1
Mark E Smulson, Kishor Bhatia, Konrad Huppi: Method of detecting a predisposition to cancer by the use of restriction fragment length polymorphism of the gene for human poly (ADP-ribose) polymerase. Georgetown University, Sterne Kessler Goldstein & Fox, December 21, 1993: US05272057 (348 worldwide citation)

The invention relates to a method for detecting the presence of a DNA polymorphism associated with predisposition for certain cancers in a human. This method involves analyzing the human chromosome 13 using a hybridization probe which will hybridize to the gene for human poly (ADP-ribose) polymerase ...


2
Richard L Verrier, Bruce D Nearing: Method and apparatus for prediction of sudden cardiac death by simultaneous assessment of autonomic function and cardiac electrical stability. Georgetown University, Sterne Kessler Goldstein & Fox, August 1, 1995: US05437285 (284 worldwide citation)

A method and apparatus for predicting susceptibility to sudden cardiac death simultaneously assessing cardiac electrical stability and autonomic influence. Cardiac electrical stability is assessed by analyzing at least one of a beat-to-beat alternation in a T-wave of an ECG of a patient's heart and ...


3
John F Currie, Makarand Paranjape, Carl C Peck, Robert White, Thomas W Schneider: Systems and methods for monitoring health and delivering drugs transdermally. Science Applications International Corporation, Georgetown University, Kilpatrick Stockton, May 3, 2005: US06887202 (237 worldwide citation)

The present invention pertains to a system and method for transdermal sampling, comprising: at least one sampler for retrieving and transferring at least one analyte obtained transdermally from the skin of a subject; at least one detector system for identifying and quantifying said at least one anal ...


4
Richard L Verrier: Method for transvenously accessing the pericardial space via the right auricle for medical procedures. Georgetown University, Sterne Kessler Goldstein & Fox, December 14, 1993: US05269326 (146 worldwide citation)

A method for placing various types of catheters into the pericardial space takes advantage of the fact that the right auricle is a thin-walled, low-pressure structure which can be readily penetrated without damaging the pericardium or the epicardium. The method avoids surgical trauma and the risks o ...


5
Richard L Verrier, Bruce D Nearing: Method and apparatus for prediction of cardiac electrical instability by simultaneous assessment of T-wave alternans and QT interval dispersion. Georgetown University, Sterne Kessler Goldstein & Fox P L L C, October 1, 1996: US05560370 (140 worldwide citation)

A method and apparatus for predicting cardiac electrical instability simultaneously assesses T-Wave Alternans and QT Interval Dispersion. T-wave alternation is an excellent predictor of cardiac electrical instability but can be influenced by mechano-electrical coupling. Thus, a measure of alternatio ...


6
Richard L Verrier, Bruce D Nearing: Non-invasive, dynamic tracking of cardiac vulnerability by simultaneous analysis of heart rate variability and T-wave alternans. Georgetown University, Sterne Kessler Goldstein & Fox P L L C, December 1, 1998: US05842997 (107 worldwide citation)

A method and an apparatus for the non-invasive, dynamic tracking and diagnosing of cardiac vulnerability to ventricular fibrillation are disclosed. T-wave alternans and heart rate variability are simultaneously evaluated. T-wave alternation is an absolute predictor of cardiac electrical stability. H ...


7
Richard L Verrier, Bruce D Nearing: Non-invasive dynamic tracking of cardiac vulnerability by analysis of T-wave alternans. Georgetown University, Sterne Kessler Goldstein & Fox, September 22, 1992: US05148812 (104 worldwide citation)

A non-invasive method for dynamic tracking of cardiac vulnerability to ventricular fibrillation is disclosed. A heart is monitored to sense an ECG signal. The sensed ECG signal is then amplified and low-pass filtered before it is digitally sampled and stored. The location of the T-wave in each R-R i ...


8
Richard L Verrier, Bruce D Nearing: Method and apparatus for using physiologic stress in assessing myocardial electrical stability. Georgetown University, Sterne Kessler Goldstein & Fox, July 13, 1999: US05921940 (86 worldwide citation)

The non-invasive, dynamic tracking and diagnosing of cardiac vulnerability to ventricular fibrillation involves analysis of both cardiac electrical stability and the influence of autonomic activity. The magnitude of alternation in an electrocardiogram is indicative of cardiac electrical stability. A ...


9
Richard L Verrier, Bruce D Nearing: Methods and means for non-invasive, dynamic tracking of cardiac vulnerability by simultaneous analysis of heart rate variability and T-wave alternans. Georgetown University, Sterne Kessler Goldstein & Fox, November 30, 1993: US05265617 (80 worldwide citation)

A method and apparatus for the non-invasive, dynamic tracking and diagnosing of cardiac vulnerability to ventricular fibrillation are disclosed. T-wave alternans and heart rate variability are simultaneously evaluated. T-wave alternation is an absolute predictor of cardiac electrical instability. He ...


10
Robert S Ledley, Thomas J Golab, Michael Buas: Computerized electro-oculographic (CEOG) system with feedback control of stimuli. Georgetown University, Oblon Fisher Spivak McClelland & Maier, October 2, 1984: US04474186 (74 worldwide citation)

A computerized electro-oculographic (CEOG) system with feedback control of test stimuli comprises an integrated system for automated administration of electro-oculographic tests and visual evoked response tests to a patient, automated processing of the results derived from such tests, and automated ...