1
Dey Kaka, Gao Donghong Amy, Goldberg Daniel R, Heim Riether Alexander, Mangette John E, Mugge Ingo Andreas, Snow Roger, Swinamer Alan David, Wu Jiang Ping, Xiong Zhaoming, Yang Yu: Ccr10 antagonists. Boehringer Ingelheim International, Boehringer Ingelheim Pharma & Co Kg, Dey Kaka, Gao Donghong Amy, Goldberg Daniel R, Heim Riether Alexander, Mangette John E, Mugge Ingo Andreas, Snow Roger, Swinamer Alan David, Wu Jiang Ping, Xiong Zhaoming, Yang Yu, MORRIS Michael P, April 23, 2009: WO/2009/052078 (21 worldwide citation)

The invention relates to a compound of formula (I) or a tautomer thereof or a pharmaceutically acceptable salt thereof, wherein R1 to R11, W, X, Y, Z, and n are as defined herein. The invention also relates to methods of using the compounds of formula (I) and compositions thereof to treat various di ...


2
Bell Thomas W, Schols Dominique, Dey Kaka, Vermeire Kurt: Triaza compound immunoregulatory agents. University And Community College System Of, Nevada On Behalf Of, The University Of Nevada Reno, Bell Thomas W, Schols Dominique, Dey Kaka, Vermeire Kurt, SULLIVAN Sally A, October 17, 2002: WO/2002/080856

The invention provides certain macrocyclic triaza compounds which down-regulate CD4 expression for use in the treatment of autoimmune diseases and inflammatory diseases or conditions. In a specific embodiment, the invention provides certain naphthalene substituted triaza macrocycles which exhibit hi ...