1
Douglas N Modlin, Glenn R Edwards, Michael T Taylor, Samuel A Marquiss: Light detection device. LJL BioSystems, Kolisch Hartwell Dickinson McCormack & Heuser, June 6, 2000: US06071748 (187 worldwide citation)

A high-throughput light detection instrument and method are described. Confocal optics structure enables exclusive light detection from a sensed volume in a composition.


2
Todd E French, Douglas N Modlin, John C Owicki, James S Richey, Lev J Leytes, Enal S Razvi: Methods and apparatus for detecting nucleic acid polymorphisms. LJL BioSystems, Kolisch Hartwell Dickinson McCormack & Heuser, October 2, 2001: US06297018 (150 worldwide citation)

Methods and apparatus for detecting polynucleotide hybridization in luminescence-based assays. The methods may include (1) allele-specific hybridization, using luminescence detection, (2) allele-specific oligonucleotide ligation, using dye-labeled oligonucleotide ligation with luminescence resonance ...


3
Brian D Warner, Benjamin T Nordell, Bruce J Richardson, Amer El Hage: Releasable multiwell plate cover. Chiron Corporation, LJL Biosystems, Robert P Blackburn, Kenneth M Goldman, Peter J Dehlinger, February 18, 1997: US05604130 (118 worldwide citation)

A cover effective to releasably seal a multiwell container, such as a microtitration plate, is disclosed. The cover contains a pad, fashioned from a flexible polymer sheet, and a plurality of resiliently compressible ridges formed on the sheet. The ridges are deformable, such that application of pre ...


4
Douglas N Modlin, Glenn R Edwards, Michael T Taylor, Samuel A Marquiss, Amer El Hage, Craig S Barker, Lorne B Bechtel, Rick V Stellmacher, Philip A Granieri Jr, Robert M Lembi Sr: Light detection device having an optical-path switching mechanism. LJL BioSystems, Kolisch Hartwell Dickinson McCormack & Heuser, August 1, 2000: US06097025 (90 worldwide citation)

A high-throughput light detection instrument and method are described. In some embodiments, switch mechanisms and optical relay structures permit different light sources and/or detectors to be selected for different applications. In other embodiments, switch mechanisms and optical paths permit top/b ...


5
Samuel A Marquiss, Christopher G Cesar, Jon F Petersen, David P Stumbo, Amer El Hage, Glenn R Edwards, Douglas N Modlin, Lev J Leytes, Samuel Burd: Integrated sample-processing system. LJL Biosystems, Kolisch Hartwell P C, June 7, 2005: US06902703 (69 worldwide citation)

The invention provides an integrated sample-processing system and components thereof for preparing and/or analyzing samples. The components may include a transport module, a fluidics module, and an analysis module, among others.


6
Samuel A Marquiss: Apparatus for holding reagent and sample vessels. LJL Biosystems, Lumen Intellectual Property Services, April 14, 1998: US05738827 (54 worldwide citation)

An apparatus for holding reagent and sample vessels. The apparatus has reagent and sample vessel racks, a carousel supporting the racks, guiding pins that serve to guide the racks as they are mounted on the carousel and also serve to attach the racks to the carousel. Each of the racks has a handle t ...


7
Douglas N Modlin: Sample holders with reference fiducials. LJL BioSystems, Kolisch Hartwell Dickinson McCormack & Heuser, July 10, 2001: US06258326 (47 worldwide citation)

Reference fiducials for sample holders. The reference fiducials may be configured to provide information that facilitates sample handling and/or analysis. The sample holders may include microplates and biochips.


8
Samuel A Marquiss: Labware identification system. LJL Biosystems, Lumen Intellectual Property Services, September 2, 1997: US05663545 (39 worldwide citation)

The invention presents a system for automatically identifying labware and sample containers. Labeled sample containers are inserted into the reception slots of a labeled labware. A sample condition label is affixed below each reception slot. The sample condition label is covered by the sample contai ...


9
Michael T Taylor, Amer El Hage, Glenn R Edwards, Douglas N Modlin: Chemiluminescence detection device. LJL BioSystems, Kolisch Hartwell Dickinson McCormack & Heuser, February 13, 2001: US06187267 (35 worldwide citation)

A device for detecting chemiluminescence from a sample. The device may include a stage for supporting a sample and one or more of the following elements: (1) an optics head, (2) an optical relay structure for transmitting chemiluminescence from the sample to a detector, (3) a drive mechanism, (4) a ...


10
Samuel A Marquiss, Christopher G Cesar, Jon F Petersen, David P Stumbo, Amer El Hage, Glenn R Edwards, Douglas N Modlin, Ley J Leytes, Samuel Burd: Integrated sample-processing system. LJL BioSystems, Kolisch Hartwell P C, January 4, 2005: US06838051 (34 worldwide citation)

The invention provides an integrated sample-processing system and components thereof for preparing and/or analyzing samples. The components may include a transport module, a fluidics module, and an analysis module, among others.