1
Stephen A Boppart, Gary J Tearney, Brett E Bouma, Mark E Brezinski, James G Fujimoto, Eric A Swanson: Methods and apparatus for forward-directed optical scanning instruments. The General Hospital Corporation, Testa Hurwitz & Thibeault, November 26, 2002: US06485413 (683 worldwide citation)

An imaging system for performing forward scanning imaging for application to therapeutic and diagnostic devises used in medical procedures. The imaging system includes forward directed optical coherence tomography (OCT), and non-retroreflected forward scanning OCT. Also interferometric imaging and r ...


2
Nikiforos Kollias, Wei Dong Tian, Jenny E Freeman: Non-invasive tissue glucose level monitoring. The General Hospital Corporation, Kristofer E Elbing, January 7, 2003: US06505059 (505 worldwide citation)

Instruments and methods for performing non-invasive measurements of analyte concentrations and for monitoring, analyzing and regulating tissue status, such as tissue glucose levels.


3
Nikiforos Kollias, Wei Dong Tian, Jenny E Freeman: Non-invasive tissue glucose level monitoring. The General Hospital Corporation, Kristofer E Elbing, April 27, 2004: US06728560 (499 worldwide citation)

Instruments and methods for performing non-invasive measurements of analyte concentrations and for monitoring, analyzing and regulating tissue status, such as tissue glucose levels.


4
Ralph Weissleder, Alexei Bogdanov: Hydrogel compositions and methods of use. The General Hospital Corporation, Fish & Richardson, May 7, 1996: US05514379 (420 worldwide citation)

Biocompatible, biodegradable, hydrogels are prepared from a backbone bonded to a cross-linking agent. Suitable backbones include proteins and polysaccharides, e.g,, albumin, polymannuronic acid, or polygalacturonic acid. Suitable cross-linking agents include polyvalent derivatives of polyethylene or ...


5
James P Welch, Nathaniel M Sims: Network for portable patient monitoring devices. The General Hospital Corporation, Fish & Richardson, June 7, 1994: US05319363 (357 worldwide citation)

Multiple devices that are each suitable for use at a selected one of multiple locations are managed using a network of links that are each assigned to one of the locations. Each link is selectable between a state in which a device is not using the link and a state in which one or more devices are us ...


6
Randall Y Grimes: Devices and methods for percutaneous mitral valve repair. The General Hospital Corporation, The Georgia Tech Research Corporation, Nutter McClennen & Fish, November 6, 2001: US06312447 (291 worldwide citation)

Devices and methods are provided for diagnosing and repairing mitral valve defects such as mitral valve regurgitation. According to an exemplary method, mitral valve function is visualized by transesophageal echocardiography. A catheter (


7
James F Gusella: Test for Huntingtons disease. The General Hospital Corporation, Saidman Sterne Kessler & Goldstein, May 19, 1987: US04666828 (290 worldwide citation)

A method for detecting the presence of the gene for Huntington's disease in a subject which comprises analyzing the human chromosome 4 of the subject for a DNA polymorphism, preferably a restriction fragment length polymorphism (RFLP), linked to Huntington's Disease.


8
Nathaniel M Sims, John M Turner, Jane M Zeisloft, Daniel C Kusswurm, Ralph H LaBedz: Managing an inventory of devices. The General Hospital Corporation, Baxter International, Fish & Richardson, July 18, 1995: US05434775 (269 worldwide citation)

The locations of a plurality of devices are tracked using a network of communication links, each of which corresponds to a location. Each device is given a tag that identifies the device with respect to other devices and that is connectable to a communication link when the device is disposed at the ...


9
Gregory B Altshuler, R Rox Anderson, Dieter Manstein: Method and apparatus for the selective targeting of lipid-rich tissues. The General Hospital Corporation, Palomar Medical Technologies, Wolf Greenfield & Sacks P C, August 12, 2003: US06605080 (248 worldwide citation)

A method and apparatus are provided for targeting lipid-rich tissue to effect a desired, the method/apparatus involving irradiating the lipid-rich tissue with energy at a wavelength preferentially absorbed by lipid cells, such wavelength being preferably in a band between 880 nm and 935 nm, 1150 nm ...


10
Gregory B Altshuler, R Rox Anderson: Method and apparatus for dermatology treatment. Palomar Medical Technologies, General Hospital Corporation, Wolf Greenfield & Sacks P C, August 14, 2001: US06273884 (228 worldwide citation)

Methods and apparatus for dermatology treatment are provided which involve the use of continuous wave (CW) radiation, preheating of the treatment volume, precooling, cooling during treatment and post-treatment cooling of the epidermis above the treatment volume, various beam focusing techniques to r ...