1
John W Parce, Robert F Zuk: Measuring with zero volume cell. Molecular Devices Corporation, Allegretti & Witcoff, March 27, 1990: US04911794 (417 worldwide citation)

Methods and apparatuses are described for determining the presence of an analyte in a sample suspected of containing the analyte. The method comprises contacting a concentrate of a determinable element capable of being detected by means of a semiconductive electrode with the electrode in the presenc ...


2
Herking Song, Dean G Hafeman: Electrochemical system for rapid detection of biochemical agents that catalyze a redox potential change. Molecular Devices Corporation, Banner & Allegretti, October 22, 1996: US05567302 (316 worldwide citation)

The present invention relates to a system for detecting, in a reliable, precise and highly sensitive manner, biochemical agents such as enzymes that catalyze a redox potential change. One electrode is used to measure redox potential changes in an aqueous electrolyte containing the biochemical agents ...


3
Dean G Hafeman, Harden M McConnell: Multiple chemically modulated capacitance determination. Molecular Devices Corporation, Allegretti & Witcoff, November 17, 1992: US05164319 (273 worldwide citation)

Apparatus and methods are provided for multiple detection of analytes employing semiconductor capacitance as the signal modulated by the analyte. A plurality of semiconductor capacitors are organized for detection (at individual sites) of changes in capacitance which are related to changes in a flui ...


4
Henry G Wada, Harden McConnell, Dean G Hafeman: Polyredox couples in analyte determinations. Molecular Devices Corporation, Allegretti & Witcoff, July 17, 1990: US04942127 (207 worldwide citation)

Enzyme or substrate determinations can be achieved by employing an organic second substrate, which produces a product which may be coupled with a metal inorganic redox couple capable of interacting with and affecting the potential of a metal electrode on a semiconductor surface. Particularly, hydrog ...


5
Henry G Wada, Harden M McConnell, Dean G Hafeman: Polyredox couples in analyte determinations. Molecular Devices Corporation, Banner & Allegretti, March 26, 1996: US05501956 (194 worldwide citation)

Enzyme or substrate determinations can be achieved by employing an organic second substrate, which produces a product which may be coupled with a metal inorganic redox couple capable of interacting with and affecting the potential of a metal electrode on a semiconductor surface. Particularly, hydrog ...


6
Douglas N Modlin, Glenn R Edwards, John C Owicki, Michael T Taylor, Samuel A Marquiss: Sample analysis systems. Molecular Devices Corporation, Kolisch Hartwell P C, January 3, 2006: US06982431 (182 worldwide citation)

Systems, and components thereof, for analyzing samples. These systems include apparatus and methods for generating, transmitting, detecting, and/or analyzing light, including without limitation high-throughput optical screening devices for analyzing samples at one or more assay sites. These systems ...


7
Dean Hafeman, John W Parce, Harden M McConnell: Device having photoresponsive electrode for determining analytes including ligands and antibodies. Molecular Devices Corporation, Bertram I Rowland, May 27, 1986: US04591550 (123 worldwide citation)

Photoresponsive devices, including a photoresponsive electrode, are provided and methods for their use to measure changes in environment at a site at or about the surface of the photoresponsive device. By employing a source of light for irradiating a site on the surface and means for biasing the pho ...


8
Douglas N Modlin, John C Owicki, Jon F Petersen, Todd E French, Carl L Wright, Jeanne A Ruiz, Lorne E Bechtel: Multi-mode light detection system. Molecular Devices Corporation, Kolisch Hartwell P C, November 30, 2004: US06825921 (108 worldwide citation)

Apparatus and methods for combining multiple modes and methods of optical detection, postprocessing, and/or feedback loops in bioanalytical measurements. The methods may include (1) positioning a composition at an examination site in a multi-mode instrument; (2) detecting light transmitted form the ...


9
Robert F Zuk, Richard D Armenta, Jonathan Briggs: Migratory detection immunoassay. Molecular Devices Corporation, Allegretti & Witcoff, September 11, 1990: US04956275 (108 worldwide citation)

Novel methods and devices are provided for detecting analytes, where the sample is placed upstream from a reagent which is a component of a signal-producing system. The detection zone is provided upstream from the sample, where the amount of reagent which becomes bound at two sites is determined and ...


10
Anne R Kopf Sill, Robert Zuk: Analyzer with improved rotor structure. Molecular Devices Corporation, Allegretti & Witcoff, November 3, 1992: US05160702 (105 worldwide citation)

An analyzer with an improved rotor structure for analyzing solid-containing and solid free liquids having an improved rotor design that utilizes chambers and channels that operate by centrifugal force and capillary action to separate and meter the liquids for testing purposes.