1

2
Morwick Tina Marie, Prokopowicz Anthony S, Mao Wang: Pyrazine compounds, their use and methods of preparation. Boehringer Ingelheim International, Boehringer Ingelheim Pharma & Co Kg, Morwick Tina Marie, Prokopowicz Anthony S, Mao Wang, MORRIS Michael P, February 21, 2008: WO/2008/022164 (10 worldwide citation)

The invention provides compounds according to formula (I) their use and methods for preparation wherein A, X, Y, R1, R2 and R3 are defined herein. The compounds of the invention inhibit specific serine/threonine kinases involved in inflammatory processes and aberrant cell proliferation, and are thus ...


3
Cywin Charles Lawrence, Morwick Tina Marie, Proudfoot John Robert, Thomson David: Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof. Boehringer Ingelheim Pharmaceuticals, Cywin Charles Lawrence, Morwick Tina Marie, Proudfoot John Robert, Thomson David, RAYMOND Robert P, September 10, 2004: WO/2004/075864 (7 worldwide citation)

Compounds of Formula (I) wherein R1, R2, R3, and R4 are as defined herein, or a tautomer, prodrug, solvate, or salt thereof; pharmaceutical compositions containing such compounds, and methods of modulating the glucocorticoid receptor function and methods of treating disease states or conditions medi ...


4

5
Liu Weimin, Hickey Eugene Richard, Cywin Charles Lawrence, Fleck Roman Wolfgang, Spero Denice M, Morwick Tina Marie, Proudfoot John Robert: Substituted tricyclic heterocycles and their uses. Boehringer Ingelheim Pharmaceuticals, Liu Weimin, Hickey Eugene Richard, Cywin Charles Lawrence, Fleck Roman Wolfgang, Spero Denice M, Morwick Tina Marie, Proudfoot John Robert, RAYMOND Robert P, April 21, 2005: WO/2005/035537 (5 worldwide citation)

Disclosed are substituted tricyclic heterocycle compounds of the formulas (I), (II) and (III) shown below, wherein R1, R2, R3 and R4 are described herein, which are active as anti-inflammatory agents. Also disclosed are methods of using and making such compounds.


6

7

8
Dahmann George, Hickey Eugene Richard, Li Xiang, Mao Wang, Marshall Daniel Richard, Morwick Tina Marie, Sibley Robert, Snow Roger John, Sorcek Ronald John, Wu Frank, Young Erick Richard Roush: Rho kinase inhibitors. Boehringer Ingelheim International, Boehringer Ingelheim Pharma & Co Kg, Dahmann George, Hickey Eugene Richard, Li Xiang, Mao Wang, Marshall Daniel Richard, Morwick Tina Marie, Sibley Robert, Snow Roger John, Sorcek Ronald John, Wu Frank, Young Erick Richard Roush, MORRIS Michael P, July 17, 2008: WO/2008/086047 (2 worldwide citation)

Substituted amide and urea derivatives useful as inhibitors of Rho kinase are described, which inhibitors can be useful in the treatment of various disorders such as cardiovascular diseases, cancer, neurological diseases, renal diseases, bronchial asthma, erectile dysfunction and glaucoma.


9
Abeywardane Asitha, Andersen Denise, Morwick Tina, Snow Roger, Ward Yancy: Anti-cytokine heterocyclic compounds. Boehringer Ingelheim International, Boehringer Ingelheim Pharma & Co Kg, Abeywardane Asitha, Andersen Denise, Morwick Tina, Snow Roger, Ward Yancy, MORRIS Michael P, August 14, 2008: WO/2008/098096 (1 worldwide citation)

Heterocyclic compounds which are inhibitors of Mitrogen-Activated Protein Kinase-Activated Protein Kinase-2 (MAPKAP-K2) as described, in addition to their use in the treatment of cytokine mediated diseases.


10