1
Paul Meller, Jürgen Gross: Apparatus (cuvette) for taking up and storing liquids and for carrying out optical measurements. Dade Behring Marburg, Finnegan Henderson Farabow Garret and Dunner L, April 10, 2001: US06214626 (124 worldwide citation)

An apparatus which permits simultaneous use as reaction vessel for taking up one or more reaction liquids, for incubating and storing these liquids and for carrying out optical measurements is described. The apparatus performs functions of the reaction vessel and functions of the apparatus for liqui ...


2
John Vorpahl: Method of separation employing magnetic particles and second medium. Dade Behring Marburg, Leland K Jordan, Jerome Rosenstock, Theodore J Leitereg, June 23, 1998: US05770388 (89 worldwide citation)

Methods are disclosed for separating a component of interest from a mixture containing the component of interest and other components. The method comprises contacting a first liquid medium containing the component of interest and other components with a second liquid medium that is of different dens ...


3
Edwin F Ullman, Linda M Western, Samuel J Rose: Detection of nucleic acids by formation of template-dependent product. Dade Behring Marburg, Theodore J Leitereg, March 16, 1999: US05882867 (86 worldwide citation)

A method is disclosed for detecting a target polynucleotide sequence. The method comprises incubating an oligonucleotide with the target polynucleotide sequence and a nucleotide polymerase under isothermal conditions wherein at least one nucleotide is added to the 3'-terminus of the oligonucleotide ...


4
Linda M Western, Samuel J Rose, Edwin F Ullman: Oligonucleotide modification, signal amplification, and nucleic acid detection by target-catalyzed product formation. Dade Behring Marburg, Patrick G Gattari, Theodore J Leitereg, August 29, 2000: US06110677 (63 worldwide citation)

A method is disclosed for modifying an oligonucleotide, which method has application to the detection of a polynucleotide analyte. An oligonucleotide is reversibly hybridized with a polynucleotide, for example, a polynucleotide analyte, in the presence of a 5'-nuclease under isothermal conditions. T ...


5
Edwin F Ullman, Hrair Kirakossian, John S Pease, Yuri Daniloff, Daniel B Wagner: Assay method utilizing induced luminescence. Dade Behring Marburg, Patrick G Gattari, Finnegan Henderson Farabow Garrett & Dunner L, June 26, 2001: US06251581 (60 worldwide citation)

Methods are disclosed for determining an analyte in a medium suspected of containing the analyte. One method comprises treating a medium suspected of containing an analyte under conditions such that the analyte, if present, causes a photosensitizer and a chemiluminescent compound to come into close ...


6
Linda M Western, Samuel J Rose, Edwin F Ullman: Detection of nucleic acids by target-catalyzed product formation. Dade Behring Marburg, Theodore J Leitereg, David M Maiorana, August 11, 1998: US05792614 (56 worldwide citation)

A method is disclosed for modifying an oligonucleotide, which method has application to the detection of a polynucleotide analyte. An oligonucleotide is reversibly hybridized with a polynucleotide, for example, a polynucleotide analyte, in the presence of a 5'-nuclease under isothermal conditions. T ...


7
Karlheinz Enssle, Roland Kurrle, Klaus Dieter Langner, Leander Lauffer, Josef Urban Pauly, Friedrich Robert Seiler: Method for detecting and determining mediators. Dade Behring Marburg, Finnegan Henderson Farabow Garrett and Dunner L, November 5, 2002: US06475717 (49 worldwide citation)

The invention relates to a method for detecting and determining mediators and/or their derivatives in fluids, the mediator being detected directly or indirectly with the aid of a recombinant, soluble receptor for the mediator to be detected.


8
Linda M Western, Samuel J Rose, Edwin F Ullman: Detection of nucleic acids by target-catalyzed product formation. Dade Behring Marburg, Patrick Gattari, September 19, 2000: US06121001 (40 worldwide citation)

A method is disclosed for modifying an oligonucleotide, which method has application to the detection of a polynucleotide analyte. An oligonucleotide is reversibly hybridized with a polynucleotide, for example, a polynucleotide analyte, in the presence of a 5'-nuclease under isothermal conditions. T ...


9
Ralf Otto, Hugo Wilmes, Hans Dieter Sänger: Closure appliance for reagent containers. Dade Behring Marburg, Finnegan Henderson Farabow Garrett and Dunner L, March 15, 2005: US06866820 (36 worldwide citation)

The invention relates to an appliance for opening and closing a reagent-container stopper in a partially or fully automatic analysis apparatus, and to the method, which is applied by means of this appliance, for opening and closing a reagent-container stopper in a partially or fully automatic analys ...


10
Michael Kraus: Method for determining analytes in body fluids and also a new implantable measurement device. Dade Behring Marburg, Finnegan Henderson Farabow Garrett and Dunner L, March 6, 2001: US06198950 (36 worldwide citation)

The present invention relates to an implantable diagnostic apparatus for determining analytes in body fluids, which comprises a plurality of identical and/or different measurement units for determining an analytic parameter, in which a signal is generated which is specifically related to the variabl ...