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Dai Mingshi, Jenkins Tracy J, Guan Bing, Ghosh Shomir, Minor Charles: Ccr8 inhibitors. Millennium Pharmaceuticals, Dai Mingshi, Jenkins Tracy J, Guan Bing, Ghosh Shomir, Minor Charles, DAVIS Steven G, July 15, 2004: WO/2004/058736 (11 worldwide citation)

Disclosed is an inhibitor of CCR8 that is represented by Structural Formula (I). Also disclosed are pharmaceutical compositions comprising a pharmaceutically acceptable carrier or diluent and a CCR8 inhibitor represented by Structural Formula (I). Also disclosed is a method of treating inflammatory ...


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Guan Bing, Minor Charles, Dai Mingshi, Ghosh Shomir, Jenkins Tracy J, Li Gang, Burdi Douglas F, Bennett Robert A: Ccr8 inhibitors. Millennium Pharmaceuticals, Guan Bing, Minor Charles, Dai Mingshi, Ghosh Shomir, Jenkins Tracy J, Li Gang, Burdi Douglas F, Bennett Robert A, DAVIS Steven G HAMILTON BROOK SMITH HAMILTON BROOK SMITH & REYNOLDS PC 530 Virginia Road PO Box 9133 Concord Massachusetts 01742 9133, July 15, 2004: WO/2004/058709 (10 worldwide citation)

Disclosed are CCR8 inhibitors represented by Structural Formulas (I). The variables in Structural Formula (I) are described herein. Also disclosed are methods of treating a subject with a CCR8 mediated condition, especially asthma, by administering one of the disclosed CCR8 inhibitors to the subject ...


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