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Dai Mingshi, Jenkins Tracy J, Guan Bing, Ghosh Shomir, Minor Charles: Ccr8 inhibitors. Millennium Pharmaceuticals, Dai Mingshi, Jenkins Tracy J, Guan Bing, Ghosh Shomir, Minor Charles, DAVIS Steven G, July 15, 2004: WO/2004/058736 (11 worldwide citation)

Disclosed is an inhibitor of CCR8 that is represented by Structural Formula (I). Also disclosed are pharmaceutical compositions comprising a pharmaceutically acceptable carrier or diluent and a CCR8 inhibitor represented by Structural Formula (I). Also disclosed is a method of treating inflammatory ...


2
Guan Bing, Minor Charles, Dai Mingshi, Ghosh Shomir, Jenkins Tracy J, Li Gang, Burdi Douglas F, Bennett Robert A: Ccr8 inhibitors. Millennium Pharmaceuticals, Guan Bing, Minor Charles, Dai Mingshi, Ghosh Shomir, Jenkins Tracy J, Li Gang, Burdi Douglas F, Bennett Robert A, DAVIS Steven G HAMILTON BROOK SMITH HAMILTON BROOK SMITH & REYNOLDS PC 530 Virginia Road PO Box 9133 Concord Massachusetts 01742 9133, July 15, 2004: WO/2004/058709 (10 worldwide citation)

Disclosed are CCR8 inhibitors represented by Structural Formulas (I). The variables in Structural Formula (I) are described herein. Also disclosed are methods of treating a subject with a CCR8 mediated condition, especially asthma, by administering one of the disclosed CCR8 inhibitors to the subject ...


3
HOPKINS Brian T, SCOTT Daniel, CONLON Patrick, JENKINS Tracy J, POWELL Noel, GUAN Bing, CUERVO Julio H, WANG Deping, TAVERAS Art: INHIBITEURS DE TYROSINE KINASE HÉTÉROCYCLIQUES, HETEROCYCLIC TYROSINE KINASE INHIBITORS. BIOGEN IDEC MA, SUNESIS PHARMACEUTICALS, HOPKINS Brian T, SCOTT Daniel, CONLON Patrick, JENKINS Tracy J, POWELL Noel, GUAN Bing, CUERVO Julio H, WANG Deping, TAVERAS Art, REARICK John P, May 3, 2012: WO/2012/058645 (5 worldwide citation)

The present invention provides compounds useful as inhibitors of Tec family kinases, compositions thereof, and methods of using the same. In certain embodiments, the present invention provides pharmaceutical formulations comprising provided compounds. In certain embodiments, the present invention pr ...


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Ghosh Shomir, Patane Michael A, Carson Kenneth G, Chi I Cheng Shannon, Ye Qing, Elder Amy M, Jenkins Tracy J: Compounds, pharmaceutical compositions and methods of use therefor. Millennium Pharmaceuticalsinc, Ghosh Shomir, Patane Michael A, Carson Kenneth G, Chi I Cheng Shannon, Ye Qing, Elder Amy M, Jenkins Tracy J, CARROLL Alice O, May 8, 2003: WO/2003/037271 (2 worldwide citation)

The invention relates to compounds having the formula (I). Preferred compounds are antagonists of C-C chemokine receptor 8. The invention also relates to a method for treating a subjected having an inflammatory disorder or viral disorder comprising administering to a subject in need thereof an effec ...