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Deroy Patrick, Faucher Anne Marie, Gagnon Alexandre, Landry Serge, Morin Sébastien, O Meara Jeffrey, Simoneau Bruno, Thavonekham Bounkham, Yoakim Christiane: Non nucleoside reverse transcriptase inhibitors. Boehringer Ingelheim, International, Boehringer Ingelheim, Pharma & Co Kg, Deroy Patrick, Faucher Anne Marie, Gagnon Alexandre, Landry Serge, Morin Sébastien, O Meara Jeffrey, Simoneau Bruno, Thavonekham Bounkham, Yoakim Christiane, BERNIER Louise G, December 15, 2005: WO/2005/118575 (7 worldwide citation)

The invention relates to compounds of formula (I) wherein Ar, X, R1, R2, R3 and R4 are as defined herein and pharmaceutical compositions thereof useful, either alone or in combination with other therapeutic agents as reverse transcriptase inhibitors against wild type and single or double mutant stra ...


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Yoakim Christiane, Deroy Patrick, Duplessis Martin, Gagnon Alexandre, Goulet Sylvie, Hücke Oliver, Lemke Christopher, Surprenant Simon: Inhibitors of hiv replication. Boehringer Ingelheim International, Boehringer Ingelheim, Pharma & Co Kg, Yoakim Christiane, Deroy Patrick, Duplessis Martin, Gagnon Alexandre, Goulet Sylvie, Hücke Oliver, Lemke Christopher, Surprenant Simon, LOOPER Ywe J, June 12, 2008: WO/2008/067644

The present invention relates to compounds of formula (I) wherein R1, R2, R3 and R4 are as defined herein, compositions and uses thereof for treating human immunodeficiency virus (HIV) infection. In particular, the present invention provides novel inhibitors of HIV replication, pharmaceutical compos ...


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Bonneau Pierre, Deroy Patrick, Gagnon Alexandre, O Meara Jeffrey, Simoneau Bruno, Yoakim Christiane: Alkynyl based dervatives of benzophenone as non-nucleoside reverse transcriptase inhibitors. Boehringer Ingelheim International & Co Kg, Boehringer Ingelheim Pharma & Co Kg, Bonneau Pierre, Deroy Patrick, Gagnon Alexandre, O Meara Jeffrey, Simoneau Bruno, Yoakim Christiane, LOOPER Ywe J, April 6, 2006: WO/2006/034583

Compounds of formula (I) wherein Q, R1, R2, R3, R4, R6 and R7 are as defined herein. The compounds are useful as reverse transcriptase inhibitors against HIV. In particular, the compounds are active against wild type and single or double mutant strains of HIV.


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