1
Dieter Banauch, Wolfgang Brummer, Wolfgang Ebeling, Roland Helger, Norbert Hennrich, Hermann Lang: Enzymatic determination of glucose. Merck Patent Gesellschaft mit beschrankter Haftung, Millen Raptes & White, June 22, 1976: US03964974 (272 worldwide citation)

Glucose is rapidly ad quantitatively determined with an analytical agent containing glucose dehydrogenase having an activity of at least 2 .mu./mg and NADH.sub.2 oxidase activity less than 0.1%, a pyridine coenzyme, a buffer and mutarotase to increase spontaneous mutarotation of alpha-glucose to bet ...


2
Helmut Wahlig, Elvira Dingeldain, Dietrich Braun: Medicinally useful, shaped mass of collagen resorbable in the body. Merck Patent Gesellschaft mit beschrankter Haftung, Millen & White, August 31, 1982: US04347234 (187 worldwide citation)

A shaped mass resorbable in the body, comprises collagen and a bioresorbable binding agent for collagen, the binding agent being selected, e.g., from polymers of C.sub.2-16 .alpha.-hydroxyalkanoic acids, polymers of natural amino acids, hydrolyzed collagen or hydrolyzed elastin.


3
Raddatz Peter Dr, Schmitges Claus J Dr, Minck Klaus Otto Dr: Amino acid derivatives.. Merck Patent, April 27, 1988: EP0264795-A2 (169 worldwide citation)

The amino acid derivatives of the formula I in which X, Z, R, R, R, E, Y and n have the meaning indicated in Claim 1, and their salts inhibit the activity of human plasma renin.


4
Mary M Bendig, Catherine A Kettleborough, Jose Saldanha: Humanized and chimeric anti-epidermal growth factor receptor monoclonal antibodies. Merck Patent Gesellschaft Mit Beschrankter Haftung, Millen White Zelano & Branigan P C, September 24, 1996: US05558864 (166 worldwide citation)

Humanized and chimeric anti-epidermal growth factor receptor (anti-EGF-R) monoclonal antibodies are disclosed, comprising an artificial modified consensus sequence for the heavy chain of the framework region of the variable region of a human immunoglobulin. Corresponding humanized and chimeric monoc ...


5
Robert Wenz, Ferdinand Driessens: Biocements having improved compressive strength. Merck Patent, Millen White Zelano & Branigan P C, December 17, 2002: US06495156 (140 worldwide citation)

The invention describes biodegradable calcium phosphate cements, in particular mixtures of calcium phosphate-containing powders of different stoichiometric composition, the precipitated hydroxylapatite present being a cation-deficient hydroxylapatite of the formula 1, with the result that the mixtur ...


6
Helmut Wahlig, Elvira Dingeldein, Dietrich Braun: Medicinally useful, shaped mass of collagen resorbable in the body. Merck Patent Gesellschaft Mit Beschrankter Haftung, Millen & White, September 22, 1981: US04291013 (126 worldwide citation)

A shaped mass resorbable in the body, comprises collagen and a bioresorbable binding agent for collagen, the binding agent being selected, e.g., from polymers of C.sub.2-16 .alpha.-hydroxyalkanoic acids, polymers of natural amino acids, hydrolyzed collagen or hydrolyzed elastin.


7
Klaus Draenert: Implantation materials and a process for the production thereof. Merck Patent Gesellschaft mit Beschrankter Haftung, Millen & White, February 15, 1983: US04373217 (122 worldwide citation)

An implantation material comprises a polymeric base of an acrylate, a polymethacrylate, a copolymer of an acrylate and a methacrylate or a mixture thereof, and 5-35% by weight of resorbable tricalcium phosphate of a particle size of 50-300 .mu.m, and an available pore volume of less than 0.1 ml/g.


8
Wenz Adolf, Stein Alfred, Schmitt Dieter: Indicator strip. Merck Patent Gesellschaft mit beschrankter Haftung, February 6, 1973: US3715192 (107 worldwide citation)

An indicator strip, useful in analytical chemical procedures, which comprises an impregnated capillary material having at least a partially transparent film on one side and on the other side, a film forming a hollow space which is in communication with said capillary material.


9
Werner Rogalski, Richard Kirchlechner, Jurgen Seubert, Rudolf Gottschlich, Rosmarie Steinigeweg, Rolf Bergmann, Helmut Wahlig, Joachim Gante: Tetracyclic compounds. Merck Patent Gesellschaft mit beschrankter Haftung, Millen & White, May 17, 1977: US04024272 (105 worldwide citation)

Tetracyclic compounds of the formula ##STR1## wherein R.sup.1, R.sup.2, R.sup.3 and R.sup.4 each are H or alkyl, R.sup.5 is H, F, Cl, Br, CF.sub.3, OH, alkyl, alkoxy, NO.sub.2, NH.sub.2, alkylamino, dialkylamino or acylamino and X is O, S, SO, SO.sub.2, NH, N-alkyl or N-acyl, alkyl and alkoxy in eac ...


10
Heinrich Planck, Christoph Elser, Albrecht Grieben, Werner Ege: Process for the preparation of bone cement. Merck Patent Gesellschaft mit beschraenkter Haftung, Millen White & Zelano, September 8, 1992: US05145250 (101 worldwide citation)

A process for the preparation of bone cement for subsequent introduction into the cavity of a bone serving to receive a prosthesis. The components serving for the production of the bone cement are introduced into a cartridge and mixed together during a mixing phase and subsequently undergo a further ...