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Shichiri Motoaki, Hattori Kiyoshi, Nishiyama Taichiro, Shingu Yasuhiko, Takagi Kiyotaka, Higuchi Mamoru, Okamoto Norihiko, Okudaira Toshiyuki: Portable artificial pancreas.. Fujisawa Pharmaceutical Co, January 18, 1984: EP0098592-A2 (629 worldwide citation)

A portable artificial pancreas comprising a blood sugar detecting unit including electrode means to be inserted into the living body for measuring the blood sugar of the living body, an injection unit including a container for a blood sugar control agent and a feed pump for the control agent and ada ...


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Yoshio Ueda, Takehisa Hata, Hisami Yamaguchi, Satoshi Ueda, Masateru Kodani: Time-controlled explosion systems and processes for preparing the same. Fujisawa Pharmaceutical, Oblon Spivak McClelland Maier & Neustadt, October 3, 1989: US04871549 (121 worldwide citation)

The invention relates to a Time-Controlled Explosion System in which drug release is caused by explosion of a membrane after a definite time period, said System comprising a preparation in the form of a bead or granule, said preparation comprising a core, a drug, swelling agent and an outer membrane ...


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Keiji Hemmi, Masahiro Neya, Keisuke Imai, Natsuko Kayakiri, Masashi Hashimoto: Renin inhibitor peptide compounds, a process for the preparation thereof and pharmaceutical composition comprising the same. Fujisawa Pharmaceutical Company, Oblon Spivak McClelland Maier & Neustadt, October 16, 1990: US04963530 (109 worldwide citation)

A compound of the formula: ##STR1## wherein R.sup.1 is aryl optionally substituted with a substituent selected from the group consisting of halogen and halo(lower)alkyl; lower alkyl or cyclo(lower)alkyl; and


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Masaaki Matsuo, Kiyoshi Tsuji, Nobukiyo Konishi, Katsuya Nakamura: Pyrazole derivatives, and pharmaceutical composition comprising the same. Fujisawa Pharmaceutical, Oblon Spivak McClelland Maier & Neustadt, July 28, 1992: US05134142 (104 worldwide citation)

The present invention concerns pyrazole derivatives of formula: ##STR1## used for the treatment of inflammation, pain, thrombosis and rheumatism.


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Masakuni Okuhara, Hirokazu Tanaka, Toshio Goto, Tohru Kino, Hiroshi Hatanaka: Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same. Fujisawa Pharmaceutical Company, Oblon Spivak McClelland Maier & Neustadt, January 16, 1990: US04894366 (104 worldwide citation)

This invention relates to tricyclo compounds useful for treatment and prevention of resistance by transplantation, graft-versus-host diseases by medulla ossium transplantation, autoimmune diseases, infectious diseases, and the like, which can be represented by the following formula: ##STR1## to a pr ...


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Takashi Morishita, Takehisa Hata, Mitio Mori, Shohachi Tanoue: Multiple soft capsules and production thereof. Morishita Jintan, Fujisawa Pharmaceutical, Oblon Fisher Spivak McClelland & Maier, September 22, 1987: US04695466 (96 worldwide citation)

The present invention relates to a multiple soft capsule in which a soft capsule is contained in another soft capsule and the production thereof. The multiple soft capsule is useful for various industrial fields such as medicine, foods, table luxuries and the like. Especially, the multiple capsule i ...


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Osamu Aoki, Kiyonori Okada, Seizo Sunago, Hitoshi Futagawa, Kohji Ikeda, Shuji Hasegawa: Fluid container. Fujisawa Pharmaceutical, Nissho Corporation, Oblon Spivak McClelland Maier & Neustadt, June 26, 1990: US04936841 (95 worldwide citation)

Disclosed is a fluid container having a flexible bag containing a diluent and having a closing film at its upper end, a capsule connected to the flexible bag, a drug container held in the capsule and a communicating member for communicating the flexible bag with the drug container. The communicating ...


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Matsuo Masaaki, Hagiwara Daijiro, Miyake Hiroshi: Peptide compounds, process for preparation thereof and pharmaceutical composition comprising the same.. Fujisawa Pharmaceutical Co, October 31, 1990: EP0394989-A2 (93 worldwide citation)

A compound of the formula : wherein R is lower alkyl, aryl, arylamino, pyridyl, pyrrolyl, pyrazolopyridyl, quinolyl, or a group of the formula : wherein the symbol of a line and dotted line is a single bond or a double bond, X is CH or N, and Z is O, S or NH, each of which may have suitable substitu ...


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Matsuo Masaaki, Tsuji Kiyoshi, Konishi Nobukiyo, Nakamura Katsuya: Pyrazole derivatives, processes for preparation thereof and pharmaceutical composition comprising the same.. Fujisawa Pharmaceutical Co, March 27, 1991: EP0418845-A1 (82 worldwide citation)

A compound of the formula : wherein R is aryl which may be substituted with substituent(s) selected from the group consisting of lower alkyl, halogen, lower alkoxy, lower alkylthio, lower alkylsulfinyl, lower alkylsulfonyl, hydroxy, lower alkylsulfonyloxy, nitro, amino, lower alkylamino, acylamino a ...