1
Halland Nis, Nazare M, Lindenschmidt Andreas, Rkyek Omar, Urmann Matthias, Alonso Jorge: A transition metal catalyzed synthesis of n-aminoindoles. Sanofi Aventis, Halland Nis, Nazare M, Lindenschmidt Andreas, Rkyek Omar, Urmann Matthias, Alonso Jorge, THEN Johann, October 23, 2008: WO/2008/125207 (46 worldwide citation)

The present invention relates to a process for the regioselective synthesis of compounds of the formula (I), wherein R0; R1; R2; R3; R4; R5; R6; A1; A2; A3; A4, Q, T and J have the meanings indicated in the claims. The present invention provides a direct transition metal catalyzed process to a wide ...


2
Alonso Jorge, Lindenschmidt Andreas, Nazare Marc, R Kyen Omar, Urmann Mathias, Halland Nis: A regioselective metal catalyzed synthesis of annelated benzimidazoles and azabenzimidazoles. Sanofi Aventis, Alonso Jorge, Lindenschmidt Andreas, Nazare Marc, R Kyen Omar, Urmann Mathias, Halland Nis, THEN Johann, December 31, 2008: WO/2009/000412 (38 worldwide citation)

A regioselective metal catalyzed synthesis of benzimidazoles and azabenzimidazoles The present invention relates to a process for the regioselective synthesis of compounds of the formula (I), wherein R1; R2; R3; R4; J1; J2; J3; J4 and G have the meanings indicated in the claims. The present inventio ...


3
Kallus Christopher, Heitsch Holger, Lindenschmidt Andreas, Grueneberg Sven, Szillat Hauke: (De) Imidazol-derivate als tafia-inhibitoren, (En) Imidazole derivatives used as tafia inhibitors. Sanofi Aventis Deutschland, Kallus Christopher, Heitsch Holger, Lindenschmidt Andreas, Grueneberg Sven, Szillat Hauke, November 10, 2005: WO/2005/105781 (13 worldwide citation)

(EN) The invention relates to compounds of formula (I), which are inhibitors of the activated thrombin-activatable fibrinolysis inhibitor. The compounds of formula (I) are suited for producing medicaments for the prevention and treatment of diseases accompanied by thromboses, embolisms, hypercoagula ...


4
Alonso Jorge, Lindenschmidt Andreas, Nazaré Marc, Halland Nis, Rkyek Omar, Urmann Matthias: A regioselective palladium catalyzed synthesis of benzimidazoles and azabenzimidazoles. Sanofi Aventis, Alonso Jorge, Lindenschmidt Andreas, Nazaré Marc, Halland Nis, Rkyek Omar, Urmann Matthias, THEN Johann, January 24, 2008: WO/2008/009348 (12 worldwide citation)

The present invention relates to a process for the regioselective synthesis of compounds of the formula (I), wherein RO; R1; R2; R3; R4; R5; A1; A2; A3; A4, Q and J have the meanings indicated in the claims. The present invention provides a direct palladium catalyzed, regioselective process to a wid ...


5
Alonso Jorge, Lindenschmidt Andreas, Nazaré Marc, Urmann Matthias, Halland Nis, R Kyek Omar: A regioselective copper catalyzed synthesis of benzimidazoles and azabenzimidazoles. Sanofi Aventis, Alonso Jorge, Lindenschmidt Andreas, Nazaré Marc, Urmann Matthias, Halland Nis, R Kyek Omar, THEN Johann, December 31, 2008: WO/2009/000413 (9 worldwide citation)

The present invention relates to a process for the regioselective synthesis of compounds of the formula (I), wherein R0; R1; R2; R3; R4; R5; A1; A2; A3; A4; Q and J have the meanings indicated in the claims. The present invention provides a direct copper catalyzed regioselective process to a wide va ...


6
Lindenschmidt Andreas, Will David William, Jaehne Gerhard, Wollmann Theodor Andreas, Frick Wendelin, Junker Bernd, Rigal David, Billen Guenter, Jendralla Heiner: (De) Verfahren zur herstellung von 1,4-diphenylazetidinon-derivaten, (En) Method for producing 1,4-diphenyl azetidinone derivatives. Sanofi Aventis Deutschland, Lindenschmidt Andreas, Will David William, Jaehne Gerhard, Wollmann Theodor Andreas, Frick Wendelin, Junker Bernd, Rigal David, Billen Guenter, Jendralla Heiner, December 1, 2005: WO/2005/113496 (7 worldwide citation)

(EN) The invention relates to a method for producing 1,4-diphenyl azetidinone derivatives from suitably protected $g(b)-substituted amino amides, in the presence of silylation agents. Said method uses cyclization catalysts that comprise phosphonium ions as the cation of formula (XII), and ions of th ...


7
R Kyek Omar, Nazarè Marc, Lindenschmidt Andreas, Urmann Matthias, Halland Nis, Alonso Jorge: A process for the palladium-catalyzed coupling of terminal alkynes with aryl tosylates. Sanofi Aventis, R Kyek Omar, Nazarè Marc, Lindenschmidt Andreas, Urmann Matthias, Halland Nis, Alonso Jorge, THEN Johann, January 8, 2009: WO/2009/003589 (1 worldwide citation)

The present invention relates to a process for the regioselective synthesis of compounds of the formula (I), wherein R1; R2; R3; R4; R5; J and W have the meanings indicated in the claims. The present invention provides an efficient and general palladium-catalyzed coupling process for aryl tosylates ...


8
Jaehne Gerhard, Frick Wendelin, Lindenschmidt Andreas, Heuer Hubert, Schaefer Hans Ludwig, Kramer Werner, Schmider Wolfgang: (De) Hydroxy-substituierte diphenylazetidinone zur behandlung von hyperlipidämie, (En) Hydroxy-substituted diphenylazetidinones for the treatment of hyperlipidaemia. Sanofi Aventis Deutschland, Jaehne Gerhard, Frick Wendelin, Lindenschmidt Andreas, Heuer Hubert, Schaefer Hans Ludwig, Kramer Werner, Schmider Wolfgang, May 31, 2007: WO/2007/059871

(EN) The invention relates to compounds of the formula (I) in which R1, R2, R3, R4, R5 and R6 are defined as specified, and to their physiologically compatible salts. The compounds are suitable, for example, as hypolipidaemic drugs.(DE) Die Erfindung betrifft Verbindungen der Formel (I), worin R1, R ...


9
KLINGLER Otmar, BLUM Horst, LINDENSCHMIDT Andreas, MATTER Hans: Peptides cycliques, leur préparation et leur utilisation comme inhibiteurs de ladhésion des plaquettes, Cyclic peptides, their preparation and their use as inhibitors of the platelet adhesion. Sanofi, KLINGLER Otmar, BLUM Horst, LINDENSCHMIDT Andreas, MATTER Hans, KUJATH Eckard, February 2, 2012: WO/2012/013709

The present invention relates to compounds of the Formula (I), in which R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13, R14, R15, R16, R17, R18, X1, X2, X3 and X4 have the meanings indicated in the claims, and which are valuable pharmacologically active compounds. They are reversible inhibit ...


10