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Donald Joseph Phillip Pinto, James Russell Pruitt, Joseph Cacciola, John Matthew Fevig, Qi Han, Michael James Orwat, Mimi Lifen Quan, Karen Anita Rossi: Nitrogen containing heteroaromatics as factor Xa inhibitors. DuPont Pharmaceuticals Company, February 1, 2000: US06020357 (135 worldwide citation)

The present application describes nitrogen containing heteroaromatics and derivatives thereof of formula I: ##STR1## or pharmaceutically acceptable salt or prodrug forms thereof, wherein J is N or NH and D may be C(.dbd.NH)NH.sub.2, which are useful as inhibitors of factor Xa.


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Kevin R Oldenburg, Gregory F Hollis, Thomas D Y Chung: Apparatus for holding small volumes of liquids. DuPont Pharmaceuticals Company, Blair Q Ferguson, February 22, 2000: US06027695 (75 worldwide citation)

An apparatus for holding liquid, such as a microtiter plate, in which a plurality of wells are formed. Each of the wells have side walls that intersect in an edge that defines the boundary between adjacent wells. The edge boundary prevents liquid from collecting between the wells, thereby causing al ...


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Robert A Galemmo Jr, Celia Dominguez, John M Fevig, Qi Han, Patrick Y Lam, Donald J P Pinto, James R Pruitt, Mimi L Quan: Inhibitors of factor Xa with a neutral P1 specificity group. DuPont Pharmaceuticals Company, David H Vance, December 7, 1999: US05998424 (75 worldwide citation)

The present application describes inhibitors of factor Xa with a neutral P1 specificity group of formula I: ##STR1## or pharmaceutically acceptable salt forms thereof, wherein R and E may be groups such as methoxy and halo.


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Paul Edward Aldrich, Argyrios Georgios Arvanitis, Robert Scott Cheeseman, Robert John Chorvat, Thomas Eugene Christos, Paul Joseph Gilligan, Dimitri Emil Grigoriadis, Carl Nicholas Hodge, Paul John Krenitsky, Everett Latham Scholfield, Sang William Tam, Zelda Rakowitz Wasserman: 1N-alkyl-n-arylpyrimidinamines and derivatives thereof. DuPont Pharmaceuticals Company, Robert W Black, Kenneth B Rubin, Kalim S Fuzail, January 29, 2002: US06342503 (65 worldwide citation)

The present invention provides novel compounds, compounds and pharmaceutical compositions thereof, and methods of using same in the treatment of affective disorders, anxiety, depression, post-traumatic stress disorders, eating disorders, supranuclear palsy, irritable bowel syndrome, immune suppressi ...


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Paul Edward Aldrich, Argyrios Georgios Arvanitis, Rajagopal Bakthavatchalam, James Peter Beck, Robert Scott Cheeseman, Robert John Chorvat, Paul Joseph Gilligan, Carl Nicholas Hodge, Zelda Rakowitz Wasserman: 1N-alkyl-N-arylpyrimidinamines and derivatives thereof. Dupont Pharmaceuticals Company, Monte R Browder, Kenneth B Rubin, August 22, 2000: US06107301 (58 worldwide citation)

The present invention provides novel compounds, compounds and pharmaceutical compositions thereof, and methods of using same in the treatment of affective disorders, anxiety, depression, post-traumatic stress disorders, eating disorders, supranuclear palsy, irritable bowel syndrome, immune suppressi ...


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David J Damphousse, Mikhail Kagan: Hands-free ultrasound probe holder. DuPont Pharmaceuticals Company, Peter L Dolan, July 17, 2001: US06261231 (44 worldwide citation)

The present invention relates to an apparatus for holding a probe and a method for using the same. The apparatus comprises a body portion having a longitudinal bore and a membrane holder positioned over a first end of the body portion. The membrane holder defines an opening which is covered by a mem ...


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David A Nugiel, David J Carini, Susan V Di Meo, Anup P Vidwans, Eddy W Yue: Acylsemicarbazides and their uses. DuPont Pharmaceuticals Company, Peter L Dolan, September 18, 2001: US06291504 (40 worldwide citation)

The present invention relates to the synthesis of a new lass of indeno[1,2-c]pyrazol-4-ones of formula (I):


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