. Brain electrodes would be placed in close proximity to the brain or deep within brain tissue. When a neurological ev ...


9
Robert E Fischell, David R Fischell, Adrian R M Upton: EEG d-c voltage shift as a means for detecting the onset of a neurological event. NeuroPace, May 9, 2000: US06061593 (268 worldwide citation)

Disclosed herein is a multiple electrode, closed-loop system for the treatment of certain neurological disorders such as epilepsy, migraine headaches and Parkinson's disease. Specifically, the present invention combines a multi-electrode array with sophisticated signal processing techniques to achie ...


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Robert E Fischell, David R Fischell, Adrian R M Upton: Implantable apparatus for treating neurological disorders. NeuroPace, November 11, 2003: US06647296 (267 worldwide citation)

Disclosed is a multiple electrode, closed-loop, responsive system for the treatment of certain neurological diseases such as epilepsy, migraine headaches and Parkinson's disease. Brain electrodes would be placed in close proximity to the brain or deep within brain tissue. When a neurological ev ...



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