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Andries Koenraad Jozef Lodewijk Marcel, Göhlmann Hinrich Wilhelm Helmut, Neefs Jean Marc Edmond Fernand Marie, Verhasselt Peter Karel Maria, Winkler Johann, de, Jonge Marc René, Koymans Lucien Maria Henricus: A bacterial atp synthase binding domain. Janssen Pharmaceutica, Andries Koenraad Jozef Lodewijk Marcel, Göhlmann Hinrich Wilhelm Helmut, Neefs Jean Marc Edmond Fernand Marie, Verhasselt Peter Karel Maria, Winkler Johann, de, Jonge Marc René, Koymans Lucien Maria Henricus, JANSSEN PHARMACEUTICA, April 6, 2006: WO/2006/035051 (5 worldwide citation)

This invention provides an isolated mutant atpE protein and departing from said mutant atpE protein the identification of an ATPase binding domain. This invention also provides related nucleic acids, vectors, host cells, pharmaceutical compositions and articles of manufacture. This invention further ...


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De, Corte Bart, de, Jonge Marc René, Heeres Jan, Ho Chih Yung, Janssen Paul Adriaan Jan, Kavash Robert W, Koymans Lucien Maria Henricus, Kukla Michael Joseph, Ludovici Donald William, Van, Aken Koen Jeanne Alfons: Hiv replication inhibiting pyrimidines. Janssen Pharmaceutica, de, Corte Bart, de, Jonge Marc René, Heeres Jan, Ho Chih Yung, Janssen Paul Adriaan Jan, Kavash Robert W, Koymans Lucien Maria Henricus, Kukla Michael Joseph, Ludovici Donald William, Van, Aken Koen Jeanne Alfons, BOULT WADE TENNANT, May 18, 2000: WO/2000/027825 (2 worldwide citation)

This invention concerns the use of compounds of formula (I), the $i(N)-oxides, the pharmaceutically acceptable addition salts, quaternary amines and the stereochemically isomeric forms thereof, wherein -a?1¿=a?2¿=a?3¿=a?4¿- forms a phenyl, pyridinyl, pyrimidinyl, pyridazinyl or pyrazinyl with the at ...


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