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TENGLER Mark, MCMAHEN Russell: FORMES POSOLOGIQUES POUR ADMINISTRATION ORALE ET MÉTHODES DE TRAITEMENT LES UTILISANT, DOSAGE FORMS FOR ORAL ADMINISTRATION AND METHODS OF TREATMENT USING THE SAME. NEOS THERAPEUTICS, TENGLER Mark, MCMAHEN Russell, TATE Rodger L, January 3, 2013: WO/2013/003622 (9 worldwide citation)

The invention relates to dosage forms that provide prolonged therapy. In particular, the invention relates to dosage forms including various pluralities of drug-containing resin particles. The invention also relates to methods of making these dosage forms and methods of treating using these dosage f ...


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Mark Tengler, Russell McMahen: Compositions and methods of making rapidly dissolving ionically masked formulations. NEOS Therapeutics, Hunton & Williams, September 23, 2014: US08840924 (8 worldwide citation)

The present invention includes compositions and methods for reduce the taste of the drug in the drug resin complex. The composition may include one or more drug-resin complexes and a highly compressible, free-flowing pharmaceutical excipient. The resin is present in an amount effective to reduce the ...


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TENGLER Mark, MCMAHEN Russell: FORMES MÉDICAMENTEUSES RÉSISTANT À LABUS, ABUSE RESISTANT DRUG FORMS. NEOS THERAPEUTICS, TENGLER Mark, MCMAHEN Russell, POSORSKE Laurence H, January 3, 2013: WO/2013/003845 (8 worldwide citation)

The invention is directed to oral drug dosage forms designed to reduce the abuse potential of an oral dosage form of an opioid analgesic. The oral drug dosage form comprises a first population of drug-resin complex particles comprising an analgesically effective amount of an opioid drug, said first ...


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Mark Tengler, Paul Taskey, Daniel Lockhart, Russ McMahen: Compositions and methods of making sustained release liquid formulations. Neos Therapeutics, Hunton & Williams, November 27, 2012: US08318210 (6 worldwide citation)

The present invention includes compositions and methods for the controlled release of active agents in a shelf-stable liquid formulation by blending one or more controlled release microbeads comprising one or more active agents, preparing a dense, thixotropic solution having a density that is at, or ...


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Tengler Mark, Taskey Paul, Lockhart Daniel, Mcmahen Russell Lee: Compositions and methods of making sustained release liquid formulations. Neos Therapeutics, Tengler Mark, Taskey Paul, Lockhart Daniel, Mcmahen Russell Lee, FLORES Edwin, September 8, 2006: WO/2006/093838 (3 worldwide citation)

The present invention includes compositions and methods for the controlled release of active agents in a shelf-stable liquid formulation by blending one or more controlled release microbeads comprising one or more active agents, preparing a dense, thixotropic solution having a density that is at, or ...


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Yashwant Vishnupant Pathak, Russell Lee McMahen, Mark Tengler: Modifying drug release in suspensions of ionic resin systems. NEOS Therapeutics, Hunton & Williams, November 20, 2012: US08313770 (2 worldwide citation)

The present invention includes compositions and methods for delivering one or more unit dosage units by modifying the release profile of an optionally coated drug-resin complex suspended in an ionic salt solution, wherein the optionally coated drug-resin complex includes one or more active agents lo ...


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Mark Tengler, Russell McMahen: Pharmaceutical composition comprising amphetamines complexed with ion-exchange resin particles. NEOS THERAPEUTICS, Hunton & Williams, February 23, 2016: US09265737 (1 worldwide citation)

The invention relates to a pharmaceutical composition comprising amphetamines complexed with ion-exchanged resin particles to form drug-resin particles. The composition provides for prolonged therapy.


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Mark Tengler, Russell McMahen: Compositions comprising methylphenidate complexed with ion-exchange resin particles. NEOS THERAPEUTICS, Hunton & Williams, July 28, 2015: US09089496 (1 worldwide citation)

Pharmaceutical compositions of methylphenidate complexed with ion-exchange resin particles to form drug-resin particles are provided. The compositions have a first plurality of drug-resin particles that are uncoated and a second plurality of drug-resin particles that are coated with a delayed releas ...


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Mark Tengler, Russell McMahen: Compositions comprising methylphenidate complexed with ion-exchange resin particles. NEOS THERAPEUTICS, Hunton & Williams, July 7, 2015: US09072680 (1 worldwide citation)

Pharmaceutical compositions of methylphenidate complexed with ion-exchange resin particles to form drug-resin particles are provided. The compositions have a first plurality of drug-resin particles that are uncoated and a second plurality of drug-resin particles that are coated with a delayed releas ...


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Mark Tengler, Russell McMahen: Composition comprising a mixture of dextro- and levo-amphetamines complexed with ion-exchange resin particles to form drug resin particles. Neos Therapeutics, Hunton & Williams, April 28, 2015: US09017731 (1 worldwide citation)

The invention relates to dosage forms that provide prolonged therapy. In particular, the invention relates to dosage forms including various pluralities of drug-containing resin particles. In a particular embodiment, the drug dosage form comprises a mixture of dextro- and levo-amphetamines complexed ...