1
Shiro Nankai, Mariko Kawaguri, Toshihiko Yoshioka, Haruhiro Tsutsumi, Kyozo Terao, Naoki Tanimoto, Masahiro Yoshioka, Hiroshi Hyodo, Takatoshi Uchigaki: Quantitative analysis method and its system using a disposable sensor. Matsushita Electric Industrial, Kyoto Daiichi Kagaku, November 30, 1993: US05266179 (738 worldwide citation)

A sensor 13 is inserted into a connector 14. A constant voltage required to obtain a response current is applied across the connector 14 by a voltage applying source 15 at timings required. A response current of the sensor 13 inserted into the connector 14 is converted into a voltage by a current-to ...


2
Shiro Nankai, Mariko Kawaguri, Mayumi Ohtani, Takashi Iijima: Biosensor and a process for preparation thereof. Matsushita Electric Industrial, Stevens Davis Miller & Mosher, June 9, 1992: US05120420 (697 worldwide citation)

A biosensor of the invention comprises an insulating base board (1) having formed thereon, in sequence, leads (2, 3, 3'), an electrode system mainly made of carbon (4, 5, 5'), an insulating layer (6) and a reaction layer (14) composed of an enzyme and an electron acceptor, and being provided thereon ...


3
Shin Ikeda, Toshihiko Yoshioka, Shiro Nankai, Haruhiro Tsutsumi, Hideyuki Baba, Yoshinobu Tokuno, Syoji Miyazaki: Biosensor, and a method and a device for quantifying a substrate in a sample liquid using the same. Matsushita Electric Industrial, Renner Otto Boisselle & Sklar, December 10, 1996: US05582697 (591 worldwide citation)

The biosensor of this invention can quantify a substrate in a sample liquid by electrochemically measuring the amount of an electron acceptor that has been reduced by electrons generated in a reaction between the substrate and an oxidoreductase. The biosensor has an electrically insulating substrate ...


4
Toshihiko Yoshioka, Shiro Nankai: Biosensor and a method for measuring a concentration of a substrate in a sample. Matsushita Electric Industrial, Renner Otto Boisselle & Sklar, November 23, 1993: US05264103 (589 worldwide citation)

The present invention provides a biosensor comprising an electrical insulating substrate, a main electrode system formed on the substrate and having a working electrode and a counter electrode, a reaction layer provided in contact with or in the vicinity of the main electrode system and containing a ...


5
Kenichi Nakamura, Shiro Nankai, Takashi Iijima, Masataro Fukuda: Enzyme electrode. Matsushita Electric Industrial, Wenderoth Lind & Ponack, September 23, 1980: US04224125 (545 worldwide citation)

An enzyme electrode, which comprises an oxidoreductase including, where necessary, a coenzyme; a redox polymer acting as an electron mediator in an enzymatic reaction; and an electron collector, wherein the oxidoreductase and the redox polymer are both maintained in the immobilized state on or in th ...


6
Shiro Nankai, Mariko Kawaguri, Tashi Iijima: Biosensor and method for making the same. Matsushita Electric Industrial, Lowe Price LeBlanc Becker & Shur, January 30, 1990: US04897173 (473 worldwide citation)

This invention relates to a biosensor which comprises an insulative base, an electrode system formed on the substrate and primarily made of carbon, and a perforated body having an enzyme and an electron acceptor and integrally combined with the electrode system whereby a concentration of a specific ...


7
Toshihiko Yoshioka, Shiro Nankai: Biosensor utilizing enzyme and a method for producing the same. Matsushita Electric Industrial, Panitch Schwarze Jacobs & Nadel, March 9, 1993: US05192415 (429 worldwide citation)

The biosensor of the present invention quantifies a substrate contained in a sample liquid by reducing electron acceptors using electron generated in a reaction of the substrate to enzyme and then by measuring the reduced amount of the electron acceptors electrochemically. The biosensor has an elect ...


8
Shin Ikeda, Toshihiko Yoshioka, Shiro Nankai, Haruhiro Tsutsumi, Hideyuki Baba, Yoshinobu Tokuno, Syoji Miyazaki: Biosensor, and a method and a device for quantifying a substrate in a sample liquid using the same. Matsushita Electric Industrial, Renner Otto Boisselle & Sklar, July 22, 1997: US05650062 (416 worldwide citation)

The biosensor of this invention can quantify a substrate in a sample liquid by electrochemically measuring the amount of an electron acceptor that has been reduced by electrons generated in a reaction between the substrate and an oxidoreductase. The biosensor has an electrically insulating substrate ...


9
Shin Ikeda, Mariko Miyahara, Toshihiko Yoshioka, Shiro Nankai: Biosensor and method for producing the same. Matsushita Electric Industrial, Panitch Schwarze Jacobs & Nadel P C, November 19, 1996: US05575895 (415 worldwide citation)

A biosensor for quantification of a specific component contained in various biological samples comprises an electrically insulating base plate, an electrode system including a working electrode and a counter electrode which are provided on the electrically insulating base plate, a reaction layer for ...


10
Toshihiko Yoshioka, Mariko Kawaguri, Shiro Nankai: Preparation of biosensor having a layer containing an enzyme, electron acceptor and hydrophilic polymer on an electrode system. Matsushita Electric Industrial, Wenderoth Lind & Ponack, July 20, 1993: US05229282 (402 worldwide citation)

The present invention relates to a process of preparation of a biosensor comprising forming an electrode system mainly containing carbon on an insulating base plate, treating the surface of electrode system with an organic solvent, and then arranging a reaction layer on the electrode system to give ...



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