1
James Say, Michael F Tomasco, Adam Heller, Yoram Gal, Behrad Aria, Ephraim Heller, Phillip John Plante, Mark S Vreeke: Electrochemical analyte. E Heller & Company, Merchant & Gould P C, October 17, 2000: US06134461 (1139 worldwide citation)

An electrochemical analyte sensor formed using conductive traces on a substrate can be used for determining and/or monitoring a level of analyte in in vitro or in vivo analyte-containing fluids. For example, an implantable sensor may be used for the continuous or automatic monitoring of a level of a ...


2
Adam Heller, Benjamin J Feldman, James Say, Mark S Vreeke: Small volume in vitro analyte sensor. E Heller & Company, Merchant & Gould P C, November 7, 2000: US06143164 (1003 worldwide citation)

A sensor designed to determine the amount and concentration of analyte in a sample having a volume of less than about 1 .mu.L. The sensor has a working electrode coated with a non-leachable redox mediator. The redox mediator acts as an electron transfer agent between the analyte and the electrode. I ...


3
Adam Heller, Michael V Pishko: Subcutaneous glucose electrode. E Heller & Company, Merchant & Gould P C, October 12, 1999: US05965380 (958 worldwide citation)

A small diameter flexible electrode designed for subcutaneous in vivo amperometric monitoring of glucose is described. The electrode is designed to allow "one-point" in vivo calibration, i.e., to have zero output current at zero glucose concentration, even in the presence of other electroreactive sp ...


4
Adam Heller, Michael V Pishko: Subcutaneous glucose electrode. E Heller & Company, Merchant & Gould P C, December 19, 2000: US06162611 (951 worldwide citation)

A small diameter flexible electrode designed for subcutaneous in vivo amperometric monitoring of glucose is described. The electrode is designed to allow "one-point" in vivo calibration, i.e., to have zero output current at zero glucose concentration, even in the presence of other electroreactive sp ...


5
Adam Heller, Michael V Pishko: Electrochemical analyte measurement system. E Heller & Company, Merchant & Gould P C, September 19, 2000: US06121009 (950 worldwide citation)

A small diameter flexible electrode designed for subcutaneous in vivo amperometric monitoring of glucose is described. The electrode is designed to allow "one-point" in vivo calibration, i.e., to have zero output current at zero glucose concentration, even in the presence of other electroreactive sp ...


6
Adam Heller, Ruben Maidan: Interferant eliminating biosensor. E Heller & Company, Pravel Hewitt Kimball & Krieger, October 18, 1994: US05356786 (908 worldwide citation)

Interferant eliminating analyte sensors and sensing process prevent erroneous assays. Glucose electrodes were coated with an oxidizing enzyme (peroxidase) which allows hydrogen peroxide to selectively oxidize ascorbate, urate, bilirubin, and acetaminophenol in the presence of glucose. Hydrogen perox ...


7
Adam Heller, Michael V Pishko: Electrochemical analyte measurement system. E Heller & Company, Merchant & Gould P C, July 4, 2000: US06083710 (890 worldwide citation)

A small diameter flexible electrode designed for subcutaneous in vivo amperometric monitoring of glucose is described. The electrode is designed to allow "one-point" in vivo calibration, i.e., to have zero output current at zero glucose concentration, even in the presence of other electroreactive sp ...


8
Adam Heller, Michael V Pishko: Subcutaneous glucose electrode. E Heller & Company, Merchant & Gould P C, September 4, 2001: US06284478 (843 worldwide citation)

A small diameter flexible electrode designed for subcutaneous in vivo amperometric monitoring of glucose is described. The electrode is designed to allow “one-point” in vivo calibration, i.e., to have zero output current at zero glucose concentration, even in the presence of other electroreactive sp ...


9
Adam Heller, Ruben Maidan: Interferant eliminating biosensors. E Heller & Company, Pravel Hewitt Kimball & Krieger, November 16, 1993: US05262305 (792 worldwide citation)

A biosensor including an interferant-eliminating catalyst and method for analyzing an analyte in a biological sample is disclosed.


10
Brian A Gregg, Adam Heller: Electrode and method for the detection of hydrogen peroxide. E Heller & Company, Pravel Hewitt Kimball & Krieger, June 14, 1994: US05320725 (723 worldwide citation)

An amperometric biosensor and method for the detection of hydrogen peroxide, NADH, or NADPH with high sensitivity includes an electrode having on its testing surface a three-dimensional redox polymer network in which peroxidase is immobilized.