1
Francesco Della Valle, Gabriella Calderini, Alessandro Rastrelli, Aurelio Romeo: Biocompatible perforated membranes, processes for their preparation, their use as a support in the in vitro growth of epithelial cells, the artificial skin obtained in this manner, and its use in skin grafts. Fidia S p A, Birch Stewart Kolasch & Birch, July 5, 1994: US05326356 (221 worldwide citation)

It is provided biocompatible membranes constructed of materials of natural, synthetic or semisynthetic origin, and having a thickness of between 10 and 500.mu., characterised by containing an ordered series of holes of a constant size between 10 and 1000.mu., separated from each other by a constant ...


2
Francesco della Valle, Aurelio Romeo: Esters of hyaluronic acid. Fidia S p A, Birch Stewart Kolasch & Birch, July 25, 1989: US04851521 (185 worldwide citation)

The invention concerns the esters of hyaluronic acid in which all or only a portion of the carboxylic groups of the acid are esterfied, and the salts of the partial esters with metals or with pharmacologically acceptable organic bases.


3
Francesco della Valle, Aurelio Romeo: Cross-linked esters of hyaluronic acid. Fidia S p A, Birch Stewart Kolasch & Birch, September 18, 1990: US04957744 (142 worldwide citation)

Cross-linked esters of hyaluronic acid are provided which result from the esterification of polyhydric alcohols with two or more carboxy groups of the hyaluronic acid polysaccharide. These cross-linked esters are useful in the field of biodegradable plastics for sanitary and surgical articles and in ...


4
Della Valle Francesco, Romeo Aurelio, Lorenzi Silvana: Hyaluronic acid fractions having pharmaceutical activity, methods for preparation thereof, and pharmaceutical compositions containing the same.. Fidia, April 24, 1985: EP0138572-A2 (127 worldwide citation)

Two pharmaceutically useful fractions of hyaluronic acid are obtained comprising a first fraction with a molecular weight between 50,000 and 100,000 which is useful for wound healing, and a second fraction having a molecular weight between 500,000 and 730,000 which is useful for intraocular and intr ...


5
Della Valle Francesco Dr, Romeo Aurelio Prof: Crosslinked carboxy polysaccharides.. Fidia, November 15, 1989: EP0341745-A1 (121 worldwide citation)

Inter and/or intramolecular cross-linked esters of acid polysaccharides are disclosed in which a part or all of the carboxy groups are esterified with hydroxyl groups of the same molecule and/or of different molecules of the acid polysaccharide. These inner cross-linked esters of polysaccharide acid ...


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Francesco della Valle, Aurelio Romeo, Silvana Lorenzi: Hyaluronics acid fractions, methods for the preparation thereof, and pharmaceutical compositions containing same. Fidia S p A, Birch Stewart Kolasch & Birch, November 24, 1992: US05166331 (108 worldwide citation)

Two pharmaceutically useful fractions of hyaluronic acid are obtained comprising a first fraction with a molecular weight between 50,000 and 100,000 which is useful for wound healing, and a second fraction having a molecular weight between 500,000 and 730,000 which is useful for intraocular and intr ...


8
Francesco Della Valle, Aurelio Romeo: Crosslinked carboxy polysaccharides. Fidia S p A, Birch Stewart Kolasch & Birch, October 14, 1997: US05676964 (93 worldwide citation)

Inter and/or intramolecular cross-linked esters of acid polysaccharides are disclosed in which a part or all of the carboxy groups are esterified with hydroxyl groups of the same molecule and/or of different molecules of the acid polysaccharide. These inner cross-linked esters of polysaccharide acid ...


9
Della Valle Francesco, Romeo Aurelio, Lorenzi Silvana: New medicaments for topical use.. Fidia, October 15, 1986: EP0197718-A2 (93 worldwide citation)

Pharmaceutical preparations for non-topical administration containing a pharmacologically active substance together with hyaluronic acid or a molecular weight fraction thereof. The hyaluronic acid may be in the form of the free acid or may be a salt with an alkali or alkaline earth metal, magnesium, ...


10
Francesco della Valle, Aurelio Romeo: Polysaccharide esters and their salts. Fidia S p A, Birch Stewart Kolasch & Birch, October 23, 1990: US04965353 (91 worldwide citation)

The invention concerns the esters of hyaluronic acid in which all or only a portion of the carboxylic groups of the acid are esterified, and the salts of the partial esters with metals or with pharmacologically acceptable organic bases.