1
Guo Feng Xu: Biological artificial ligament and method of making. Grandhope Biotech, Raymond Sun, March 9, 2010: US07674289 (5 worldwide citation)

A prosthesis for implantation into a human body is made by a method that includes the steps of providing a natural animal ligament or tendon that has a substrate, crosslinking and fixing the substrate, minimizing the antigens from the substrate, tanning the substrate to improve its mechanical proper ...


2
Guo Feng Xu: Biological wound dressing and method of making. Grandhope Biotech, Raymond Sun, October 26, 2010: US07820871 (5 worldwide citation)

A biological wound dressing is made by a method that includes the steps of providing a natural animal tissue that has a substrate, crosslinking and fixing the substrate, minimizing the antigens from the substrate, and incorporating an active layer in the substrate.


3
Guo Feng Xu: Biological artificial blood vessel and method of making. Grandhope Biotech, Raymond Sun, October 23, 2012: US08292799 (4 worldwide citation)

A prosthetic device for implantation into a human body is made by a method that includes the steps of providing a natural animal tissue that has a substrate, crosslinking and fixing the substrate, minimizing the antigens from the substrate, tanning the substrate to improve its mechanical properties, ...


4
Guo Feng Xu: Biological artificial ligament and method of making. Grandhope Biotech, Raymond Sun, November 2, 2010: US07824447 (4 worldwide citation)

A prosthesis for implantation into a human body is made by a method that includes the steps of providing a natural animal ligament or tendon that has a substrate, crosslinking and fixing the substrate, minimizing the antigens from the substrate, tanning the substrate to improve its mechanical proper ...


5
Guo Feng Xu: Biological artificial nerve guide and method of making. Grandhope Biotech, Raymond Sun, November 17, 2009: US07618653 (3 worldwide citation)

A biological nerve guide for implantation into a human body is made by providing a natural animal tissue membrane, crosslinking and fixing the membrane, minimizing the antigens from the membrane, tanning the membrane, coupling an active layer to an inner surface of the membrane, cutting the membrane ...


6
XU GUOFENG: Jawbone prosthesis and manufacturing method thereof. GRANDHOPE BIOTECH, Advance China I P Law Office, May 20, 2010: WO/2010/054527 (1 worldwide citation)

A biological jawbone prosthesis is made according to a method that includes the steps of collecting animal material from a bovine or porcine source, the animal material being a jawbone, shaping the animal material to provide a desired shape for the jawbone implant, removing cells from the animal mat ...


7
Guo Feng Xu: Biological artificial nerve guide and method of making. Grandhope Biotech, Raymond Sun, February 5, 2013: US08366770

A biological nerve guide for implantation into a human body is made by providing a natural animal tissue membrane, crosslinking and fixing the membrane, minimizing the antigens from the membrane, tanning the membrane, coupling an active layer to an inner surface of the membrane, cutting the membrane ...


8
Song Tao Qi, Guo Feng Xu: Biological membrane-carrying aneurysm clip. Grandhope Biotech, Raymond Sun, June 12, 2012: US08197500

An aneurysm clip has a biological membrane and a metal clip. The membrane is harvested from an animal, crosslinked, and then has its antigens minimized. The membrane also has an active layer coupled thereto. The metal clip has a first clip bar and a second clip bar that are attached to each in a bia ...


9
Guo Feng Xu: Biological surgical patch and method of making. Grandhope Biotech, Raymond Sun, January 24, 2012: US08100970

A biological surgical patch made by a method that includes the steps of providing a natural animal tissue that has a substrate, crosslinking and fixing the substrate, minimizing the antigens from the substrate, tanning the substrate, and incorporating an active layer in the substrate.


10
Yang Jun: Methode permettant la fixation de tissus au moyen depoxydes, Method for tissue fixation using epoxides. A V Healing, Grandhope Biotech, Oyen Wiggs Green & Mutala, October 26, 2010: CA2351216

The present invention provides an epoxy compound that has a hydrocarbon backbone, that is water-soluble, and which does not contain an ether orester linkage in its backbone for use in cross-linking bioprosthetic tissue. Examples of suitable epoxide agents include mono- or diepoxides that have the fo ...