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Bierer Donald, Mcclure Andrea, Fu Wenlang, Achebe Furahi, Ladouceur Gaetan H, Burke Michael J, Bi Cheng, Hart Barry, Dumas Jacques, Sibley Robert, Scott William J, Johnson Jeffrey, Asgari Davoud: 3-pyridyl or 4-isoquinolinyl thiazoles as c17,20 lyase inhibitors. Bayer Pharmaceuticals Corporation, Bierer Donald, Mcclure Andrea, Fu Wenlang, Achebe Furahi, Ladouceur Gaetan H, Burke Michael J, Bi Cheng, Hart Barry, Dumas Jacques, Sibley Robert, Scott William J, Johnson Jeffrey, Asgari Davoud, GREENMAN Jeffrey M, April 3, 2003: WO/2003/027085

The invention provides novel thiazoles bearing 3-pyridyl or 4-isoquinilinyl substituents, and pharmaceutical compositions thereof. The invention also provides methods of using compounds of the invention and pharmaceutical compositions thereof as inhibitors of lyases, e.g., the 17a-hydroxylase-C17,20 ...


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Scott William J, Johnson Jeffrey, Mcclure Andrea, Fu Wenlang, Zhang Chengzhi, Bierer Donald: Substituted 3-pyridyl pyrroles and 3-pyridyl pyrazoles as c17,20 lyase inhibitors. Bayer Pharmaceuticals Corporation, Scott William J, Johnson Jeffrey, Mcclure Andrea, Fu Wenlang, Zhang Chengzhi, Bierer Donald, GREENMAN Jeffrey M, April 3, 2003: WO/2003/027101

The invention provides novel substituted 3-pyridyl pyrroles and 3-pyridyl pyrazoles and pharmaceutical compositions thereof. The invention also provides methods of use of substituted 3-pyridyl pyrroles and 3-pyridyl pyrazoles and pharmaceutical compositions thereof as inhibitors of lyases, e.g., the ...


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Achebe Furahi, Mcclure Andrea C, Bierer Donald: Substituted 3-pyridyl thiophenes as c17,20 lyase inhibitors. Bayer Pharmaceuticals Corporation, Achebe Furahi, Mcclure Andrea C, Bierer Donald, GREENMAN Jeffrey M, April 3, 2003: WO/2003/027105

The invention provides novel substituted 3-pyridyl thiophenes and pharmaceutical compositions thereof. The invention also provides methods of use of substituted 3-pyridyl thiophenes, and pharmaceutical compositions thereof, as inhibitors of lyases, e.g., the 17$g(a)-hydroxylase-C17,20 enzyme. The in ...