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Disalvo Darren, Kuzmich Daniel, Mao Can, Razavi Hossein, Sarko Christopher, Swinamer Alan David, Thomson David, Zhang Qiang: Indazole compounds as ccr1 receptor antagonists. Boehringer Ingelheim International, Boehringer Ingelheim Pharma & Co Kg, Disalvo Darren, Kuzmich Daniel, Mao Can, Razavi Hossein, Sarko Christopher, Swinamer Alan David, Thomson David, Zhang Qiang, MORRIS Michael P, November 5, 2009: WO/2009/134666 (13 worldwide citation)

Disclosed indazoles compounds that are useful as antagonists of CCR1 activity and are thus useful for treating a variety of diseases and disorders that are mediated or sustained through the activity of CCR1 including autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. Also disc ...


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Cook Brian Nicholas, Harcken Christian, Lee Thomas Wai Ho, Liu Pingrong, Mao Can, Lord John, Mao Wang, Raudenbush Brian Christopher, Razavi Hossein, Sarko Christopher Ronald, Swinamer Alan David: Pyrazole compounds as ccr1 antagonists. Boehringer Ingelheim International, Boehringer Ingelheim Pharma & Co Kg, Cook Brian Nicholas, Harcken Christian, Lee Thomas Wai Ho, Liu Pingrong, Mao Can, Lord John, Mao Wang, Raudenbush Brian Christopher, Razavi Hossein, Sarko Christopher Ronald, Swinamer Alan David, MORRIS Michael P, November 12, 2009: WO/2009/137338 (13 worldwide citation)

Disclosed are compounds of the formula I which block the interaction of CCR1 and its ligands and are thus useful for treating a variety of diseases and disorders that are mediated or sustained through the activity of CCR1 including autoimmune diseases, such as rheumatoid arthritis and multiple scler ...


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BETAGERI Rajashekhar, COOK Brian Nicholas, DISALVO Darren, HARCKEN Christian, KUZMICH Daniel, LIU Pingrong, LORD John, MAO Can, RAZAVI Hossein: COMPOSÉS DE PYRAZOLOPIPÉRIDINE EN TANT QUANTAGONISTES DE RÉCEPTEUR CCR1, PYRAZOLOPIPERIDINE COMPOUNDS AS CCR1 RECEPTOR ANTAGONISTS. BOEHRINGER INGELHEIM INTERNATIONAL, BETAGERI Rajashekhar, COOK Brian Nicholas, DISALVO Darren, HARCKEN Christian, KUZMICH Daniel, LIU Pingrong, LORD John, MAO Can, RAZAVI Hossein, MORRIS Michael P, June 28, 2012: WO/2012/087782 (1 worldwide citation)

Disclosed are compounds of the formula (I), useful for treating a variety of diseases and disorders that are mediated or sustained through the activity of CCR1 including autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. Also disclosed are methods of making and methods of usin ...