1
Nikolaas C J de Jaeger, Marcel J Monbaliu, Marcus J M Noppe, Frank J Konings: Immunoassay using colorable latex particles. Janssen Pharmaceutica, June 6, 1989: US04837168 (140 worldwide citation)

New method for the detection of specific binding agents and their corresponding bindable substances by employing a label which is a latex particle which can be visually detected.


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Imogai Hassan Julien, Duvey Guillaume Albert Jacques, Cid Núñez José Maria, Lütjens Robert Johannes, Le, Poul Emmanuel Christian: Novel thieno-pyridine and thieno-pyrimidine derivatives and their use as positive allosteric modulators of mglur2-receptors. Janssen Pharmaceutica, Addex Pharmaceuticals, Imogai Hassan Julien, Duvey Guillaume Albert Jacques, Cid Núñez José Maria, Lütjens Robert Johannes, Le, Poul Emmanuel Christian, CAMPBELL Neil, March 23, 2006: WO/2006/030031 (119 worldwide citation)

The present invention relates to novel compounds, in particular novel thieno-pyridine and thieno-pyrimidine derivatives according to Formula (I), wherein all radicals are defined in the application. The compounds according to the invention are positive allosteric modulators of metabotropic receptors ...


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Vandenberk Jan, Kennis Ludo Edmond Josephine, Van Der Aa Marcel Josef Maria, Van Heertum Albert Henricus Ma: (Piperidinylalkyl)Quinazoline derivatives, process for their preparation and pharmaceutical compositions containing them.. Janssen Pharmaceutica, July 23, 1980: EP0013612-A2 (108 worldwide citation)

Quinazoline derivatives of the formula wherein Ra is hydrogen or alkyl and and q is 2 or 3; R is hydorgen, hydroxy and alkyl; Alk is an alkylene chain having from 1 to 4 carbon atoms and Q is a quinazolinyl radical, the 1-, 2-, 3- or 4-position of which is connected with the alkylene side chain, sai ...


5
Van Daele Georges: Novel n-(3-hydroxy-4-piperidinyl)benzamide derivatives.. Janssen Pharmaceutica, April 13, 1983: EP0076530-A2 (107 worldwide citation)

Novel N-(4-piperidinyl)benzamides of the formula and the pharmaceutically acceptable acid addition salts, the stereochemically isomeric forms and the pharmaceutically acceptable quaternary ammonium salts thereof, which compounds are useful as stimulators of the motility of the gastro-intestinal syst ...


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Stokbroekx Raymond Antoine, Grauwels Gilbert Arthur Jules, Willems Marc: Antirhinoviral piperidinyl, pyrrolidinyl and piperazinyl alkylphenol ethers.. Janssen Pharmaceutica, November 22, 1990: EP0398425-A1 (91 worldwide citation)

Piperidinyl, pyrrolidinyl and piperazinyl alkylphenol ethers of formula X is N or CH; Alk is C1-4alkanediyl; R and R are hydrogen, C1-4alkyl or halo; R is hydrogen, halo, cyano, C1-4alkyloxy, aryl or -COOR, with R being hydrogen, C1-4alkyl, arylC1-4alkyl, C3-6cycloalkylC1-4alkyl, C3-5alkenyl, C3-5al ...


8
Bernd W W Muller: Derivatives of gamma-cyclodextrin. Janssen Pharmaceutica, Geoffrey G Dellenbaugh, August 16, 1988: US04764604 (89 worldwide citation)

This invention relates to .gamma.-cyclodextrin ethers and mixed ethers wherein the ether substituents are C.sub.1 -C.sub.6 alkyl, hydroxy C.sub.1 -C.sub.6 alkyl, carboxy C.sub.1 -C.sub.6 alkyl or (C.sub.1 -C.sub.6 alkyloxycarbonyl) C.sub.1 -C.sub.6 alkyl; provided that hydroxypropyl is not a sole su ...


9
Andries Koenraad Jozef L M, Corte Bart de, Jonge Marc Rene de, Heeres Jan, Ho Chih Yung, Janssen Marcel August Constant, Janssen Paul Adriaan Jan, Koymans Lucien Maria Henricus, Kukla Michael Joseph, Ludovici Donald William, Aken Koen Jeanne Alfons Van: Hiv inhibiting pyrimidine derivatives. Janssen Pharmaceutica, September 29, 1999: EP0945443-A1 (86 worldwide citation)

This invention concerns the use of the compounds of formula the N-oxides, the pharmaceutically acceptable addition salts and the stereochemically isomeric forms thereof, wherein A is CH, CR or N; n is 0 to 4; Q is hydrogen or -NRR; R and R are selected from hydrogen, hydroxy, C1-12alkyl, C1-12alkylo ...


10
Ludo E J Kennis, Jan Vandenberk: 3-piperidinyl-substituted 1,2-benzisoxazoles and 1,2-benzisothiazoles. Janssen Pharmaceutica, February 14, 1989: US04804663 (82 worldwide citation)

3-Piperdinyl-1,2-benzisothiazoles and 3-piperidinyl-1,2-benzisoxazoles and their pharmaceutically acceptable acid addition salts having useful antipsychotic properties and being useful in the treatment of a variety of complaints in which serotonin release is of predominant importance.



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