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Miyata Susumu, Hashimoto Michizane, Takase Shigehiro, Kiyoto Sumio, Okuhara Masakuni: Compositions with endothelin antagonist activity. Fujisawa Pharmaceutical Co, March 17, 1993: GB2259450-A (33 worldwide citation)

Pharmaceutical compositions comprise as the active ingredient, WF12880A (also known as TAN 1415A or asterric acid) of formula: and a carrier. WF12880A can be obtained by fermentation of a strain, such as Penicillium citreonigrum F-12880, in a nutrient medium. Composition has activity as a vasodilato ...


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Shima Ichiro, Kurosaki Toshio, Wada Aiko: 2-cyanopyrrolidine derivatives and their use as dpp-iv inhibitors. Fujisawa Pharmaceutical, Shima Ichiro, Kurosaki Toshio, Wada Aiko, UEKI Kyuichi, November 18, 2004: WO/2004/099185 (33 worldwide citation)

A compound of the formula (I) or a pharmaceutically acceptable salt thereof: [wherein X is CFH, or CF?2#191, R¿1? is the moiety represented by the formula: [wherein R¿2? is (lower)alkyl, R¿3? is phenyl-(lower)alkyl, and the like.], and the like.] Compounds of formula (I) inhibit DPP-IV activity. ...


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Norihiko Shimazaki, Hitoshi Yamazaki, Takumi Yatabe, Hirokazu Tanaka: Quinazoline derivatives and their preparation. Fujisawa Pharmaceutical, Oblon Spivak McClelland Maier & Neustadt, April 19, 1994: US05304560 (32 worldwide citation)

This invention relates to certain 1-heterocycloalkylquinazolin-2,3-dione derivatives, certain pharmaceutically acceptable salts thereof, the process of making those compounds, and the method of using the compounds. The compounds and compositions display effects on the peripheral or central nervous s ...


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Saburo Obata, Kazuo Ito: Applicator for aerosol-type containers. Fujisawa Pharmaceutical, Toyo Seikan Kaisha, Oblon Fisher Spivak McClelland & Maier, August 6, 1985: US04533273 (32 worldwide citation)

An applicator for an aerosol-type container having a movable nozzle projecting from its head comprises a cap and a brush attached to the cap. The cap includes, as integrally molded together, a peripheral wall fittable to the head of the container to surround the nozzle, a nozzle pushing member, and ...


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Yoshinari Sato: 6-Acyloryalkyl-1,4-dihydropyridine derivatives and a method of effecting vasodilation therewith. Fujisawa Pharmaceutical, Dayton R Stemple Jr, March 20, 1979: US04145432 (32 worldwide citation)

This invention relates to 1,4-dihydropyridine derivatives. More particularly, it relates to new 1,4-dihydropyridine derivatives thereof which have vasodilating and anti-hypertensive activity, to processes for the preparation thereof, and to pharmaceutical composition comprising the same for therapeu ...


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Yoshinari Sato, Teruaki Matuo: Benzodiazepine derivatives. Fujisawa Pharmaceutical Company, Oblon Spivak McClelland Maier & Neustadt, November 13, 1990: US04970207 (32 worldwide citation)

This invention relates to new benzodiazepine derivatives and pharmaceutically acceptable salts thereof. More particularly, it relates to new benzodiazepine derivatives and pharmaceutically acceptable salts thereof which are cholecystokinin (CCK) antagonists and therefore can be used as therapeutical ...


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Takao Takaya, Hisashi Takasugi, Takashi Masugi, Hideaki Yamanaka, Kohji Kawabata: 7-Acylamino-3-vinylcephalosporanic acid derivatives and processes for the preparation thereof. Fujisawa Pharmaceutical, Oblon Fisher Spivak McClelland & Maier, October 11, 1983: US04409214 (31 worldwide citation)

This invention relates to novel 7-acylamino-3-vinyl-cephalosporanic acid derivatives and pharmaceutically acceptable salts thereof, of high antimicrobial activity.


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Teraji Tsutomu, Sakane Kazuo, Goto Jiro: New cephem compounds, processes for their preparation, pharmaceutical compositions containing them and their starting compounds.. Fujisawa Pharmaceutical Co, October 13, 1982: EP0062321-A2 (31 worldwide citation)

Cephem compounds of the formula wherein R is amino or a protected amino group; R is lower aliphatic hydrocarbon group which may be substituted with suitable substituent(s), or cyclo (lower)alkenyl; and a group of the formula: is a heterocyclic cation group containing more than one nitrogen atom whic ...


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Shiokawa Youichi, Akahane Atsushi, Katayama Hirohito, Mitsunaga Takafumi: Use of adenosine antagonists in the prevention and treatment of pancreatitis and ulcer.. Fujisawa Pharmaceutical Co, August 5, 1992: EP0497258-A2 (31 worldwide citation)

A pharmaceutical composition for the prevention and/or the treatment of pancreatitis and/or ulcer which comprises, as an active ingredient, an adenosine antagonist or a pharmaceutically acceptable salt thereof in admixture with a pharmaceutically acceptable carrier or excipient.