1
Conte Immacolata, Ercolani Caterina, Narjes Frank, Pompei Marco, Rowley Michael, Stansfield Ian: Tetracyclic indole derivatives as antiviral agents. Istituto Di Ricerche Di Biologia Molecolare P Angeletti, Conte Immacolata, Ercolani Caterina, Narjes Frank, Pompei Marco, Rowley Michael, Stansfield Ian, MAN Jocelyn, May 4, 2006: WO/2006/046030 (59 worldwide citation)

The present invention relates to tetracyclic indole compounds of formula (I); wherein R1, R2, A, Ar, W, X, Y and Z are defined herein, and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising them, and their use for the treatment or prevention of infection by hepatitis C ...


2
Narjes Frank, Stansfield Ian: Tetracyclic indole derivatives as antiviral agents. Istituto Di Ricerche Di Biologia Molecolare P Angeletti, Narjes Frank, Stansfield Ian, MAN Jocelyn, March 15, 2007: WO/2007/029029 (55 worldwide citation)

The present invention relates to tetracyclic indole derivatives of formula (I): wherein Ar, A, R1, R2, L, W, X, Y and Z are defined herein, and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising them, and their use for the treatment or prevention of infection by hepati ...


3
Ercolani Caterina, Habermann Joerg, Narjes Frank, Ponzi Simona, Rowley Michael, Stansfield Ian: Tetracyclic indole derivatives as antiviral agents. Istituto Di Ricerche Di Biologia Molecolare P Angeletti, Ercolani Caterina, Habermann Joerg, Narjes Frank, Ponzi Simona, Rowley Michael, Stansfield Ian, MAN Jocelyn, May 4, 2006: WO/2006/046039 (42 worldwide citation)

The present invention relates to tetracyclic indole compounds of formula (I); wherein R1, R2, R14, R15, A, Ar, Y and Z are defined herein, and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising them, and their use for the treatment or prevention of infection by hepatit ...


4
Avolio Salvatore, Di, Filippo Marcello, Harper Steven, Narjes Frank, Pacini Barbara, Pompei Marco, Rowley Michael, Stansfield Ian: Indole acetamides as inhibitors of the hepatitis c virus ns5b polymerase. Istituto Di Ricerche Di Biologia Molecolare P Angeletti, Avolio Salvatore, Di, Filippo Marcello, Harper Steven, Narjes Frank, Pacini Barbara, Pompei Marco, Rowley Michael, Stansfield Ian, MAN Jocelyn, October 14, 2004: WO/2004/087714 (36 worldwide citation)

The present invention relates to indole and azaindole compounds of formula (I): wherein X1, X2, X3, X4, A1, Ar1, R1, R2 and n are as defined herein, and pharmaceutically acceptable salts thereof, useful in the prevention and treatment of hepatitis C infections.


5
Maccoss Malcolm, Olsen David B, Donghi Monica, Gardelli Cristina, Harper Steven, Meppen Malte, Narjes Frank, Pacini Barbara: Nucleoside aryl phosphoramidates for the treatment of rna-dependent rna viral infection. Merck & Co, Istituto Di Ricerche Di Biologia Molecolare P Angeletti, Maccoss Malcolm, Olsen David B, Donghi Monica, Gardelli Cristina, Harper Steven, Meppen Malte, Narjes Frank, Pacini Barbara, MERCK 126 East Lincoln Avenue Rahway New Jersey 07065 0907, August 23, 2007: WO/2007/095269 (35 worldwide citation)

The present invention provides nucleoside aryl phosphoramidates of structural formula (I) which are precursors to inhibitors of RNA-dependent RNA viral polymerase. These compounds are precursors to inhibitors of RNA-dependent RNA viral replication and are useful for the treatment of RNA-dependent RN ...


6
Avolio Salvatore, Harper Steven, Narjes Frank, Pacini Barbara, Rowley Michael: Indoles and azaindoles as antiviral agents. Istituto Di Ricerche Di Biologia Molecolare P Angeletti, Avolio Salvatore, Harper Steven, Narjes Frank, Pacini Barbara, Rowley Michael, MAN Jocelyn, April 21, 2005: WO/2005/034941 (32 worldwide citation)

The present invention relates to indoles and azaindoles of formula (I): wherein X1, X2, X3, X4, A1, Ar1, Ar, n, p and q are as defined herein and pharmaceutically acceptable salts thereof, useful in the prevention and treatment of hepatitis C virus infections.


7
Meppen Malte, Narjes Frank, Pacini Barbara, Gardelli Cristina, Durette Philippe L: Nucleoside cyclic phosphoramidates for the treatment of rna-dependent rna viral infection. Merck & Co, Istituto Di Ricerche Di Biologia Molecolare P Angeletti, Meppen Malte, Narjes Frank, Pacini Barbara, Gardelli Cristina, Durette Philippe L, MERCK 126 East Lincoln Avenue Rahway New Jersey 07065 0907, July 3, 2008: WO/2008/079206 (30 worldwide citation)

The present invention provides nucleoside cyclic phosphoramidates of structural formula (I) which are precursors to inhibitors of RNA-dependent RNA viral polymerase. These compounds are precursors to inhibitors of RNA-dependent RNA viral replication and are useful for the treatment of RNA-dependent ...


8
Narjes Frank, Gardelli Cristina, Donghi Monica, Attenni Barbara, Durette Philippe L: Nucleoside aryl phosphoramidates for the treatment of rna-dependent rna viral infection. Merck & Co, Istituto Di Ricerche Di Biologia Molecolare P Angeletti, Narjes Frank, Gardelli Cristina, Donghi Monica, Attenni Barbara, Durette Philippe L, MERCK 126 East Lincoln Avenue Rahway New Jersey 07065 0907, July 17, 2008: WO/2008/085508 (27 worldwide citation)

The present invention provides nucleoside aryl phosphoramidates of structural formula (I) which are precursors to inhibitors of RNA-dependent RNA viral polymerase. These compounds are precursors to inhibitors of RNA-dependent RNA viral replication and are useful for the treatment of RNA-dependent RN ...


9
Attenni Barbara, Donghi Monica, Gardelli Cristina, Meppen Malte, Narjes Frank, Pacini Barbara: Antiviral agents. Istituto Di Ricerche Di Biologia Molecolare P Angeletti, Attenni Barbara, Donghi Monica, Gardelli Cristina, Meppen Malte, Narjes Frank, Pacini Barbara, ROLLINS Anthony J, November 27, 2008: WO/2008/142055 (25 worldwide citation)

A compound of formula (I) and pharmaceutically acceptable salts thereof; compositions containing it and its use in medicine, particularly for the treatment or inhibition of HCV infections, and processes for making it are disclosed.


10
Capito Elena, Habermann Joerg, Narjes Frank, Rico, Ferreira Maria Del Rosario, Stansfield Ian: Pentacyclic indole derivatives as antiviral agents. Istituto Di Ricerche Di Biologia Molecolare P Angeletti, Capito Elena, Habermann Joerg, Narjes Frank, Rico, Ferreira Maria Del Rosario, Stansfield Ian, MAN Jocelyn, November 15, 2007: WO/2007/129119 (24 worldwide citation)

The present invention relates to pentacyclic indole derivatives of formula (I): wherein A, Ar, R1, R2, W, X, Y and Z are defined herein, and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising them, and their use for the treatment or prevention of infection by hepatitis ...