1
James E Woiszwillo, Larry R Brown, Terrence L Scott, Jie Di, Judith Sudhalter, Charles D Blizzard: Macromolecular microparticles and methods of production and use. Epic Therapeutics, Jones & Askew, July 18, 2000: US06090925 (165 worldwide citation)

Microparticles formed by mixing a macromolecule with a polymer at a pH near the isoelectric point of the macromolecule and incubating the mixture in the presence of an energy source for a predetermined length of time. The microparticles are composed of homogeneously distributed, intertwined macromol ...


2
James E Woiszwillo, Larry R Brown, Terrence L Scott, Jie Di, Judith Sudhalter, Charles D Blizzard, Frank J Riske: Macromolecular microparticles and methods of production and use. Epic Therapeutics, Jones & Askew, November 9, 1999: US05981719 (145 worldwide citation)

Microparticles formed by mixing a macromolecule with a polymer at a pH near the isoelectric point of the macromolecule and incubating the mixture in the presence of an energy source for a predetermined length of time. The microparticles are composed of homogeneously distributed, intertwined macromol ...


3
James E Woiszwillo, Larry R Brown, Terrence L Scott, Jie Di, Judith Sudhalter, Charles D Blizzard, Frank J Riske: Macromolecular microparticles and methods of production and use. Epic Therapeutics, Wolf Greenfield & Sacks P C, July 31, 2001: US06268053 (114 worldwide citation)

Methods relating to the field of biochemistry and more specifically relating to microparticles for use in diagnostics, therapeutics, and research are provided.


4
Terrence L Scott, Larry R Brown, Frank J Riske, Charles D Blizzard, Julia Rashba Step: Sustained release microspheres. Epic Therapeutics, Wolf Greenfield & Sacks P C, October 1, 2002: US06458387 (90 worldwide citation)

Methods for forming sustained release microspheres and the products produced thereby are provided. The microspheres have a smooth surface that includes a plurality of channel openings that are less than 1000 angstroms in diameter.


5
Scott Terence L, Brown Larry R, Riske Frank J, Blizzard Charles D, Rashba Step Julia: Sustained release microspheres. Epic Therapeutics, December 20, 2000: EP1060741-A1 (46 worldwide citation)

Methods for forming sustained release microspheres and the products produced thereby are provided. The microspheres have a smooth surface that includes a plurality of channel openings that are less than 1000 angstroms in diameter.


6
James E Woiszwillo, Larry R Brown, Terrence L Scott, Jie Di, Judith Sudhalter, Charles D Blizzard: Macromolecular microparticles and methods of production and use. Epic Therapeutics, Jones Askew, December 15, 1998: US05849884 (7 worldwide citation)

Microparticles formed by mixing a macromolecule with a polymer at a pH near the isoelectric point of the macromolecule and incubating the mixture in the presence of an energy source for a predetermined length of time. The microparticles are composed of homogeneously distributed, intertwined macromol ...


7
Scott Terrence L, Brown Larry R, Riske Frank J, Blizzard Charles D, Rashba Step Julia: Sustained release microspheres. Epic Therapeutics, July 24, 2002: EP1223917-A1 (1 worldwide citation)

Methods for forming sustained release micropheres and the products produced thereby are provided. The microspheres have a smooth surface that includes a plurality of channel openings that are less than 1000 angstroms in diameter.


8
Brown Larry R: Production of microspheres. Epic Therapeutics, August 20, 2003: EP1335661-A2

Protein microspheres are produced by contacting an aqueous solution of a macromolecule and a polymer with a surface at a high surface area to volume ratio, and heating the solution. The microspheres are useful for preparing pharmaceuticals of defined dimensions which can be delivered to a patient by ...


9
Riske Frank J, Rothstein Fred, Woiszwillo James E: Viral inactivation of biological fluids with biomolecule activity retention. Epic Therapeutics, sGATES Edward R, March 12, 1998: WO/1998/009660

The invention involves methods for inactivating virus in biological fluid preparations such as IgG and products produced thereby. The method involves maintaining the biological fluid preparations such as IgG at an elevated pH for sufficient period of time and under conditions whereby the preparation ...


10
Brown Larry R: Production of microspheres. Epic Therapeutics, Brown Larry R, PLUMER Elizabeth R, June 6, 2002: WO/2002/043580

Protein microspheres are produced by contacting an aqueous solution of a macromolecule and a polymer with a surface at a high surface area to volume ratio, and heating the solution. The microspheres are useful for preparing pharmaceuticals of defined dimensions which can be delivered to a patient by ...