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Ren Pingda, Wang Xia, Jiang Songchun, Nagle Advait, Okram Barun, He Yun, Xie Yongping, Wang Xing, Huang Shenlin, Wang Xiaodong, Liu Yi, Albaugh Pamela A, Gray Nathanael S, Zhang Guobao: Protein kinase inhibitors and methods for using thereof. Irm, Ren Pingda, Wang Xia, Jiang Songchun, Nagle Advait, Okram Barun, He Yun, Xie Yongping, Wang Xing, Huang Shenlin, Wang Xiaodong, Liu Yi, Albaugh Pamela A, Gray Nathanael S, Zhang Guobao, RAYMOND Daniel E, November 27, 2008: WO/2008/144253 (43 worldwide citation)

The invention provides compounds of formula (l) and pharmaceutical compositions thereof, which are useful as protein kinase inhibitors, and methods for using such compounds to treat, ameliorate or prevent a condition associated with abnormal or deregulated kinase activity. In some embodiments, the i ...


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Ren Pingda, Gray Nathanael S, Wang Xia, Zhang Guobao, Sim Taebo, Jiang Songchun: Compounds and compositions as protein kinase inhibitors. Irm, Ren Pingda, Gray Nathanael S, Wang Xia, Zhang Guobao, Sim Taebo, Jiang Songchun, REID Scott W, November 23, 2006: WO/2006/124731 (20 worldwide citation)

The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal act ...


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Albaugh Pamela A, He Yun, Jiang Songchun, Ren Pingda, Wang Xia, Wang Xing, Xie Yongping: [4,5]bipyrimidinyl-6,4-diamine derivatives as protein kinase inhbitors. Irm, Albaugh Pamela A, He Yun, Jiang Songchun, Ren Pingda, Wang Xia, Wang Xing, Xie Yongping, MCNALLY Lydia T, January 17, 2008: WO/2008/008747 (17 worldwide citation)

The invention provides a novel class of compounds of the Formula (I): in which the symbols have the meanings given in the description and claims, to pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abn ...


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Chianelli Donatella, Cow Christopher, He Yun, Jiang Songchun, Li Xiaolin, Liu Xiaodong, Liu Zuosheng, Loren Jon, Molteni Valentina, Nabakka Juliet, Ren Pingda, Sim Taebo, Wang Xiaodong, You Shuli: Compositions and methods for modulating c-kit and pdgfr receptors. Irm, Chianelli Donatella, Cow Christopher, He Yun, Jiang Songchun, Li Xiaolin, Liu Xiaodong, Liu Zuosheng, Loren Jon, Molteni Valentina, Nabakka Juliet, Ren Pingda, Sim Taebo, Wang Xiaodong, You Shuli, TONGCO WU Emily, May 2, 2008: WO/2008/051757 (11 worldwide citation)

The invention provides compounds and pharmaceutical compositions thereof, which are useful as protein kinase inhibitors, as well as methods for using such compounds to treat, ameliorate or prevent a condition associated with abnormal or deregulated kinase activity. In some embodiments, the invention ...


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Azimioara Mihai, Cow Christopher, Epple Robert, Jiang Songchun, Lelais Gerald, Mutnick Daniel, Wu Baogen: Compounds and compositions as modulators of gpr119 activity. Irm, Azimioara Mihai, Cow Christopher, Epple Robert, Jiang Songchun, Lelais Gerald, Mutnick Daniel, Wu Baogen, REID Scottet al, August 27, 2009: WO/2009/105717 (11 worldwide citation)

The invention provides compounds of Formula (I): pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of GPR119.


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Sim Taebo, Gray Nathanael Schiander, Lee Hyun Soo, Liu Yi, Ren Pingda, You Shuli, Zhang Qiong, Ding Qiang, Wang Xia, Jiang Songchun, Albaugh Pamela A: Compounds and compositions as protein kinase inhibitors. Irm, Sim Taebo, Gray Nathanael Schiander, Lee Hyun Soo, Liu Yi, Ren Pingda, You Shuli, Zhang Qiong, Ding Qiang, Wang Xia, Jiang Songchun, Albaugh Pamela A, REID Scott W, August 3, 2006: WO/2006/081172 (7 worldwide citation)

The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal act ...


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Alper Phillip, Azimioara Mihai, Cow Christopher, Epple Robert, Jiang Songchun, Lelais Gerald, Michellys Pierre Yves, Nguyen Truc Ngoc, Westcott Baker Lucas, Wu Baogen: Compounds and compositions as modulators of gpr119 activity. Irm, Alper Phillip, Azimioara Mihai, Cow Christopher, Epple Robert, Jiang Songchun, Lelais Gerald, Michellys Pierre Yves, Nguyen Truc Ngoc, Westcott Baker Lucas, Wu Baogen, REID Scott, August 14, 2008: WO/2008/097428 (6 worldwide citation)

The invention provides compounds, pharmaceutical compositions comprising compound of following formula (I), and methods of using such compounds to treat or prevent diseases or disorders associated with theactivity of GPR119 (G protein-coupled receptor 119) such as obesity, diabetes and hyperlipidemi ...


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Cai Sui Xiong, Sirisoma Nilantha Sudath, Pervin Azra, Drewe John A, Kasibhatla Shailaja, Jiang Songchun, Zhang Hong, Pleiman Chris, Baichwal Vijay, Manfredi John, Bhoite Leena: 4-arylamino-quinazolines as activators of caspases and inducers of apoptosis. Myriad Genetics, Cytovia, Cai Sui Xiong, Sirisoma Nilantha Sudath, Pervin Azra, Drewe John A, Kasibhatla Shailaja, Jiang Songchun, Zhang Hong, Pleiman Chris, Baichwal Vijay, Manfredi John, Bhoite Leena, ZHANG Jay Z, January 13, 2005: WO/2005/003100 (4 worldwide citation)

Disclosed are 4-arylamino-quinazolines and analogs thereof effective as activators of caspases and inducers of apoptosis. The compounds of this invention are useful in the treatment of a variety of clinical conditions in which uncontrolled growth and spread of abnormal cells occurs.


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Cai Sui Xiong, Anderson Mark B, Willardsen Adam, Jiang Songchun, Halter Robert J, Slade Rachel, Klimova Yevgeniya: Pharmaceutical compounds as activators of caspases and inducers of apoptosis and the use thereof. Myriad Genetics, Cytovia, Cai Sui Xiong, Anderson Mark B, Willardsen Adam, Jiang Songchun, Halter Robert J, Slade Rachel, Klimova Yevgeniya, GIBBS Andrew, July 13, 2006: WO/2006/074223 (1 worldwide citation)

Disclosed are 1-arylamino-phthalazines, 4-arylamino-benzo[d][1,2,3]triazines, and analogs thereof effective as activators of caspases and inducers of apoptosis. The compounds of this invention are useful in the treatment of a variety of clinical conditions in which uncontrolled growth and spread of ...