1
Taichiro Akiyama: Plug-type hearing device. Koken, McDougall Hersh & Scott, January 9, 1979: US04133984 (102 worldwide citation)

A plug-type hearing device comprising a sound-leading portion being inserted into the auditory miatus, a first envelope attached around the sound-leading portion, a second envelope being positioned at the outside of the auditory miatus and being communicated with the first envelope through a pipe, a ...


2
Yasuharu Noishiki, Kazuhiko Kodaira, Masayasu Furuse, Teruo Miyata: Method of preparing antithrombogenic medical materials. Koken, Armstrong Nikaido Marmelstein & Kubovcik, February 21, 1989: US04806595 (97 worldwide citation)

In a method of preparing an antithrombogenic medical material having a heparinized collagen as an antithrombogenic component, there is provided a method comprising the steps of fixing a protamine to a collagen through a polyepoxy compound, and heparinizing the collagen by fixing heparin to the prota ...


3
Norimasa Koseki, Akihiko Sano: Sustained release formulation. Sumitomo Pharmaceuticals Company, Koken, Birch Stewart Kolasch & Birch, July 13, 1999: US05922356 (94 worldwide citation)

The present invention relates to a sustained release formulation used for treatment or prevention of the diseases, which contains a therapeutically effective substance as an active ingredient, collagen as a drug carrier, and glycosaminoglycan as an additive. The formulation allows controlled release ...


4
Taichiro Akiyama, Fumio Wada: Impermeable laminate membrane. Koken, Wegner & Bretschneider, November 8, 1983: US04413359 (94 worldwide citation)

An impermeable laminated membrane, constructed by the superposition of a silicone rubber membrane on a fluoro-rubber membrane, is disclosed.


5
Kazuhiro Noda: Operation balloon. Koken, Sherman & Shalloway, December 30, 2003: US06669711 (91 worldwide citation)

A surgical balloon which is provided with a plurality of balloons so that a fixing property and a shielding property are simultaneously satisfied, and prevents a liquid or a gas from flowing from one area in the body to another area thereof. The surgical balloon is further provided with a balloon fi ...


6
Teruo Miyata, Taichiro Akiyama, Masayasu Furuse: Artificial bone. Koken, Edward J Mahler, February 9, 1982: US04314380 (83 worldwide citation)

Artificial bone is prepared from animal bone treated for removal of organics, burned, baked and immersed in atelocollagen solution.


7
Taichiro Akiyama, Haruomi Muto: Catheter apparatus with occlusion and flow diverting means. Koken, McDougall Hersh & Scott, February 6, 1979: US04137906 (78 worldwide citation)

A catheter apparatus with occlusion and flow diverting valve means for controlling the flow of fluid into a tube including a conduit to lead fluid into cylindrical tube, a bag-like member made of resilient material and arranged to close an opening of the top of the conduit, a valve means provided on ...


8
Teruo Miyata, Kazuhiko Kodaira, Masayasu Furuse, Yasuharu Noishiki: Hemostatic agent composed of collagen/gelatin and protamine. Koken, Sherman and Shalloway, June 7, 1988: US04749689 (74 worldwide citation)

This invention relates to a hemostatic agent used in surgical operations, which can be produced in two ways: one blending collagen/gelatin with protamine, the other blending collagen/gelatin with protamine and a bi-functional cross-linking agent so as to make said collagen/gelatin have a covalent bo ...


9
Eisaburo Imamura, Yasuharu Noishiki, Hitoshi Koyanagi, Teruo Miyata, Masayasu Furuse: Bioprosthetic valve. Koken, Varndell Legal Group, January 14, 1992: US05080670 (62 worldwide citation)

A bioprosthetic valve made from a biological tissue containing collagen which has been cross-linked with a polyepoxy compound is disclosed. The valve has excellent biocompatibility and is durable and is free from calcification.


10
Yasuharu Noishiki, Teruo Miyata: Medical materials. Koken, Armstrong Nikaido Marmelstein & Kubovcik, November 3, 1987: US04704131 (59 worldwide citation)

The medical material contains heparinized collagen in which heparin has been bonded to protamine covalently fixed on collagen, and, owing to its excellent compatibility with living bodies, especially, its superb antithrombotic property, can be suitably used as a substituent material for tissues or o ...