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Seizo Sunago, Osamu Aoki: Transfusion device. Fujisawa Pharmaceutical, Oblon Spivak McClelland Maier & Neustadt, May 3, 1994: US05308347 (66 worldwide citation)

A transfusion device comprising a flexible vessel containing a solvent fluid, a drug container containing a drug, and a communicating portion for communicating the vessel and the container with each other, the commuicating portion comprising first and second passages adapted to communicate with the ...


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Hemmi Keiji, Neya Masahiro, Fukami Naoki, Hashimoto Masashi, Tanaka Hirokazu, Kayakiri Natsuko: Peptides having endothelin antagonist activity, a process for preparation thereof and pharmaceutical compositions comprising the same.. Fujisawa Pharmaceutical Co, November 21, 1991: EP0457195-A2 (66 worldwide citation)

The present invention relates to peptide compound and a pharmaceutically acceptable salt thereof which have pharmacological activities such as endothelin antagonistic activity and the like, to processes for its preparation, to a pharmaceutical composition comprising the same, and to a method of usin ...


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Kiyoto Sumio, Nishikawa Motoaki, Iwami Morita, Terano Hiroshi, Kohsaka Masanobu, Imanaka Hiroshi: Biologically active ws 6049 substances, a process for the production thereof and their pharmaceutical compositions.. Fujisawa Pharmaceutical Co, November 30, 1983: EP0095154-A1 (64 worldwide citation)

Biologically active WS 6049 substances obtainable by culturing a strain belonging to the genus Actinomadura in an aqueous nutrient medium under aerobic conditions and recovering WS 6049-A substance and/or WS 6049-B substance. The invention also relates to a process for preparing the new substances a ...


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Matsuo Masaaki, Tsuji Kiyoshi, Ogino Takashi, Konishi Nobukiyo: Pyrazole derivatives with antiinflammatory, analgesic and antithrombolic activity.. Fujisawa Pharmaceutical Co, August 11, 1993: EP0554829-A2 (62 worldwide citation)

A compound of the formula : wherein R is aryl which is substituted with substituent(s) selected from the group consisting of lower alkylthio, cyclo(lower)alkyl, hydroxy, hydroxy(lower)alkyl, cyano, lower alkylenedioxy, acyl, acyloxy, aryloxy and lower alkoxy optionally substituted with acyl or lower ...


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Minoru Nakano, Toshinobu Uemura, Shinichi Morizane, Kiyoshi Okuda, Keiko Nakata: Method of producing a solid dispersion of the sparingly water-soluble drug, nilvadipine. Fujisawa Pharmaceutical, Oblon Spivak McClelland Maier & Neustadt, August 23, 1994: US05340591 (60 worldwide citation)

A solid dispersion and a method of producing a solid dispersion of a sparingly water-soluble drug characterized by mixing the sparingly water-soluble drug and a water-soluble polymer at a temperature where neither the water-soluble drug nor water-soluble polymer is melted.


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Honbo Toshiyasu, Hata Takehisa, Ishino Akihiro, Tsuji Yoshiharu: Hair revitalizing agent.. Fujisawa Pharmaceutical Co, April 24, 1991: EP0423714-A2 (58 worldwide citation)

A hair revitalizing agent including a compound represented by the formula shown below or a pharmaceutically acceptable salt thereof: (wherein R to R, R to R, X, Y, and n are the same as defined in the present specification).


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Setoi Hiroyuki, Ohkawa Takehiko, Zenkoh Tatsuya, Hemmi Keiji, Tanaka Horokazu: Benzamide derivatives and their use as vasopressin antagonists.. Fujisawa Pharmaceutical Co, October 19, 1994: EP0620216-A1 (58 worldwide citation)

A compound of the formula : wherein R is hydrogen or lower alkyl, R is hydrogen, lower alkyl, halo(lower)alkyl, halogen or lower alkoxy, R and R are each hydrogen, lower alkyl or taken together to form oxo, R is hydrogen, halogen, nitro, hydroxy, protected hydroxy, lower alkyl or lower alkoxy option ...


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Masakuni Okuhara, Hirokazu Tanaka, Toshio Goto, Tohru Kino, Hiroshi Hatanaka: Method for immunosuppression. Fujisawa Pharmaceutical Company, Oblon Spivak McClelland Maier & Neustadt, May 29, 1990: US04929611 (58 worldwide citation)

This invention relates to tricyclo compounds useful for treatment and prevention of resistance by transplantation, graft-versus-host diseases by medulla ossium transplantation, autoimmune diseases, infectious diseases, and the like, which can be represented by the following formula: ##STR1## to a pr ...


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Matsuo Masaaki, Hagiwara Daijiro, Manabe Takashi, Nobukiyo Konishi, Shigenaga Shinji, Murano Kenji, Matsuda Hiroshi, Miyake Hiroshi: Piperazine derivatives as tachykinin antagonists.. Fujisawa Pharmaceutical Co, May 31, 1995: EP0655442-A1 (56 worldwide citation)

A compound of the following general formula : wherein X is carbonyl or sulfonyl; Y is bond or lower alkylene; R is halogen, lower alkyl, halo(lower)alkyl, aryloxy, nitro or amino which may have 1 or 2 and same or different substituent(s) selected from lower alkyl, acyl and lower alkanesulfonyl; R is ...