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Koichi Wakatake: Automatic immunity analysis apparatus with magnetic particle separation. Kabushiki Kaisha Nittec, Mitsui Pharmaceuticals, Lowe Price LeBlanc & Becker, February 2, 1993: US05183638 (125 worldwide citation)

An immunity analysis apparatus for use with magnetic particles in which a sample is transferred to a reaction vessel and the reaction vessel is conveyed past several devices for adding and agitating a magnetic particle solution, adding a stroma solution, absorbing the particles to an inner wall of t ...


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Tomino Ikuo, Takesue Mitsuyuki, Kihara Noriaki, Kitahara Takumi, Awaya Akira, Horikomi Kazutoshi, Sasaki Tadayuki, Mizuchi Akira: Pyrimidines and their pharmaceutical acceptable salts, and their use as medicines.. Mitsui Petrochemical, Mitsui Pharmaceuticals, August 1, 1990: EP0379806-A2 (72 worldwide citation)

2,6-di-, 2,4,6-, 2,5,6-tri- or 2,4,5,6-tetra-substituted pyrimidines, and 2,6-di-substituted pyridines. These compounds are useful for treatment of neurological deseases.


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Akira Awaya, Takuo Nakano, Hisashi Kobayashi, Ken E Tan, Kazutoshi Horikomi, Tadayuki Sasaki, Keiichi Yokoyama, Hiroyasu Ohno, Kozi Kato, Takumi Kitahara, Ikuo Tomino, Shigeru Isayama: Therapeutic agent for neurological diseases. Mitsui Petrochemical, Mitsui Pharmaceuticals, Sherman and Shalloway, September 25, 1990: US04959368 (35 worldwide citation)

A pharmaceutical composition comprising a pyrimidine represented by the following formula ##STR1## wherein R.sup.1 represents a hydrogen atom, an acyl group having 2 to 4 carbon atoms, an alkoxycarbonyl group having 2 to 5 carbon atoms, an alkoxycarbonylmethyl group having 3 to 5 carbon atoms, a 3,4 ...


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Yoshitaka Nagai, Hayao Abe, Masanobu Arita: Method for treating multiple sclerosis. Mitsui Pharmaceuticals, Birch Stewart Kolasch & Birch, May 12, 1992: US05112810 (24 worldwide citation)

A pharmaceutical composition containing serum thymic factor (FTS) and a method for using FTS containing compositions for treating a variety of immunodeficiencies and autoimmune diseases including multiple sclerosis, Guillain-Barre syndrome, inflammatory neuropathy, polyneuritis and other immunodemye ...


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Akira Awaya, Fumiaki Ito, Kojun Torigoe, Ikuo Tomino: Method for healing compromised tissues using pyrimidine derivatives. Mitsui Pharmaceuticals, Knobbe Martens Olson & Bear, November 2, 1999: US05976523 (20 worldwide citation)

The present invention provides a method for the screening of a wound-healing agent, which comprises determining a substance to be active as a wound-healing agent on the basis of potentiation or modification of biological activities of a growth and/or differentiation factor, a growth hormone or a cyt ...