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Levy Odile Esther, Hanley Michael R, Jodka Carolyn M, Lewis Diana Y, Soares Christopher J, Ghosh Soumitra S, D Souza Lawrence J, Parkes David G, Mack Christine M: Hybrid polypeptides with selectable properties. Amylin Pharmaceuticals, Levy Odile Esther, Hanley Michael R, Jodka Carolyn M, Lewis Diana Y, Soares Christopher J, Ghosh Soumitra S, D Souza Lawrence J, Parkes David G, Mack Christine M, MARSH David R, August 25, 2005: WO/2005/077072 (19 worldwide citation)

The present invention relates generally to novel, selectable hybrid polypeptides useful as agents for the treatment and prevention of metabolic diseases and disorders which can be alleviated by control plasma glucose levels, insulin levels, and/or insulin secretion, such as diabetes and diabetes-rel ...


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Ghosh Soumitra Shankar, Lewis Diana Y, Janssen Samuel, Srivastava Ved, Liu Que, Jodka Carolyn M, Soares Christopher J, Lin Qing: Composition and methods for treatment of congestive heart failure. Amylin Pharmaceuticals, Ghosh Soumitra Shankar, Lewis Diana Y, Janssen Samuel, Srivastava Ved, Liu Que, Jodka Carolyn M, Soares Christopher J, Lin Qing, BUTLER James E, December 6, 2007: WO/2007/139941 (6 worldwide citation)

Provided herein is the use of GLP-1 molecules or agonists and analogs thereof, and the use of exendin molecules or agonists and analogs thereof, including their derivatives and active fragments, for the prevention or treatment of congestive heart failure. Pharmaceutical compositions for use in the m ...