1
Darrell R Anderson, Nabil Hanna, John E Leonard, Roland A Newman, Mitchell E Reff, William H Rastetter: Therapeutic application of chimeric and radiolabeled antibodies to human B lymphocyte restricted differentiation antigen for treatment of B cell lymphoma. Idec Pharmaceuticals Corporation, Burns Doane Swecker & Mathis, April 7, 1998: US05736137 (387 worldwide citation)

Disclosed herein are therapeutic treatment protocols designed for the treatment of B cell lymphoma. These protocols are based upon therapeutic strategies which include the use of administration of immunologically active mouse/human chimeric anti-CD20 antibodies, radiolabeled anti-CD20 antibodies, an ...


2
Roland A Newman, Nabil Hanna, Ronald W Raab: Recombinant antibodies for human therapy. Idec Pharmaceuticals Corporation, Burns Doane Swecker & Mathis, August 19, 1997: US05658570 (189 worldwide citation)

Chimeric antibodies including an Old World monkey portion and a human portion, nucleic acid encoding such antibodies, Old World monkey monoclonal antibodies, and methods for their production and use.


3
Darrell R Anderson, Nabil Hanna, John E Leonard, Roland A Newman, Mitchell E Reff, William H Rastetter: Therapeutic application of chimeric and radiolabeled antibodies to human B lymphocyte restricted differentiation antigen for treatment of B cell lymphoma. IDEC Pharmaceuticals Corporation, Burns Doane Swecker & Mathis, July 7, 1998: US05776456 (187 worldwide citation)

Disclosed herein are therapeutic treatment protocols designed for the treatment of B cell lymphoma. These protocols are based upon therapeutic strategies which include the use of administration of immunologically active mouse/human chimeric anti-CD20 antibodies, radiolabeled anti-CD20 antibodies, an ...


4
Antonio J Grillo López: Combination therapies for B-cell lymphomas comprising administration of anti-CD20 antibody. IDEC Pharmaceuticals Corporation, Robin L Teskin, September 24, 2002: US06455043 (127 worldwide citation)

New combined therapeutic regimens for treatment of B-cell lymphomas are disclosed which comprise in particular administration of anti-CD20 antibodies to patients having low-, intermediate- or high-grade non-Hodgkins lymphomas.


5
Roland A Newman, Nabil Hanna, Ronald W Raab: Recombinant antibodies for human therapy. IDEC Pharmaceuticals Corporation, Burns Doane Swecker & Mathis, May 12, 1998: US05750105 (114 worldwide citation)

Chimeric antibodies including an Old World monkey portion and a human portion, nucleic acid encoding such antibodies, Old World monkey monoclonal antibodies, and methods for their production and use.


6
Darrell R Anderson, Peter Brams, Nabil Hanna, William S Shestowsky, Cheryl Heard: Human B7.1-specific primatized antibodies and transfectomas expressing said antibodies. IDEC Pharmaceuticals Corporation, Burns Doane Swecker & Mathis, September 5, 2000: US06113898 (80 worldwide citation)

The present invention relates to the identification of macaque antibodies to human B7.1 and B7.2 by screening of phage display libraries or monkey heterohybridomas obtained using B lymphocytes from B7.1 and/or B7.2 immunized monkeys. More specifically, the invention provides four monkey monoclonal a ...


7
Peter Brams, Soulaima Salim Chamat, Li Zhen Pan, Edward E Walsh, Cheryl Janne Heard, Roland Anthony Newman: Neutralizing high affinity human monoclonal antibodies specific to RSV F-protein and methods for their manufacture and therapeutic use thereof. IDEC Pharmaceuticals Corporation, Burns Doane Swecker & Mathis, September 22, 1998: US05811524 (79 worldwide citation)

A highly efficient method for generating human antibodies in particular which are specific to be RSV fusion protein which combines in vitro priming of human spleen cells and antigen boosting in SCID mice is taught. This method provides for very high human antibody titers which are predominantly of t ...


8
Roland A Newman, Nabil Hanna, Ronald W Raab: Recombinant antibodies for human therapy. Idec Pharmaceuticals Corporation, Burns Doane Swecker & Mathis, December 2, 1997: US05693780 (79 worldwide citation)

Chimeric antibodies including an Old World monkey portion and a human portion, nucleic acid encoding such antibodies, Old World monkey monoclonal antibodies, and methods for their production and use.


9
Nabil Hanna, Roland Anthony Newman, Mitchell Elliot Reff: Recombinant anti-CD4 antibodies for human therapy. IDEC Pharmaceuticals Corporation, Burns Doane Swecker & Mathis, October 24, 2000: US06136310 (62 worldwide citation)

Chimeric antibodies specific to human CD4 antigen, DNA encoding, pharmaceutical compositions containing and use thereof as therapeutic agents are taught. These chimeric antibodies contain Old World monkey variable sequences and human constant domain sequences, preferably human gamma 1, gamma 4 or mu ...


10
Roland A Newman, Nabil Hanna, Ronald W Raab: Recombinant antibodies for human therapy. IDEC Pharmaceuticals Corporation, Burns Doane Swecker & Mathis L, May 26, 1998: US05756096 (55 worldwide citation)

Chimeric antibodies including an Old World monkey portion and a human portion, nucleic acid encoding such antibodies, Old World monkey monoclonal antibodies, and methods for their production and use.