1

2
Bousamra Steven, Chittajallu Siva, Galley Paul, Thukral Ajay, Wagner Robin, Weinert Stefan: A system and method providing for user intervention in a diabetes control arrangement. Roche Diagnostics, Fhoffmann La Roche, KÜNG Peter, December 14, 2006: WO/2006/131288 (61 worldwide citation)

A system providing for user intervention in a medical control arrangement may comprise a first user intervention mechanism responsive to user selection thereof to produce a first user intervention signal, a second user intervention mechanism responsive to user selection thereof to produce a second u ...


3
Endl Josef, Eugui Elsie, Fuentes Maria, Graus Yvo, Labrijn Aran, Lanzendoerfer Martin, Parren Paul, Rebers Frank, Schumacher Ralf, Seeber Stefan, Van de, Winkel Jan, Van, Vugt Martine: Anti-ox40l antibodies. Fhoffmann La Roche, Endl Josef, Eugui Elsie, Fuentes Maria, Graus Yvo, Labrijn Aran, Lanzendoerfer Martin, Parren Paul, Rebers Frank, Schumacher Ralf, Seeber Stefan, Van de, Winkel Jan, Van, Vugt Martine, SCHREINER Siegfried, March 23, 2006: WO/2006/029879 (42 worldwide citation)

This invention relates to anti-OX40L antibodies and, in particular, to anti-OX40L antibodies and variants thereof that contain a Fc part derived from human origin and do not bind complement factor C1q. These antibodies have new and inventive properties causing a benefit for a patient suffering from ...


4
Boehringer Markus, Kuhn Bernd, Luebbers Thomas, Mattei Patrizio, Narquizian Robert, Wessel Hans Peter: Hexahydropyridoisoqinolines as dpp-iv inhibitors. Fhoffmann La Roche, Boehringer Markus, Kuhn Bernd, Luebbers Thomas, Mattei Patrizio, Narquizian Robert, Wessel Hans Peter, sWASCHBUESCH Klaus, January 6, 2005: WO/2005/000846 (40 worldwide citation)

The present invention relates to compounds of formula (I) wherein R1 is as defined in the description and claims, and pharmaceutically acceptable salts thereof. The compounds are useful for the treatment and/or prophylaxis of diseases which are associated with DPP-IV, such as diabetes, particularly ...


5
Jolidon Synese, Narquizian Robert, Norcross Roger David, Pinard Emmanuel: Heterocyclic substituted phenyl methanones as inhibitors of the glycine transporter 1. Fhoffmann La Roche, Jolidon Synese, Narquizian Robert, Norcross Roger David, Pinard Emmanuel, POPPE Regina, August 10, 2006: WO/2006/082001 (34 worldwide citation)

The present invention relates to compounds of general formula (I) wherein (i) is an aromatic or partially aromatic bicyclic amine, which may contain one or two additional N-atoms, selected from the group consisting of (a), (b), (c), (d), (e), (f), (g), (h) and to pharmaceutically acceptable acid add ...


6
Fotouhi Nader, Haley Gregory Jay, Simonsen Klaus B, Vu Binh Thanh, Webber Stephen Evan: Novel cis-imidazolines. Fhoffmann La Roche, Fotouhi Nader, Haley Gregory Jay, Simonsen Klaus B, Vu Binh Thanh, Webber Stephen Evan, KLEIN Thomas, November 24, 2005: WO/2005/110996 (32 worldwide citation)

Formula (I) and the pharmaceutically acceptable salts and esters thereof, wherein X1, X2, X3,Y1, Y2 and R are described herein inhibit the interaction of MDM2 protein with a p53-like peptide and hence have anti proiferative activity.


7
Arora Nidhi, Billedeau Roland J, Dewdney Nolan James, Gabriel Tobias, Goldstein David Michael, Mccaleb Kristen Lynn, Soth Michael, Trejo Martin Teresa Alejandra: Heteroaryl-fused pyrazolo derivatives. Fhoffmann La Roche, Arora Nidhi, Billedeau Roland J, Dewdney Nolan James, Gabriel Tobias, Goldstein David Michael, Mccaleb Kristen Lynn, Soth Michael, Trejo Martin Teresa Alejandra, HEIROTH Ulrike, September 15, 2005: WO/2005/085248 (31 worldwide citation)

Compounds of formula (I): where A, B, X, Y, Z, k, R1, R2 and R3 are those defined herein, and compositions comprising the same. The present invention also provides methods for preparing compounds of formula (I) and using the same in treating p38 mediated disorders in a patient.


8
Roe Steven N, Raney Charles C, List Hans: Lancets for bodily fluid sampling supplied on a tape. Roche Diagnostics, Fhoffmann La Roche, Roe Steven N, Raney Charles C, List Hans, BRADSHAW John M, November 17, 2005: WO/2005/107596 (30 worldwide citation)

A supply of lancets (28) for a multi-use lancing device are carried by a tape (22) and sequentially brought from a storage position to an activating position by advancing the tape around a bend (39). The lancets are non-circular in cross-section along their longitudinal lengths, and in their activat ...


9
Ceccarelli Simona Maria, Pinard Emmanuel, Stalder Henri: Triaza-spiropiperidine derivatives for use as glyt-1 inhibitors in the treatment of neurological and neuropsychiatric disorders. Fhoffmann La Roche, Ceccarelli Simona Maria, Pinard Emmanuel, Stalder Henri, POPPE Regina, May 6, 2005: WO/2005/040166 (30 worldwide citation)

The invention relates to compounds of the general formula (I), wherein A-A is -CH2-CH2-, -CH2-CH2-CH2-, -CH2-0- or -0-CH2-; x is hydrogen or hydroxy; R1 is aryl or heteroaryl, unsubstituted or substituted by one or more substituents, selected from the group consisting of lower alkyl, lower alkoxy, h ...


10
Burke David W, Marquant Michael: Test strip with slot vent opening. Roche Diagnostics, Fhoffmann La Roche, Burke David W, Marquant Michael, sBARTOL Michael C, December 29, 2004: WO/2004/113901 (30 worldwide citation)

The test strip (10) includes a base substrate (12), a spacing layer (14) and a covering layer (16) comprising body cover (18) and chamber cover (20). The spacing layer (14) includes a void portion (22) to provide a sample-receiving chamber (24) extending between the base substrate (12) and the cover ...