1
Marc Unger, Ian D Manger, Michael Lucero, Yong Yi, Emily Miyashita Lin, Anja Weinecke, Geoffrey Facer: Microfluidic device and methods of using same. Fluidigm Corporation, Townsend and Townsend and Crew, October 10, 2006: US07118910 (223 worldwide citation)

A variety of elastomeric-based microfluidic devices and methods for using and manufacturing such devices are provided. Certain of the devices have arrays of reaction sites to facilitate high throughput analyses. Some devices also include reaction sites located at the end of blind channels at which r ...


2
Marc A Unger, Hou Pu Chou, Ian D Manger, Dave Fernandes, Yong Yi: Microfluidic devices for introducing and dispensing fluids from microfluidic systems. Fluidigm Corporation, Townsend and Townsend Crew, October 4, 2005: US06951632 (143 worldwide citation)

The present invention provides microfluidic devices, systems and methods for using the same, which facilitate the introduction of fluid to and from a microfluidic channel located within the microfluidic devices.


3
Marc Unger, Jiang Huang, Emerson Quan: Microfluidic devices and methods of using same. Fluidigm Corporation, Townsend and Townsend and Crew, January 13, 2009: US07476363 (142 worldwide citation)

An M×N matrix microfluidic device for performing a matrix of reactions, the device having a plurality of reaction cells in communication with one of either a sample inlet or a reagent inlet through a via formed within an elastomeric block of the device. Methods provided include a method for forming ...


4
Hany Ramez Nassef, Geoffrey Facer, Joseph W Barco: Crystal growth devices and systems, and methods for using same. Fluidigm Corporation, Townsend and Townsend and Crew, October 9, 2007: US07279146 (140 worldwide citation)

High throughput screening of crystallization of a target material is accomplished by simultaneously introducing a solution of the target material into a plurality of chambers of a microfabricated fluidic device. The microfabricated fluidic device is then manipulated to vary the solution condition in ...


5
Gregory Harris, James Montgomery, Michael Lee, Gajus Worthington: Object oriented microfluidic design method and system. Fluidigm Corporation, Townsend and Townsend and Crew, April 26, 2005: US06885982 (134 worldwide citation)

The present invention provides for the design of a microfluidic system, including a microfluidic chip or circuit, using an object oriented microfluidic computer aided design system. In an embodiment of the present invention, in a computer system having a computer memory and an object-oriented enviro ...


6
Hou Pu Chou, Antoine Daridon, Kevin Farrell, Brian Fowler, Yish Hann Liau, Ian D Manger, Hany Ramez Nassef, William Throndset: Microfluidic particle-analysis systems. Fluidigm Corporation, Townsend and Townsend and Crew, December 25, 2007: US07312085 (130 worldwide citation)

The invention provides systems, including apparatus, methods, and kits, for the microfluidic manipulation and/or detection of particles, such as cells and/or beads. The invention provides systems, including apparatus, methods, and kits, for the microfluidic manipulation and/or analysis of particles, ...


7
Heid Christian A, Daridon Antoine: Analysis using microfluidic partitioning devices. Fluidigm Corporation, Heid Christian A, Daridon Antoine, APPLE Randolph T, April 19, 2007: WO/2007/044091 (119 worldwide citation)

The invention relates to methods, reagents and devices for detection and characterization of nucleic acids, cells, and other biological samples. Assay method are provided in which a sample is partitioned into sub-samples, and analysis of the contents of the sub-samples carried out. The invention als ...


8
Jiang Huang, Hou Pu Chou, Marc A Unger: Microfluidic chromatography. Fluidigm Corporation, Townsend and Townsend and Crew, June 22, 2004: US06752922 (114 worldwide citation)

The present invention is directed to a microfluidic chromatography apparatus comprising a microfabricated fluid delivery system and a chromatography column which is in fluid communication with the fluid delivery system, and a method for producing and using the same. Preferably, the chromatography co ...


9
Michael Lee, Gajus Worthington, Gregory Harris, James Montgomery: Microfluidic design automation method and system. Fluidigm Corporation, Townsend and Townsend and Crew, April 28, 2009: US07526741 (107 worldwide citation)

The present invention generally relates to microfluidics and more particularly to the design of customized microfluidic systems using a microfluidic computer aided design system. In one embodiment of the present invention a microfluidic circuit design method is provided. The method includes developi ...


10
Michael Lee, Gajus Worthington, Gregory Harris, James Montgomery: Microfluidic design automation method and system. Fluidigm Corporation, Gregory Lynn Heinkel, Townsend and Townsend and Crew, December 7, 2004: US06829753 (106 worldwide citation)

The present invention generally relates to microfluidics and more particularly to the design of customized microfluidic systems using a microfluidic computer aided design system. In one embodiment of the present invention a microfluidic circuit design method is provided. The method includes developi ...